Drug Description in Trials / DrugBank / KEGG DRUG


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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
15009111000001105----[1] 43 💬
2[Glucocorticoids (GC)]----[2] 43, 44 💬
3[IFX-1]----[2] 43, 44 💬
4ALEMTUZUMAB[1] Alemtuzumab[1] Alemtuzumab 💬 --[21] 13, 14, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 107, 164, 283, 284, 285, 326 💬
5Avacopan[1] Avacopan[1] Avacopan 💬 [1] C5AR1 💬 [6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬[4] 43, 44, 66, 223 💬
6Azathioprine[1] Azathioprine[2] Azathioprine ,
Azathioprine sodium 💬
--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
7BELIMUMAB[1] Belimumab[1] Belimumab 💬 [1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[17] 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
8Belimumab 10 mg/kg[1] Belimumab[1] Belimumab 💬 [1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 43, 46, 49 💬
9Benlysta----[7] 43, 48, 49, 53, 63, 66, 222 💬
10Benlysta 400 mg powder for concentrate for solution for infusion----[2] 43, 49 💬
11Benlysta 400mg polvere per concentrato per soluzione per infusione----[1] 43 💬
12Blisibimod[1] Blisibimod[1] Blisibimod 💬 --[5] 43, 44, 49, 63, 66 💬
13CCX168----[6] 43, 44, 49, 66, 109, 223 💬
14CD19- BCMA CAR-T cells----[4] 43, 49, 51, 53 💬
15CELLCEPT----[7] 11, 13, 42, 43, 49, 222, 223 💬
16CellCept (Mycophenolate Mofetil)[1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬
[2] IMPDH1,
IMPDH2 💬
[2] Drug metabolism - other enzymes, Purine metabolism 💬[2] 42, 43 💬
17Chimeric monoclonal antibody, IgG4 subtype----[2] 43, 44 💬
18Corticosteroid----[12] 13, 42, 43, 44, 45, 66, 84, 96, 97, 113, 222, 223 💬
19Corticosteroid and azathioprine[1] Azathioprine[2] Azathioprine ,
Azathioprine sodium 💬
--[4] 42, 43, 44, 45 💬
20Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬
--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
21Cyclophosphamide, Azathioprine,prednisone,methylprednisolone[4] Azathioprine,
Cyclophosphamide,
Methylprednisolone,
Prednisone
[7] Azathioprine ,
Cyclophosphamide ,
Methylprednisolone ,
Prednisone ,
Methylprednisolone acetate ,
Azathioprine sodium ,
Cyclophosphamide 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 42, 43, 45 💬
22DELTACORTENE----[2] 43, 97 💬
23Dengue 1,2,3,4 (attenuated) vaccine----[8] 40, 43, 44, 46, 48, 49, 51, 107 💬
24Diagnostic Test: Procalcitonin-variants ELISA-Assay[1] Procalcitonin---[2] 43, 44 💬
25ENDOXAN BAXTER----[3] 13, 43, 96 💬
26GALEN® tablet----[2] 43, 44 💬
27Glucocorticoid (GC)----[3] 43, 44, 46 💬
28Glucocorticoids----[13] 35, 40, 41, 43, 44, 49, 60, 61, 62, 75, 96, 221, 300 💬
29Glucocorticoids (GC)----[2] 43, 44 💬
30Glucocorticoids - Reduced Dose----[2] 43, 44 💬
31Glucocorticoids - Standard Dose----[2] 43, 44 💬
32Glucocorticoids [Reduced Dose]----[2] 43, 44 💬
33Glucocorticoids [Standard Dose]----[2] 43, 44 💬
34Hydroxychloroquine[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬
--[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬
35Idefirix----[3] 43, 44, 113 💬
36IFX-1[1] Vilobelimab[1] Vilobelimab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 43, 44, 269 💬
37Imlifidase[1] Imlifidase[1] Imlifidase 💬 --[4] 43, 44, 113, 221 💬
38Immunoglobulin G cleaving cystein protease derived from E. coli----[2] 43, 44 💬
39Infliximab[1] Infliximab[1] Infliximab 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
40Intravenous immunoglobulins (human immunoglobulins G)----[1] 43 💬
41Intravenous methyl prednisolone[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 43 💬
42Mabthera----[20] 11, 13, 35, 43, 44, 45, 46, 50, 51, 52, 53, 61, 63, 64, 65, 83, 162, 222, 223, 271 💬
43Mabthera®----[7] 13, 35, 43, 44, 46, 63, 93 💬
44MabThera® 100MG----[1] 43 💬
45MabThera® 500MG----[1] 43 💬
46Methotrexate[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬
[2] DHFR,
DHFR2 💬
[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
47Methyl prednisolone[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 43, 49, 96 💬
48Methylprednisolone[1] Methylprednisolone[2] Methylprednisolone ,
Methylprednisolone acetate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
49Methylprednisolone (or other glucocorticoid)[1] Methylprednisolone[2] Methylprednisolone ,
Methylprednisolone acetate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 43 💬
50Mycophenolate[1] Mycophenolic acid[2] Mycophenolate sodium ,
Mycophenolic acid 💬
[2] IMPDH1,
IMPDH2 💬
[2] Drug metabolism - other enzymes, Purine metabolism 💬[4] 43, 84, 162, 228 💬
51Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid
[4] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride ,
Mycophenolate sodium ,
Mycophenolic acid 💬
[2] IMPDH1,
IMPDH2 💬
[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
52Mycophenolate mofetil,methotrexate[2] Methotrexate,
Mycophenolate mofetil
[4] Methotrexate ,
Mycophenolate mofetil ,
Methotrexate sodium ,
Mycophenolate mofetil hydrochloride 💬
[4] DHFR,
DHFR2,
IMPDH1,
IMPDH2 💬
[5] Drug metabolism - other enzymes, Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate, Purine metabolism 💬[3] 42, 43, 45 💬
53Mycophenolic acid[1] Mycophenolic acid[2] Mycophenolate sodium ,
Mycophenolic acid 💬
[2] IMPDH1,
IMPDH2 💬
[2] Drug metabolism - other enzymes, Purine metabolism 💬[9] 11, 43, 49, 51, 60, 66, 96, 222, 223 💬
54Naltrexone[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬
[3] OPRD1,
OPRK1,
OPRM1 💬
[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
55NALTREXONE HYDROCHLORIDE[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬
[3] OPRD1,
OPRK1,
OPRM1 💬
[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[9] 10, 40, 41, 42, 43, 44, 45, 96, 97 💬
56Obinutuzumab[1] Obinutuzumab[1] Obinutuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[6] 43, 44, 49, 63, 222, 223 💬
57Other: Active Comparator----[2] 43, 44 💬
58Other: blood specimen----[4] 43, 96, 97, 329 💬
59Other: No Plasma Exchange----[2] 43, 44 💬
60Pednisone----[2] 43, 44 💬
61Plaquenil - Hydroxychloroquine 200mg Film coated tablets[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬
--[3] 43, 44, 45 💬
62Plasma exchange----[7] 13, 43, 44, 64, 95, 171, 222 💬
63PREDNISOLONE[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
64Prednison acis® 20 mg----[2] 43, 44 💬
65Prednison acis® 5 mg----[2] 43, 44 💬
66Prednison acis¿ 20 mg----[2] 43, 44 💬
67Prednison acis¿ 5 mg----[2] 43, 44 💬
68Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
69Prednisone (and methylprednisolone)[2] Methylprednisolone,
Prednisone
[3] Methylprednisolone ,
Prednisone ,
Methylprednisolone acetate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 43 💬
70PredniSONE Tablets, USP[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 41, 43, 44 💬
71Prednisone, methylprednisolone,cyclophosphamides[2] Methylprednisolone,
Prednisone
[3] Methylprednisolone ,
Prednisone ,
Methylprednisolone acetate 💬
[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 42, 43, 45 💬
72Procalcitonin[1] Procalcitonin---[3] 43, 44, 299 💬
73Rapcabtagene autoleucel----[5] 43, 44, 46, 49, 51 💬
74RITUXIMAB[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
75Rituximab (Arm A)[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[2] 43, 44 💬
76Rituximab (Arm B)[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 43, 44, 63 💬
77Rituximab (R)[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 13, 43, 44 💬
78RIXATHON 500mg----[1] 43 💬
79RO0452294/V01----[2] 43, 44 💬
80RO0452294/V02----[3] 35, 43, 44 💬
81Ro106-1443----[1] 43 💬
82SC291----[2] 43, 49 💬
83Sendoxan----[2] 13, 43 💬
84Standard of Care (SOC)----[5] 43, 44, 49, 85, 171 💬
85Tocilizumab[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
86Vilobelimab[1] Vilobelimab[1] Vilobelimab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 43, 44, 269 💬
87Vitamin D[1] Vitamin D---[26] 3, 6, 13, 15, 19, 41, 43, 44, 46, 49, 50, 68, 74, 93, 95, 96, 97, 98, 179, 222, 228, 235, 256, 274, 298, 299 💬