Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(7R,8R,9R)-2.3-Dimethyl-8-hydroxy-7(2-methoxyethoxy)- 9-phenyl-7.8.9.10-tetrahydro-imidazo-[1.2-h].[1.7].- naphthyridine----[1] 301 💬
24-Methylpyrazole----[1] 301 💬
3[ACU-4429]----[1] 301 💬
4[ARC1905]----[1] 301 💬
5[EU/3/13/1208 orphan]----[1] 301 💬
6AAVB-039----[1] 301 💬
7ACDN-01----[2] 90, 301 💬
8ACU-4429----[1] 301 💬
9ALK-001----[1] 301 💬
10ALK-001 (No generic name)----[1] 301 💬
11ARC1905----[1] 301 💬
12ARC1905 20 MG/ML----[1] 301 💬
13Avacincaptad pegol[1] Avacincaptad pegol[1] Avacincaptad pegol sodium 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 301 💬
14DC6001----[1] 301 💬
15Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)----[2] 90, 301 💬
16Disulfiram[1] Disulfiram[1] Disulfiram 💬 [3] ALDH1B1,
ALDH2,
ALDH3A2 💬 		[13] Alcoholic liver disease, Arginine and proline metabolism, Ascorbate and aldarate metabolism, Fatty acid degradation, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Lysine degradation, Pantothenate and CoA biosynthesis, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[3] 46, 90, 301 💬
17Docosahexaenoic Acid (DHA) Dietary Supplement----[2] 13, 301 💬
18Emixustat[1] Emixustat[1] Emixustat 💬 --[1] 301 💬
19Emixustat hydrochloride[1] Emixustat[1] Emixustat 💬 --[1] 301 💬
20EMIXUSTAT HYDROCHLORIDE (ACU-4429)[1] Emixustat[1] Emixustat 💬 --[1] 301 💬
21Gene Therapy Product-MCO-010----[2] 90, 301 💬
22Gene Therapy-vMCO-010----[1] 301 💬
23Genetic: Blood and/or skin biopsy----[2] 90, 301 💬
24Genetic: HG005----[1] 301 💬
25Genetic: JWK006----[1] 301 💬
26Genetic: OPGx-BEST1----[1] 301 💬
27Genetic: RTx-021----[1] 301 💬
28Genetic: SB-007----[1] 301 💬
29HESC-RPE----[1] 301 💬
30Injection----[2] 6, 301 💬
31Interferon Gamma[1] Interferon Gamma---[9] 18, 65, 85, 96, 107, 228, 299, 301, 326 💬
32INTERFERON GAMMA-1B[2] Interferon Gamma,
Interferon gamma-1b		[1] Interferon gamma-1b 💬 [2] IFNGR1,
IFNGR2 💬 		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
33LBS-008, BPN-14967----[1] 301 💬
34Lentiviral vector containing ABCA4 gene----[1] 301 💬
35Lentiviral vector containing the ABCA4 gene----[1] 301 💬
36Long term follow up in all patients who received SAR422459 in previous study TDU13583[1] SAR422459---[1] 301 💬
37MA09-hRPE----[1] 301 💬
38Madeos----[1] 301 💬
39Mesenchymal Stem Cell-Derived Exosomes[1] Mesenchymal Stem Cell-Derived Exosomes---[2] 127, 301 💬
40Metformin[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
41METFORMIN HYDROCHLORIDE[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[5] 81, 158, 265, 299, 301 💬
42OCU410ST[1] OCU410ST---[1] 301 💬
43OpCT-001----[3] 90, 301, 303 💬
44Oral disulfiram[1] Disulfiram[1] Disulfiram 💬 [3] ALDH1B1,
ALDH2,
ALDH3A2 💬 		[13] Alcoholic liver disease, Arginine and proline metabolism, Ascorbate and aldarate metabolism, Fatty acid degradation, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Lysine degradation, Pantothenate and CoA biosynthesis, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[2] 90, 301 💬
45Other: Saline----[8] 2, 6, 46, 97, 98, 256, 274, 301 💬
46Other: Standard of Care Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 90, 301 💬
47Other: Visual Acuity (VA)----[2] 90, 301 💬
48Over the counter DHA/EPA dietary supplementation----[1] 301 💬
49Ranibizumab[1] Ranibizumab[1] Ranibizumab 💬 [1] VEGFA 💬 [24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[4] 34, 166, 227, 301 💬
50Ranibizumab injection (0.5 mg)[1] Ranibizumab[1] Ranibizumab 💬 [1] VEGFA 💬 [24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[2] 166, 301 💬
51Saffron supplementation----[1] 301 💬
52SAR422459[1] SAR422459---[1] 301 💬
53Sham----[4] 90, 211, 301, 303 💬
54Sildenafil[1] Sildenafil[2] Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
55SORAPRAZAN[1] Soraprazan---[1] 301 💬
56SPVN06----[2] 90, 301 💬
57StarGen----[1] 301 💬
58Stem/progenitor cells transplantation----[2] 90, 301 💬
59STG-001[1] STG-001---[1] 301 💬
60Tinlarebant[1] Tinlarebant[1] Tinlarebant 💬 --[1] 301 💬
61TinlarebantProduct Code: LBS-008, BPN-14967Pharmaceutical Form: TabletINN or Proposed INN: TinlarebantCAS Number: NACurrent Sponsor code: LBS-008, BPN-14967Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 5-Pharmaceutical form of the placebo: TabletRoute of administration of the placebo: Oral use----[1] 301 💬
62TOBRAMYCIN[1] Tobramycin[2] Tobramycin ,
Tobramycin sulfate 💬 		--[2] 299, 301 💬
63Vett Lentiviral con gene ABCA4----[1] 301 💬
64VG801----[1] 301 💬
65Zimura----[1] 301 💬