1 | Active comparator | - | - | - | - | [5] 6 6, 43, 44, 46, 96 💬
|
2 | Alemtuzumab | [1] Alemtuzumab Alemtuzumab | [1] Alemtuzumab
Alemtuzumab
💬
| - | - | [18] 13 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
|
3 | Avacopan | [1] Avacopan Avacopan | [1] Avacopan
Avacopan
💬
| [1] C5AR1 C5AR1 💬
| [6] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬 | [4] 43 43, 44, 66, 222 💬
|
4 | Azathioprine | [1] Azathioprine Azathioprine | [2] Azathioprine
Azathioprine
,
Azathioprine sodium
💬
| - | - | [22] 6 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
|
5 | Belimumab | [1] Belimumab Belimumab | [1] Belimumab
Belimumab
💬
| [1] TNFSF13B TNFSF13B 💬
| [4] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | [13] 11 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 95, 222, 296 💬
|
6 | Belimumab 10 MG/KG | [1] Belimumab Belimumab | [1] Belimumab
Belimumab
💬
| [1] TNFSF13B TNFSF13B 💬
| [4] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | [3] 43 43, 46, 49 💬
|
7 | Benlysta 400 MG powder FOR concentrate FOR solution FOR infusion | [1] Belimumab Belimumab | [1] Belimumab
Belimumab
💬
| [1] TNFSF13B TNFSF13B 💬
| [4] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | [2] 43 43, 49 💬
|
8 | Benlysta 400MG polvere PER concentrato PER soluzione PER infusione | [1] Belimumab Belimumab | [1] Belimumab
Belimumab
💬
| [1] TNFSF13B TNFSF13B 💬
| [4] Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬 | [1] 43 43 💬
|
9 | Blisibimod | [1] Blisibimod Blisibimod | [1] Blisibimod
Blisibimod
💬
| - | - | [5] 43 43, 44, 49, 63, 66 💬
|
10 | CCX168 | - | - | - | - | [6] 43 43, 44, 49, 66, 109, 222 💬
|
11 | CD19- bcma CAR-T cells | - | - | - | - | [4] 43 43, 49, 51, 53 💬
|
12 | Cellcept | [1] Mycophenolate mofetil Mycophenolate mofetil | [2] Mycophenolate mofetil
Mycophenolate mofetil
,
Mycophenolate mofetil hydrochloride
💬
| [2] IMPDH IMPDH, IMPDH 💬
| [2] Drug metabolism - other enzymes Drug metabolism - other enzymes, Purine metabolism 💬 | [5] 11 11, 13, 42, 43, 49 💬
|
13 | Chimeric monoclonal antibody, IGG4 subtype | - | - | - | - | [2] 43 43, 44 💬
|
14 | Corticosteroid and azathioprine | - | - | - | - | [4] 42 42, 43, 44, 45 💬
|
15 | Cyclophosphamide | [1] Cyclophosphamide Cyclophosphamide | [2] Cyclophosphamide
Cyclophosphamide
,
Cyclophosphamide
💬
| - | - | [44] 11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 224, 265, 274, 283, 284, 285, 288, 326, 331 💬
|
16 | Cyclophosphamide, azathioprine,prednisone,methylprednisolone | [2] Cyclophosphamide Cyclophosphamide, Prednisone | [3] Cyclophosphamide
Cyclophosphamide
,
Prednisone
,
Cyclophosphamide
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [3] 42 42, 43, 45 💬
|
17 | Deltacortene | - | - | - | - | [2] 43 43, 97 💬
|
18 | Endoxan baxter | - | - | - | - | [3] 13 13, 43, 96 💬
|
19 | Galen® tablet | - | - | - | - | [2] 43 43, 44 💬
|
20 | Glucocorticoids | - | - | - | - | [10] 35 35, 40, 41, 43, 44, 75, 96, 221, 222, 300 💬
|
21 | Glucocorticoids - reduced dose | - | - | - | - | [2] 43 43, 44 💬
|
22 | Glucocorticoids - standard dose | - | - | - | - | [2] 43 43, 44 💬
|
23 | Human normal immunoglobulin | [1] Human immunoglobulin G Human immunoglobulin G | [1] Globulin, immune
Globulin, immune
💬
| - | - | [8] 11 11, 13, 14, 43, 45, 50, 63, 65 💬
|
24 | Hydroxychloroquine | [1] Hydroxychloroquine Hydroxychloroquine | [2] Hydroxychloroquine sulfate
Hydroxychloroquine sulfate
,
Hydroxychloroquine
💬
| - | - | [26] 6 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
|
25 | Idefirix | [1] Imlifidase Imlifidase | [1] Imlifidase
Imlifidase
💬
| - | - | [3] 43 43, 44, 113 💬
|
26 | IFX-1 | [1] Vilobelimab Vilobelimab | [1] Vilobelimab
Vilobelimab
💬
| [1] C5 C5 💬
| [11] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | [3] 43 43, 44, 269 💬
|
27 | Imlifidase | [1] Imlifidase Imlifidase | [1] Imlifidase
Imlifidase
💬
| - | - | [4] 43 43, 44, 113, 221 💬
|
28 | Immunoglobulin G cleaving cystein protease derived from E. coli | - | - | - | - | [2] 43 43, 44 💬
|
29 | Infliximab | [1] Infliximab Infliximab | [1] Infliximab
Infliximab
💬
| [1] TNF TNF 💬
| [66] AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [24] 35 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 164, 269, 270, 271 💬
|
30 | Intravenous methyl prednisolone | [1] Prednisolone Prednisolone | [1] Prednisolone
Prednisolone
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [1] 43 43 💬
|
31 | Mabthera | [1] Rituximab Rituximab | [1] Rituximab
Rituximab
💬
| [1] MS4A1 MS4A1 💬
| [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [17] 11 11, 13, 35, 43, 44, 45, 46, 50, 51, 52, 61, 63, 64, 65, 83, 162, 222 💬
|
32 | Mabthera® 100MG | [1] Rituximab Rituximab | [1] Rituximab
Rituximab
💬
| [1] MS4A1 MS4A1 💬
| [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [1] 43 43 💬
|
33 | Mabthera® 500MG | [1] Rituximab Rituximab | [1] Rituximab
Rituximab
💬
| [1] MS4A1 MS4A1 💬
| [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [1] 43 43 💬
|
34 | Methotrexate | [1] Methotrexate Methotrexate | [2] Methotrexate
Methotrexate
,
Methotrexate sodium
💬
| [2] DHFR DHFR, DHFR 💬
| [3] Folate biosynthesis Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬 | [37] 11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
|
35 | Methylprednisolone | [1] Methylprednisolone Methylprednisolone | [2] Methylprednisolone
Methylprednisolone
,
Methylprednisolone acetate
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [45] 2 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
|
36 | Mycophenolate | [1] Mycophenolic acid Mycophenolic acid | [2] Mycophenolate sodium
Mycophenolate sodium
,
Mycophenolic acid
💬
| [2] IMPDH IMPDH, IMPDH 💬
| [2] Drug metabolism - other enzymes Drug metabolism - other enzymes, Purine metabolism 💬 | [4] 43 43, 84, 162, 228 💬
|
37 | Mycophenolate mofetil | [2] Mycophenolate mofetil Mycophenolate mofetil, Mycophenolic acid | [4] Mycophenolate mofetil
Mycophenolate mofetil
,
Mycophenolate mofetil hydrochloride
,
Mycophenolate sodium
,
Mycophenolic acid
💬
| [2] IMPDH IMPDH, IMPDH 💬
| [2] Drug metabolism - other enzymes Drug metabolism - other enzymes, Purine metabolism 💬 | [32] 2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
|
38 | Mycophenolate mofetil,methotrexate | [2] Mycophenolate mofetil Mycophenolate mofetil, Mycophenolic acid | [4] Mycophenolate mofetil
Mycophenolate mofetil
,
Mycophenolate mofetil hydrochloride
,
Mycophenolate sodium
,
Mycophenolic acid
💬
| [2] IMPDH IMPDH, IMPDH 💬
| [2] Drug metabolism - other enzymes Drug metabolism - other enzymes, Purine metabolism 💬 | [3] 42 42, 43, 45 💬
|
39 | Mycophenolic acid | [1] Mycophenolic acid Mycophenolic acid | [2] Mycophenolate sodium
Mycophenolate sodium
,
Mycophenolic acid
💬
| [2] IMPDH IMPDH, IMPDH 💬
| [2] Drug metabolism - other enzymes Drug metabolism - other enzymes, Purine metabolism 💬 | [8] 11 11, 43, 49, 51, 60, 66, 96, 222 💬
|
40 | Naltrexone hydrochloride | [1] Naltrexone Naltrexone | [2] Naltrexone hydrochloride
Naltrexone hydrochloride
,
Naltrexone
💬
| [3] OPRD1 OPRD1, OPRK1, OPRM1 💬
| [7] Estrogen signaling pathway Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬 | [9] 10 10, 40, 41, 42, 43, 44, 45, 96, 97 💬
|
41 | NO plasma exchange | - | - | - | - | [2] 43 43, 44 💬
|
42 | Obinutuzumab | [1] Obinutuzumab Obinutuzumab | [1] Obinutuzumab
Obinutuzumab
💬
| [1] MS4A1 MS4A1 💬
| [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [5] 43 43, 44, 49, 63, 222 💬
|
43 | Pednisone | - | - | - | - | [2] 43 43, 44 💬
|
44 | Plaquenil - hydroxychloroquine 200MG film coated tablets | [1] Hydroxychloroquine Hydroxychloroquine | [2] Hydroxychloroquine sulfate
Hydroxychloroquine sulfate
,
Hydroxychloroquine
💬
| - | - | [3] 43 43, 44, 45 💬
|
45 | Plasma exchange | - | - | - | - | [7] 13 13, 43, 44, 64, 95, 171, 222 💬
|
46 | Prednisolone | [1] Prednisolone Prednisolone | [1] Prednisolone
Prednisolone
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [38] 3 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
|
47 | Prednison acis® 20 MG | - | - | - | - | [2] 43 43, 44 💬
|
48 | Prednison acis® 5 MG | - | - | - | - | [2] 43 43, 44 💬
|
49 | Prednison acis¿ 20 MG | - | - | - | - | [2] 43 43, 44 💬
|
50 | Prednison acis¿ 5 MG | - | - | - | - | [2] 43 43, 44 💬
|
51 | Prednisone | [1] Prednisone Prednisone | [1] Prednisone
Prednisone
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [54] 2 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
|
52 | Prednisone tablets, USP | [1] Prednisone Prednisone | [1] Prednisone
Prednisone
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [3] 41 41, 43, 44 💬
|
53 | Prednisone, methylprednisolone,cyclophosphamides | [1] Prednisone Prednisone | [1] Prednisone
Prednisone
💬
| [1] NR3C1 NR3C1 💬
| [1] Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [3] 42 42, 43, 45 💬
|
54 | Procalcitonin-variants elisa-assay | [1] Procalcitonin Procalcitonin | - | - | - | [2] 43 43, 44 💬
|
55 | Rapcabtagene autoleucel | - | - | - | - | [3] 43 43, 44, 51 💬
|
56 | Rituximab | [1] Rituximab Rituximab | [1] Rituximab
Rituximab
💬
| [1] MS4A1 MS4A1 💬
| [1] Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [52] 11 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
|
57 | Rixathon 500MG | - | - | - | - | [1] 43 43 💬
|
58 | RO0452294/V01 | - | - | - | - | [2] 43 43, 44 💬
|
59 | RO0452294/V02 | - | - | - | - | [3] 35 35, 43, 44 💬
|
60 | RO106-1443 | - | - | - | - | [1] 43 43 💬
|
61 | SC291 | - | - | - | - | [2] 43 43, 49 💬
|
62 | Sendoxan | - | - | - | - | [2] 13 13, 43 💬
|
63 | Tocilizumab | [1] Tocilizumab Tocilizumab | [1] Tocilizumab
Tocilizumab
💬
| [1] IL6R IL6R 💬
| [11] Coronavirus disease - COVID-19 Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬 | [24] 2 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
|
64 | Vilobelimab | [1] Vilobelimab Vilobelimab | [1] Vilobelimab
Vilobelimab
💬
| [1] C5 C5 💬
| [11] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | [3] 43 43, 44, 269 💬
|
65 | Vitamin D | [1] Vitamin D Vitamin D | - | - | - | [20] 6 6, 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 299 💬
|