Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
12019171-69-6----[1] 61 💬
2[2019171-69-6]----[1] 61 💬
3[ANX005]----[1] 61 💬
4[atovaquone][1] Atovaquone[1] Atovaquone 💬 --[1] 61 💬
5[INCB050465 1 mg]----[1] 61 💬
6[INCB050465 2.5 mg]----[1] 61 💬
7[INCB050465][1] Parsaclisib[1] Parsaclisib 💬 [1] PIK3CD 💬 [106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phagocytosis, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[1] 61 💬
8[M281]----[3] 11, 53, 61 💬
9[N/A]----[11] 2, 11, 13, 20, 28, 46, 51, 61, 65, 97, 299 💬
10[pentamidine][1] Pentamidine[2] Pentamidine isethionate ,
Pentamidine 💬 		--[1] 61 💬
11[R935788]----[1] 61 💬
12[SAR444671]----[2] 61, 300 💬
13[SAR650984]----[1] 61 💬
14[trimethoprim-sulfamethoxazole][2] Sulfamethoxazole,
Trimethoprim		[4] Trimethoprim ,
Sulfamethoxazole ,
Trimethoprim sulfate ,
Trimethoprim hydrochloride 💬 		--[1] 61 💬
15[VAY736]----[4] 49, 53, 61, 63 💬
16Acalabrutinib[1] Acalabrutinib[2] Acalabrutinib ,
Acalabrutinib maleate hydrate 💬 		[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 46, 61 💬
17ACT-HIB Polvere e solvente per soluzione iniettabile in siringa preriempita 0,5 ml----[4] 61, 62, 63, 223 💬
18ALXN1830----[3] 11, 35, 61 💬
19Anti-CD20 monoclonal antibody and the BTK inhibitor----[2] 61, 63 💬
20Anti-CD38 antibody Injection----[3] 48, 61, 63 💬
21ANX005----[3] 2, 8, 61 💬
22APL-2----[6] 2, 61, 62, 66, 222, 223 💬
23Arnovie101 Infusion Intravenous----[2] 49, 61 💬
24Aspaveli----[4] 2, 61, 62, 223 💬
25ATOVAQUONE[1] Atovaquone[1] Atovaquone 💬 --[1] 61 💬
26Autologous CD19-BCMA Dual-Target CAR T-Cell Therapy----[5] 13, 49, 51, 53, 61 💬
27Bendamustine[1] Bendamustine[3] Bendamustine hydrochloride ,
Bendamustine ,
Bendamustine hydrochloride hydrate 💬 		--[6] 13, 28, 49, 50, 51, 61 💬
28BENDAMUSTINE HYDROCHLORIDE[1] Bendamustine[3] Bendamustine hydrochloride ,
Bendamustine ,
Bendamustine hydrochloride hydrate 💬 		--[1] 61 💬
29Bendamustine, Rituximab[2] Bendamustine,
Rituximab		[4] Rituximab ,
Bendamustine hydrochloride ,
Bendamustine ,
Bendamustine hydrochloride hydrate 💬 		[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[1] 61 💬
30BEXSERO – Sospensione iniettabile – Siringa preriempita----[4] 61, 62, 63, 223 💬
31Biological assessment----[1] 61 💬
32BIV009----[2] 61, 162 💬
33BIVV009----[1] 61 💬
34BIVV020----[3] 14, 61, 63 💬
35Blood sample----[33] 2, 3, 6, 8, 10, 13, 14, 19, 34, 46, 48, 49, 51, 53, 61, 63, 65, 66, 67, 77, 79, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 299 💬
36Blood samples----[14] 13, 41, 46, 49, 51, 61, 63, 96, 97, 160, 167, 227, 240, 271 💬
37BMS-986353----[3] 51, 61, 63 💬
38BORTEZOMIB[1] Bortezomib[1] Bortezomib 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[19] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
39CART Infusion----[2] 61, 63 💬
40CC312----[5] 46, 49, 51, 61, 63 💬
41CD19/BCMA CAR T-cells----[3] 16, 49, 61 💬
42CINRYZE® (C1 esterase inhibitor [human])----[1] 61 💬
43CM336 Injection----[2] 61, 63 💬
44CNCT19 CAR-T cell therapy----[1] 61 💬
45Combination of a single dose anti-CD20 antibody and bortezomib[1] Bortezomib[1] Bortezomib 💬 [1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[1] 61 💬
46COMPLEMENT C1 ESTERASE INHIBITOR----[2] 61, 65 💬
47CTX112----[3] 51, 61, 63 💬
48Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
49Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
50Cytokine essays----[2] 61, 63 💬
51ECULIZUMAB[1] Eculizumab[1] Eculizumab 💬 [1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[8] 11, 13, 14, 61, 62, 109, 221, 223 💬
52EFALIZUMAB[1] Efalizumab[1] Efalizumab 💬 [1] ITGAL 💬 [14] Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, IgSF CAM signaling, Integrin signaling, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬
53Eliquis----[3] 61, 222, 223 💬
54Enatumab----[1] 61 💬
55ERYTHROPOIETIN[1] Erythropoietin[4] Epoetin alfa ,
Epoetin epsilon ,
Epoetin theta ,
Epoetin zeta 💬 		[1] EPOR 💬 [7] Cytokine-cytokine receptor interaction, Efferocytosis, Hematopoietic cell lineage, Hormone signaling, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[11] 2, 6, 13, 18, 22, 47, 61, 63, 70, 95, 96 💬
56FAMOTIDINA----[1] 61 💬
57Fecal microbiome----[2] 61, 63 💬
58Fludarabine[1] Fludarabine[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
59Fludarabine phosphate[1] Fludarabine[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[14] 28, 36, 49, 51, 60, 61, 62, 63, 65, 96, 283, 284, 285, 286 💬
60Fostamatinib[1] Fostamatinib[2] Fostamatinib ,
Fostamatinib disodium 💬 		[1] SYK 💬 [18] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phagocytosis, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[5] 46, 49, 61, 63, 66 💬
61Fostamatinib 150 mg bid[1] Fostamatinib[2] Fostamatinib ,
Fostamatinib disodium 💬 		[1] SYK 💬 [18] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phagocytosis, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[1] 61 💬
62Fostamatinib Disodium[1] Fostamatinib[2] Fostamatinib ,
Fostamatinib disodium 💬 		[1] SYK 💬 [18] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phagocytosis, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[4] 46, 61, 63, 66 💬
63Fostamatinib DisodiumProduct Code: R935788Pharmaceutical Form: Film-coated tabletINN or Proposed INN: FostamatinibCAS Number: 914295-16-2Current Sponsor code: Fostamatinib Disodium R935788Other descriptive name: R788, fostamatinib disodium hexahydrate (in USPI/FPI)Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 100-Product Name: Fostamatinib DisodiumProduct Code: R935788Pharmaceutical Form: Film-coated tabletINN or Proposed INN: FostamatinibCAS Number: 914295-16-2Current Sponsor code: Fostamatinib Disodium R935788Other descriptive name: R788, fostamatinib disodium hexahydrate (in USPI/FPI)Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 150-[1] Fostamatinib[2] Fostamatinib ,
Fostamatinib disodium 💬 		[1] SYK 💬 [18] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phagocytosis, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[1] 61 💬
64G-CSF[1] Filgrastim[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[12] 6, 11, 13, 51, 60, 61, 63, 65, 85, 96, 284, 285 💬
65Genetic: Blood sample----[5] 8, 13, 61, 280, 294 💬
66GL-0719[1] GL-0719---[1] 61 💬
67Glucocorticoids----[13] 35, 40, 41, 43, 44, 49, 60, 61, 62, 75, 96, 221, 300 💬
68GT801 Injection----[1] 61 💬
69HAEMOPHILUS INFLUENZAE----[5] 61, 62, 63, 66, 223 💬
70HIBERIX - POLVERE E SOLVENTE PER SOLUZIONE INIETTABILE PER USO INTRAMUSCOLARE 1 FLACONCINO DI POLVERE + 1 SIRINGA PRERIEMPITA DI SOLVENTE DA 0.5 ML----[5] 61, 62, 63, 66, 223 💬
71HMPL-523(300mg PO QD)----[1] 61 💬
72Ianalumab[1] Ianalumab[1] Ianalumab 💬 [1] TNFRSF13C 💬 [5] Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬[8] 35, 46, 49, 51, 53, 61, 63, 95 💬
73IanalumabProduct Code: VAY736Pharmaceutical Form: Concentrate for solution for infusionINN or Proposed INN: IanalumabCurrent Sponsor code: VAY736Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 150-Pharmaceutical form of the placebo: Concentrate for solution for infusionRoute of administration of the placebo: Intravenous use----[2] 61, 63 💬
74IASO-782 injection----[2] 49, 61 💬
75IASO206 injection----[1] 61 💬
76Ibrutinib[1] Ibrutinib[1] Ibrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 28, 60, 61 💬
77Ibrutinib 420 mg[1] Ibrutinib[1] Ibrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 61 💬
78Inaticabtagene Autoleucel[1] Inaticabtagene Autoleucel---[3] 49, 61, 63 💬
79Inaticabtagene autoleucel Injection[1] Inaticabtagene Autoleucel---[3] 49, 61, 63 💬
80INCB050465[1] Parsaclisib[1] Parsaclisib 💬 [1] PIK3CD 💬 [106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phagocytosis, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[2] 35, 61 💬
81INCB050465 1 mg----[1] 61 💬
82INCB050465 2.5 mg----[1] 61 💬
83INCB050465 HYDROCHLORIDE[1] Parsaclisib[1] Parsaclisib 💬 [1] PIK3CD 💬 [106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phagocytosis, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[2] 35, 61 💬
84Interleukine-2----[1] 61 💬
85Iptacopan[1] Iptacopan[2] Iptacopan ,
Iptacopan hydrochloride 💬 		[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[8] 11, 61, 62, 63, 66, 109, 222, 223 💬
86Iptacopan hydrochloride[1] Iptacopan[2] Iptacopan ,
Iptacopan hydrochloride 💬 		[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[5] 61, 63, 66, 109, 223 💬
87Isatuximab[1] Isatuximab[1] Isatuximab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[3] 28, 61, 283 💬
88Isatuximab SAR650984[1] Isatuximab[1] Isatuximab 💬 [1] CD38 💬 [6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[1] 61 💬
89Kappa (light chain)----[1] 61 💬
90KZR-616----[4] 49, 50, 61, 63 💬
91Levact----[1] 61 💬
92Levamisole[1] Levamisole[2] Levamisole hydrochloride ,
Levamisole 💬 		--[4] 60, 61, 62, 222 💬
93LEVOCETIRIZINA DICLORIDRATO----[1] 61 💬
94Levocitirizina----[1] 61 💬
95Linperlisib[1] Linperlisib---[2] 61, 283 💬
96LNP023----[7] 61, 62, 63, 66, 109, 222, 223 💬
97Luspatercept[1] Luspatercept[1] Luspatercept 💬 [1] ACVR2B 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[4] 60, 61, 63, 282 💬
98M281----[5] 11, 46, 49, 53, 61 💬
99M281Product Code: M281Pharmaceutical Form: Solution for injectionINN or Proposed INN: N/ACAS Number: 2211985-36-1Current Sponsor code: M281Other descriptive name: M281Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 30-Pharmaceutical form of the placebo: Solution for injectionRoute of administration of the placebo: Intravenous use----[1] 61 💬
100Mabthera----[20] 11, 13, 35, 43, 44, 45, 46, 50, 51, 52, 53, 61, 63, 64, 65, 83, 162, 222, 223, 271 💬
101Mabthera or biosimilar Rituximab[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[2] 48, 61 💬
102MENVEO – Polvere e soluzione per soluzione iniettabile----[4] 61, 62, 63, 223 💬
103Montelukast[1] Montelukast[2] Montelukast sodium ,
Montelukast 💬 		[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[10] 6, 13, 19, 46, 61, 63, 85, 98, 222, 228 💬
104Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride ,
Mycophenolate sodium ,
Mycophenolic acid 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
105Mycophenolate Mofetil 500mg[1] Mycophenolate mofetil[2] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride 💬 		[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[3] 49, 51, 61 💬
106NGS----[2] 61, 63 💬
107Nimenrix----[4] 50, 61, 63, 223 💬
108Ninlaro----[2] 61, 63 💬
109Nipocalimab[1] Nipocalimab[1] Nipocalimab 💬 --[6] 11, 14, 46, 49, 53, 61 💬
110Obexelimab[1] Obexelimab[1] Obexelimab 💬 [1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[4] 13, 49, 61, 300 💬
111OM336----[2] 61, 63 💬
112Orelabrutinib[1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 13, 49, 53, 61, 63 💬
113Orelabrutinib-100[1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 61 💬
114Orelabrutinib-150[1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 61 💬
115Orelabrutinib-50[1] Orelabrutinib[1] Orelabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 61 💬
116ORILANOLIMAB[1] Orilanolimab[1] Orilanolimab 💬 --[1] 61 💬
117Other: Blood sample----[37] 2, 11, 13, 34, 35, 41, 44, 46, 48, 49, 50, 51, 53, 58, 61, 63, 65, 84, 86, 96, 97, 113, 160, 162, 177, 222, 223, 227, 234, 238, 240, 256, 279, 299, 335, 340, 348 💬
118PARACETAMOLO----[10] 2, 11, 14, 19, 28, 53, 61, 63, 300, 309 💬
119Paraclisib----[1] 61 💬
120Parsaclisib[1] Parsaclisib[1] Parsaclisib 💬 [1] PIK3CD 💬 [106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phagocytosis, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[3] 35, 53, 61 💬
121Parsaclisib (1 mg)[1] Parsaclisib[1] Parsaclisib 💬 [1] PIK3CD 💬 [106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phagocytosis, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[1] 61 💬
122Parsaclisib (2.5 mg)[1] Parsaclisib[1] Parsaclisib 💬 [1] PIK3CD 💬 [106] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Acute myeloid leukemia, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Amoebiasis, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bacterial invasion of epithelial cells, Breast cancer, C-type lectin receptor signaling pathway, Carbohydrate digestion and absorption, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Coronavirus disease, Diabetic cardiomyopathy, Endometrial cancer, Epstein-Barr virus infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, GnRH secretion, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Influenza A, Inositol phosphate metabolism, Insulin resistance, Insulin signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leukocyte transendothelial migration, Lipid and atherosclerosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Measles, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phagocytosis, Phosphatidylinositol signaling system, Phospholipase D signaling pathway, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Small cell lung cancer, Sphingolipid signaling pathway, Spinocerebellar ataxia, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway, mTOR signaling pathway 💬[1] 61 💬
123Parsaclisinib----[1] 61 💬
124PEGCETACOPLAN[1] Pegcetacoplan[1] Pegcetacoplan 💬 [1] C3 💬 [18] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagocytosis, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[4] 2, 61, 62, 223 💬
125Pegcetacoplan (APL-2)[1] Pegcetacoplan[1] Pegcetacoplan 💬 [1] C3 💬 [18] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Integrin signaling, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagocytosis, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 61, 62 💬
126PENTAMIDINA ISETIONATO[1] Pentamidine[2] Pentamidine isethionate ,
Pentamidine 💬 		--[1] 61 💬
127Pentamidine[1] Pentamidine[2] Pentamidine isethionate ,
Pentamidine 💬 		--[1] 61 💬
128Povetacicept[1] Povetacicept[1] Povetacicept 💬 [1] TNFRSF13B 💬 [3] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬[5] 11, 61, 63, 66, 222 💬
129PREDNISOLONE[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
130Prednisolone + mabthera[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 61 💬
131Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
132Prednisone, low dose rituximab[2] Prednisone,
Rituximab		[2] Prednisone ,
Rituximab 💬 		[2] MS4A1,
NR3C1 💬 		[2] Hematopoietic cell lineage, Neuroactive ligand-receptor interaction 💬[1] 61 💬
133PRN1008----[4] 35, 61, 63, 300 💬
134QT-219C Cell Injection----[1] 61 💬
135R788, fostamatinib disodium hexahydrate (in USPI/FPI)[1] Fostamatinib[2] Fostamatinib ,
Fostamatinib disodium 💬 		[1] SYK 💬 [18] B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Coronavirus disease, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagosome formation, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Osteoclast differentiation, PI3K-Akt signaling pathway, Phagocytosis, Phospholipase D signaling pathway, Platelet activation, Tuberculosis, Viral carcinogenesis 💬[1] 61 💬
136R935788----[4] 46, 61, 63, 66 💬
137Raptiva 100 mg/ml powder and solvent for solution for injection----[9] 11, 13, 46, 48, 53, 61, 95, 96, 221 💬
138Recombinant humanized IgG4 monoclonal antibody----[1] 61 💬
139Recombinant humanized monoclonal antibody: IgG4 (heavy chain)----[1] 61 💬
140Rilzabrutinib[1] Rilzabrutinib[1] Rilzabrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[6] 35, 61, 63, 222, 223, 300 💬
141RITUXIMAB[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
142Rituximab (MABTHERA® or RITUXAN®).[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 35, 61, 63 💬
143Rituximab (Mabthera®)[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[1] 61 💬
144RVT-1401----[3] 11, 14, 61 💬
145SAR444671----[3] 61, 63, 300 💬
146SAR445088----[2] 14, 61 💬
147SAR650984----[2] 28, 61 💬
148Sirolimus[1] Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
149Soliris (R)----[1] 61 💬
150Spleen sample----[2] 61, 63 💬
151Sulfamethoxazole[1] Sulfamethoxazole[1] Sulfamethoxazole 💬 --[8] 35, 44, 49, 61, 85, 223, 296, 299 💬
152Sutimlimab[1] Sutimlimab[1] Sutimlimab 💬 [1] C1S 💬 [5] Complement and coagulation cascades, Coronavirus disease, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 61 💬
153Sutimlimab (BIVV009)[1] Sutimlimab[1] Sutimlimab 💬 [1] C1S 💬 [5] Complement and coagulation cascades, Coronavirus disease, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 61 💬
154SYNT001----[1] 61 💬
155Tacrolimus[1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
156ThisCART19A----[1] 61 💬
157Thrombopoietin[1] Thrombopoietin---[4] 47, 60, 61, 63 💬
158Thrombopoietin Receptor Agonist[1] Thrombopoietin---[3] 60, 61, 63 💬
159Thrombopoietin receptor agonist (TPO-RA)[1] Thrombopoietin---[3] 60, 61, 63 💬
160TNT009----[1] 61 💬
161Treatment intervention----[1] 61 💬
162Treatment standard----[1] 61 💬
163Trimethoprim[1] Trimethoprim[3] Trimethoprim ,
Trimethoprim sulfate ,
Trimethoprim hydrochloride 💬 		--[7] 36, 44, 49, 60, 61, 85, 299 💬
164Trimethoprim-Sulfamethoxazole[2] Sulfamethoxazole,
Trimethoprim		[4] Trimethoprim ,
Sulfamethoxazole ,
Trimethoprim sulfate ,
Trimethoprim hydrochloride 💬 		--[3] 49, 61, 299 💬
165TRIMETOPRIM + SULFAMETOSSAZOLO *----[1] 61 💬
166UCAR T-cell group----[3] 11, 49, 61 💬
167Universal allogeneic anti-CD19/BCMA CAR T-cells----[4] 11, 49, 51, 61 💬
168Urine sample----[5] 49, 51, 61, 63, 84 💬
169VACCINO CONTRO IL MEMINGOCOCCO DI GRUPPO B----[5] 61, 62, 63, 66, 223 💬
170VACCINO HAEMOPHILUS INFLUENZAE B CONIUGATO CON TOSSOIDETETANICO----[5] 61, 62, 63, 66, 223 💬
171VACCINO POLISACCARIDICO ANTI-MENINGOCOCCICO (A.C.Y E W-135)----[5] 61, 62, 63, 66, 223 💬
172VAY736----[9] 13, 35, 46, 49, 53, 61, 63, 85, 95 💬
173VELCADE*EV 1FL 3,5MG 1MG/ML----[1] 61 💬
174YTS109----[1] 61 💬
175YTS109 cell----[6] 46, 48, 49, 51, 53, 61 💬
176Zanubrutinib[1] Zanubrutinib[1] Zanubrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[7] 13, 48, 61, 63, 222, 300, 331 💬
177Zanubrutinib Oral Capsule[1] Zanubrutinib[1] Zanubrutinib 💬 [1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 61 💬
178 LNP023 HYDROCHLORIDE SALT----[7] 61, 62, 63, 66, 109, 222, 223 💬