Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1* D.3.6.2.1 - valore : Every 4 weeks dosing of 200 mg----[1] 41 💬
2* D.3.6.2.1 - valore :Every 4 weeks dosing of 400 mg----[1] 41 💬
317,21-Dihydroxypregna-1,4-diene-3,11,20-trione----[1] 41 💬
418FDG PET scan----[1] 41 💬
5[18F]PEG-Folate----[2] 41, 46 💬
6[ABT-494]----[7] 41, 46, 49, 96, 97, 107, 271 💬
7[AIN457]----[2] 41, 107 💬
8[CNTO1959]----[4] 37, 41, 96, 97 💬
9[NA]----[34] 3, 6, 11, 13, 14, 19, 28, 35, 41, 46, 49, 50, 53, 57, 62, 63, 65, 75, 79, 85, 90, 96, 97, 98, 113, 127, 162, 195, 223, 229, 251, 294, 299, 302 💬
10Abatacept[1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
11ABT-494----[7] 41, 46, 49, 96, 97, 107, 271 💬
12Adalimumab[1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[22] 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
13Additional blood samples----[1] 41 💬
14AIN457----[9] 13, 37, 41, 46, 56, 96, 97, 107, 271 💬
15Alendronate versus alfacalcidol (1-alpha OH vitamin D)[2] Alfacalcidol,
Vitamin D		[1] Alfacalcidol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[3] 41, 46, 50 💬
16Alfacalcidol[1] Alfacalcidol[1] Alfacalcidol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[10] 41, 46, 49, 50, 96, 107, 222, 223, 235, 238 💬
17Anakinra[1] Anakinra[1] Anakinra 💬 [2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[22] 2, 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 57, 84, 86, 97, 106, 107, 149, 153, 266, 299 💬
18Anti-Thymocyte Globulin----[19] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 63, 65, 164, 283, 284, 285 💬
19Autologous peripheral blood stem cell transplantation----[9] 28, 40, 41, 42, 45, 46, 49, 63, 283 💬
20AzaFol----[1] 41 💬
21Baricitinib[1] Baricitinib[1] Baricitinib 💬 [2] JAK1,
JAK2 💬 		[37] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[24] 2, 13, 40, 41, 46, 49, 50, 51, 53, 54, 56, 63, 65, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
22Blood samples----[14] 13, 41, 46, 49, 51, 61, 63, 96, 97, 160, 167, 227, 240, 271 💬
23Bosentan[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
24Bosentan and dapagliflozin[2] Bosentan,
Dapagliflozin		[3] Bosentan ,
Bosentan ,
Dapagliflozin 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 40, 41 💬
25BOSENTAN MYLAN[1] Bosentan[2] Bosentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 41 💬
26Capsule di prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
27CNTO 136----[2] 41, 46 💬
28CNTO1959----[4] 37, 41, 96, 97 💬
29Combination Product: mavrilimumab[1] Mavrilimumab[1] Mavrilimumab 💬 [1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[1] 41 💬
30CORTANCYL----[1] 41 💬
31Cortancyl ® 1 mg----[1] 41 💬
32Cortancyl ® 20 mg----[1] 41 💬
33Cortancyl ® 5 mg----[1] 41 💬
34Corticoids+ tocilizumab 8mg/Kg/4 weeks[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
35Corticosteroid (CS)----[1] 41 💬
36Corticosteroids----[13] 41, 46, 49, 63, 64, 97, 107, 113, 164, 222, 223, 296, 300 💬
37Corticosteroids for Systemic Use----[1] 41 💬
38Cosentyx----[4] 41, 107, 269, 271 💬
39Cosentyx 300 mg solution for injection in pre-filled syringe----[1] 41 💬
40Cosentyx 300mg solution for injection in pre-filled syringe----[1] 41 💬
41Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
42Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
43Dapagliflozin[1] Dapagliflozin[1] Dapagliflozin 💬 --[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
44Diagnostic Test: 3'mRNA sequencing----[1] 41 💬
45Diagnostic Test: 3D T1 MRI sequences injected with fat saturation and black blood----[1] 41 💬
46Diagnostic Test: 68-Ga HA-DOTATATE PET/CT[1] Dotatate---[1] 41 💬
47Diagnostic Test: Analysis of blood and microbiome samples (stool, oral lavage)----[1] 41 💬
48Diagnostic Test: Angio-Optical Coherence Tomography----[1] 41 💬
49Diagnostic Test: Aortic/ cardiac magnetic resonance imaging----[1] 41 💬
50Diagnostic Test: Cell-based ex-vivo assay with high-content analysis----[1] 41 💬
51Diagnostic Test: Color Fundus Photography----[1] 41 💬
52Diagnostic Test: Contrast-Enhanced Ultrasound----[1] 41 💬
53Diagnostic Test: Enzyme-linked immunosorbent assay----[1] 41 💬
54Diagnostic Test: Flow cytometry----[1] 41 💬
55Diagnostic Test: Fluorescein and Indocyanine green Angiography[3] Fluorescein,
Indocyanine green,
Indocyanine green acid form		[3] Fluorescein ,
Indocyanine green ,
Fluorescein sodium 💬 		--[1] 41 💬
56Diagnostic Test: Fluorescein angiography[1] Fluorescein[2] Fluorescein ,
Fluorescein sodium 💬 		--[1] 41 💬
57Diagnostic Test: Functional assessment questionnaires----[1] 41 💬
58Diagnostic Test: Fundus autofluorescence----[1] 41 💬
59Diagnostic Test: High-resolution Optical Coherence Tomography----[1] 41 💬
60Diagnostic Test: Immunohistochemistry of Temporal Artery Biopsies----[1] 41 💬
61Diagnostic Test: Laboratory assessment:----[1] 41 💬
62Diagnostic Test: Optical coherence tomography angiography----[1] 41 💬
63Diagnostic Test: Transorbital Ultrasound----[1] 41 💬
64Diagnostic Test: Vascular ultrasound----[1] 41 💬
65Diagnostic Test: Zirconium Zr 89 labelled rituximab[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[1] 41 💬
66Discontinue Tocilizumab[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
67Dotatate[1] Dotatate---[5] 19, 41, 75, 84, 238 💬
68Encorton----[1] 41 💬
69FDG----[2] 41, 84 💬
70Filgrastim[1] Filgrastim[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[30] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
71Fluorescein[1] Fluorescein[2] Fluorescein ,
Fluorescein sodium 💬 		--[4] 19, 22, 41, 97 💬
72FLUORINE-18----[1] 41 💬
73Gevokizumab[1] Gevokizumab[1] Gevokizumab 💬 [1] IL1B 💬 [43] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[4] 41, 50, 56, 269 💬
74Glucocorticoid Treatment----[1] 41 💬
75Glucocorticoids----[13] 35, 40, 41, 43, 44, 49, 60, 61, 62, 75, 96, 221, 300 💬
76GSK2973327----[1] 41 💬
77GUSELKUMAB[1] Guselkumab[1] Guselkumab 💬 [1] IL23A 💬 [9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[7] 37, 41, 51, 96, 97, 161, 269 💬
78H02AB09----[1] 41 💬
79Hydrocortisone[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
80Hydrokortison----[1] 41 💬
81Hydrokortison orion----[1] 41 💬
82Hydroxychloroquine[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
83Indocyanine green[2] Indocyanine green,
Indocyanine green acid form		[1] Indocyanine green 💬 --[9] 22, 41, 46, 51, 96, 235, 278, 291, 296 💬
84Infliximab[1] Infliximab[1] Infliximab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
85Kevzara ®----[1] 41 💬
86KINERET----[8] 41, 49, 54, 57, 65, 106, 266, 299 💬
87KPL-301----[1] 41 💬
88L04AC07----[2] 41, 46 💬
89Lodotra----[1] 41 💬
90Lodotra (delayed release prednisolone)[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
91MAVRILIMUMAB[1] Mavrilimumab[1] Mavrilimumab 💬 [1] CSF2RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[2] 41, 46 💬
92Methotrexate[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
93Methotrexate treatment[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[2] 41, 46 💬
94Methylprednisolone[1] Methylprednisolone[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
95METOJECT----[6] 41, 46, 96, 97, 107, 271 💬
96Naltrexone[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
97NALTREXONE HYDROCHLORIDE[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[9] 10, 40, 41, 42, 43, 44, 45, 96, 97 💬
98Nivolumab[1] Nivolumab[1] Nivolumab 💬 [1] PDCD1 💬 [3] Cell adhesion molecule (CAM) interaction, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
99Other: 18F-FDG PET/CT----[1] 41 💬
100Other: Blood sample----[37] 2, 11, 13, 34, 35, 41, 44, 46, 48, 49, 50, 51, 53, 58, 61, 63, 65, 84, 86, 96, 97, 113, 160, 162, 177, 222, 223, 227, 234, 238, 240, 256, 279, 299, 335, 340, 348 💬
101Other: Data collection for cellular analyses (Immune subset composition, GCR expression, in vitro steroid responsiveness)----[1] 41 💬
102Other: Data collection for correlation between clinical defined and lab defined GC responsivness----[1] 41 💬
103Other: Data collection for exploratory analyses of endogenous steroid hormones----[1] 41 💬
104Other: Data collection for Prednisone metabolism[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
105Other: IV steroids combination alone----[1] 41 💬
106Other: Questionnaires----[8] 3, 6, 13, 41, 46, 77, 96, 226 💬
107Other: Usual medical management of patients, additional blood and stool samples for biobanking----[6] 40, 41, 46, 48, 53, 56 💬
108Over encapsulated prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
109PET10----[1] 41 💬
110PET3----[1] 41 💬
111Pr----[1] 41 💬
112Prednisolon 1 mg JENAPHARM----[1] 41 💬
113Prednisolon 10 mg JENAPHARM----[1] 41 💬
114Prednisolon 20 mg JENAPHARM----[1] 41 💬
115Prednisolon 5 mg JENAPHARM----[1] 41 💬
116PREDNISOLONE[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
117Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
118Prednisone and ustekinumab treatment[2] Prednisone,
Ustekinumab		[2] Prednisone ,
Ustekinumab 💬 		[4] IL12A,
IL12B,
IL23A,
NR3C1 💬 		[29] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Neuroactive ligand-receptor interaction, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 41 💬
119Prednisone Capsule[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
120Prednisone Capsules[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
121PredniSONE Tablets USP, 1 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 41, 46 💬
122PredniSONE Tablets USP, 10 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
123PredniSONE Tablets USP, 1mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
124PredniSONE Tablets USP, 2.5 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
125PredniSONE Tablets USP, 2.5mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
126PredniSONE Tablets USP, 20mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
127PredniSONE Tablets USP, 5 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[2] 41, 46 💬
128PredniSONE Tablets USP, 5mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
129PredniSONE Tablets, USP[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 41, 43, 44 💬
130PredniSONE Tablets, USP 10 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
131PredniSONE Tablets, USP 2.5 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
132PredniSONE Tablets, USP 5 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
133PredniSONE Tablets, USP, 1 mg[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
134Prednisone therapy and pharmacokinetic[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
135Prednisone treatment[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 41 💬
136RITUXIMAB[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
137Ro 001-9265----[1] 41 💬
138Ro 001-9265/F02----[1] 41 💬
139Ro 001-9265/F03----[1] 41 💬
140Ro 001-9265/F04----[1] 41 💬
141Ro 487-7533/F10-04----[4] 41, 46, 51, 107 💬
142RoActemra----[7] 41, 44, 46, 51, 86, 107, 271 💬
143RoActemra 162 mg solution for injection in pre-filled syringe----[1] 41 💬
144RoActemre----[1] 41 💬
145S78989----[3] 41, 50, 56 💬
146SARILUMAB[1] Sarilumab[1] Sarilumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[5] 41, 46, 84, 107, 271 💬
147Sarilumab SAR153191[1] Sarilumab[1] Sarilumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
148SECUKINUMAB[1] Secukinumab[1] Secukinumab 💬 [1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[9] 13, 37, 40, 41, 46, 107, 160, 269, 271 💬
149Secukinumab 150 mg[1] Secukinumab[1] Secukinumab 💬 [1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 41 💬
150Secukinumab 300 mg[1] Secukinumab[1] Secukinumab 💬 [1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 41 💬
151Secukinumab 300 mg, s.c.[1] Secukinumab[1] Secukinumab 💬 [1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 41 💬
152Shingrix----[6] 41, 46, 49, 51, 96, 97 💬
153Sirukumab[1] Sirukumab[1] Sirukumab 💬 [1] IL6 💬 [49] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 41, 46 💬
154Sodium chloride[1] Sodium chloride[1] Sodium chloride 💬 --[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
155Tocilizumab[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
156Tocilizumab + Glucocorticoids (GCs)[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
157Tocilizumab 162Mg/0.9Ml Autoinjector[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
158Tocilizumab and IV steroids combination[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
159Tocilizumab Prefilled Syringe[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 41, 46 💬
160TOCILIZUMAB SC[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[3] 41, 46, 107 💬
161Tocilizumab treatment[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41 💬
162Treatment----[2] 41, 299 💬
163Upadacitinib[1] Upadacitinib[3] Upadacitinib ,
Upadacitinib tartrate ,
Upadacitinib hydrate 💬 		[1] JAK1 💬 [27] Coronavirus disease, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[12] 40, 41, 46, 49, 53, 55, 63, 96, 97, 98, 107, 271 💬
164Ustekinumab[1] Ustekinumab[1] Ustekinumab 💬 [3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[17] 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
165Vaccination with 2 doses of Shingrix vaccine----[2] 41, 51 💬
166Vitamin D[1] Vitamin D---[26] 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬
167XOMA 052----[5] 41, 46, 50, 56, 106 💬