Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
10 MG prednisone----[1] 44 💬
25 MG prednisone----[1] 44 💬
3AB-101----[4] 35, 44, 46, 49 💬
4Abatacept[1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
5Active comparator----[5] 6, 43, 44, 46, 96 💬
6Alemtuzumab[1] Alemtuzumab[1] Alemtuzumab 💬 --[18] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
7ANTI-interleukin 5 (IL-5) humanized monoclonal----[2] 44, 45 💬
8Avacopan[1] Avacopan[1] Avacopan 💬 [1] C5AR1 💬 [6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Staphylococcus aureus infection 💬[4] 43, 44, 66, 222 💬
9Azathioprin-ratiopharm® 25 MG filmtabletten----[1] 44 💬
10Azathioprine[1] Azathioprine[2] Azathioprine ,
Azathioprine sodium 💬 		--[22] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 63, 65, 66, 84, 85, 94, 95, 96, 97, 162 💬
11Azathioprine 25 MG[1] Azathioprine[2] Azathioprine ,
Azathioprine sodium 💬 		--[1] 44 💬
12AZD7986----[2] 44, 299 💬
13Belimumab[1] Belimumab[1] Belimumab 💬 [1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 95, 222, 296 💬
14Benralizumab[1] Benralizumab[1] Benralizumab 💬 [1] IL5RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299 💬
15Blisibimod[1] Blisibimod[1] Blisibimod 💬 --[5] 43, 44, 49, 63, 66 💬
16CCX168----[6] 43, 44, 49, 66, 109, 222 💬
17Chimeric monoclonal antibody, IGG4 subtype----[2] 43, 44 💬
18Corticosteroid and azathioprine----[4] 42, 43, 44, 45 💬
19Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 224, 265, 274, 283, 284, 285, 288, 326, 331 💬
20Cyclophosphamide followed BY methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[1] 44 💬
21Cyclophosphamide/azathioprine[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[1] 44 💬
22Cyclophosphamidum 500 MG[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[1] 44 💬
23Depemokimab[1] Depemokimab[1] Depemokimab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 45 💬
24Endoxan® 500 MG----[1] 44 💬
25Fasenra[1] Benralizumab[1] Benralizumab 💬 [1] IL5RA 💬 [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬[5] 44, 45, 98, 162, 299 💬
26Fludarabine[1] Fludarabine[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[23] 11, 13, 19, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 326 💬
27Galen® tablet----[2] 43, 44 💬
28Glucocorticoids----[10] 35, 40, 41, 43, 44, 75, 96, 221, 222, 300 💬
29Glucocorticoids - reduced dose----[2] 43, 44 💬
30Glucocorticoids - standard dose----[2] 43, 44 💬
31GSK3511294----[2] 44, 45 💬
32Gusperimus[1] Gusperimus[2] Gusperimus trihydrochloride ,
Gusperimus 💬 		--[1] 44 💬
33Gusperimus + glucocorticoids[1] Gusperimus[2] Gusperimus trihydrochloride ,
Gusperimus 💬 		--[1] 44 💬
34Hydroxychloroquine[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
35Idefirix[1] Imlifidase[1] Imlifidase 💬 --[3] 43, 44, 113 💬
36IFX-1[1] Vilobelimab[1] Vilobelimab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 43, 44, 269 💬
37Imlifidase[1] Imlifidase[1] Imlifidase 💬 --[4] 43, 44, 113, 221 💬
38Immunoglobulin G cleaving cystein protease derived from E. coli----[2] 43, 44 💬
39Imurel----[7] 13, 44, 45, 46, 54, 96, 97 💬
40Imurel 25 MG----[3] 44, 45, 96 💬
41INS1007----[2] 44, 299 💬
42L04ac06----[2] 44, 45 💬
43Laboratory experiments before and after mepolizumab treatment----[2] 44, 45 💬
44Mabthera[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[17] 11, 13, 35, 43, 44, 45, 46, 50, 51, 52, 61, 63, 64, 65, 83, 162, 222 💬
45MEDI-563----[5] 44, 45, 98, 162, 299 💬
46Meperizumab injection----[1] 44 💬
47Mepolizumab[1] Mepolizumab[1] Mepolizumab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[4] 44, 45, 98, 162 💬
48Mesna----[11] 11, 13, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬
49Metex 2,5 MG tabletten----[1] 44 💬
50Methotrexate[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
51Methotrexate 2.5 MG[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[1] 44 💬
52Methotrexate 25 MG[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[1] 44 💬
53Metoject 10 MG/ML, solution injectable EN seringue PRé-remplie[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[1] 44 💬
54Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride ,
Mycophenolate sodium ,
Mycophenolic acid 💬 		[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
55Mycophénolate MOFéTIL----[1] 44 💬
56Naltrexone hydrochloride[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[9] 10, 40, 41, 42, 43, 44, 45, 96, 97 💬
57NO plasma exchange----[2] 43, 44 💬
58NS-229----[2] 44, 45 💬
59Nucala[1] Mepolizumab[1] Mepolizumab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 45 💬
60Nucala 100 MG powder FOR solution FOR injection[1] Mepolizumab[1] Mepolizumab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 45 💬
61Obinutuzumab[1] Obinutuzumab[1] Obinutuzumab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[5] 43, 44, 49, 63, 222 💬
62Orencia[1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[15] 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 160, 222, 271, 300 💬
63Pednisone----[2] 43, 44 💬
64Plaquenil - hydroxychloroquine 200MG film coated tablets[1] Hydroxychloroquine[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[3] 43, 44, 45 💬
65Plasma exchange----[7] 13, 43, 44, 64, 95, 171, 222 💬
66Prednisolone[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[38] 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
67Prednison acis® 20 MG----[2] 43, 44 💬
68Prednison acis® 5 MG----[2] 43, 44 💬
69Prednison acis¿ 20 MG----[2] 43, 44 💬
70Prednison acis¿ 5 MG----[2] 43, 44 💬
71Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
72Prednisone tablets, USP[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 41, 43, 44 💬
73Procalcitonin-variants elisa-assay[1] Procalcitonin---[2] 43, 44 💬
74Rapcabtagene autoleucel----[3] 43, 44, 51 💬
75Recombinant humanized monoclonal antibody specific FOR human IL-5----[1] 44 💬
76Reslizumab[1] Reslizumab[1] Reslizumab 💬 [1] IL5 💬 [13] Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬[2] 44, 98 💬
77Rituximab[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
78RO0452294/V01----[2] 43, 44 💬
79RO0452294/V02----[3] 35, 43, 44 💬
80Roactemra[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[7] 41, 44, 46, 51, 86, 107, 271 💬
81SB-240563----[3] 44, 45, 98 💬
82SHR-1703----[1] 44 💬
83Tezepelumab[1] Tezepelumab[1] Tezepelumab 💬 [1] TSLP 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[3] 44, 45, 98 💬
84Tocilizumab[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [11] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[24] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
85Tofacitinib[1] Tofacitinib[2] Tofacitinib citrate ,
Tofacitinib 💬 		[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[19] 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 96, 97, 107, 110, 162, 271, 300 💬
86Trimethoprim sulfamethoxazole[1] Trimethoprim[3] Trimethoprim ,
Trimethoprim sulfate ,
Trimethoprim hydrochloride 💬 		--[1] 44 💬
87Vilobelimab[1] Vilobelimab[1] Vilobelimab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 43, 44, 269 💬
88Vitamin D[1] Vitamin D---[20] 6, 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 299 💬
89Yellow fever vaccine[1] Yellow fever vaccine[1] Yellow fever vaccine 💬 --[8] 40, 44, 46, 50, 51, 52, 53, 107 💬