Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1[National Drug Code: 59762-0074]----[1] 81 💬
2[NBI-74788]----[1] 81 💬
3[PREDNISOLONE][1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
4[SPR001]----[1] 81 💬
5AAV BBP-631----[1] 81 💬
6Abiraterone[1] Abiraterone[1] Abiraterone acetate 💬 [1] CYP17A1 💬 [5] Cortisol synthesis and secretion, Cushing syndrome, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[2] 75, 81 💬
7Abiraterone Acetate[2] Abiraterone,
Acetate		[1] Abiraterone acetate 💬 [1] CYP17A1 💬 [5] Cortisol synthesis and secretion, Cushing syndrome, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[2] 75, 81 💬
8Acetate[1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
9ATR-101----[2] 75, 81 💬
10Atumelnant[1] Atumelnant[1] Atumelnant 💬 [1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 75, 81 💬
11Atumelnant (CRN04894)[1] Atumelnant[1] Atumelnant 💬 [1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 81 💬
12Behavioral: quality of life assessment----[1] 81 💬
13Blood drawing----[1] 81 💬
14Bone balance measurements----[1] 81 💬
15Chronocort----[1] 81 💬
16Chronocort 10mg----[1] 81 💬
17Chronocort 5mg----[1] 81 💬
18Chronocort®----[1] 81 💬
19Chronocort® 10 mg----[1] 81 💬
20Chronocort® 20 mg----[1] 81 💬
21Chronocort® 5 mg----[1] 81 💬
22CI-984, 17AA70, PD 132301-2----[1] 81 💬
23Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)[7] Acetate,
Cortisone,
Cortisone acetate,
Dexamethasone,
Hydrocortisone,
Prednisolone,
Prednisone		[8] Hydrocortisone ,
Dexamethasone ,
Prednisolone ,
Prednisone ,
Cortisone acetate ,
Dexamethasone sodium phosphate ,
Cortisone ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
24Cortef----[2] 81, 83 💬
25Cortef 10mg----[1] 81 💬
26Cortef 5mg----[1] 81 💬
27Corticotropin[1] Corticotropin[2] Corticotropin ,
Corticotropin, repository 💬 		[1] MC2R 💬 [6] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[10] 2, 13, 46, 75, 78, 81, 84, 145, 205, 222 💬
28Cortisol[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
29Cortison----[1] 81 💬
30Cortisone[1] Cortisone[1] Cortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
31Cortisone acetate[3] Acetate,
Cortisone,
Cortisone acetate		[2] Cortisone acetate ,
Cortisone 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
32Crinecerfont[1] Crinecerfont[1] Crinecerfont 💬 [1] CRHR1 💬 [5] Cushing syndrome, Hormone signaling, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 81 💬
33Crinecerfont is a novel non-peptide selective corticotropin releasing factor 1 (CRF1 ) receptor antagonist.[2] Corticotropin,
Crinecerfont		[3] Corticotropin ,
Corticotropin, repository ,
Crinecerfont 💬 		[2] CRHR1,
MC2R 💬 		[7] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Hormone signaling, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 81 💬
34CrinecerfontProduct Code: NBI-74788 Pharmaceutical Form: Capsule, hardINN or Proposed INN: CrinecerfontCAS Number: 752253-39-7Current Sponsor code: NBI-74788Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 50-Pharmaceutical form of the placebo: CapsuleRoute of administration of the placebo: Oral use----[1] 81 💬
35Dectancyl----[1] 81 💬
36Dexamethasone[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
37Dexamethasone 0,1 mg Tablets[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
38Dexamethasone 0.5mg Tablet[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
39Dexamethasone 1,5 mg Tablets[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
40Dexamethasone 2mg Tablets[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
41DIURF-006----[1] 81 💬
42Dual release hydrocortisone (plenadren)[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
43Efmody 10 mg modified release hard capsules----[1] 81 💬
44Efmody 5 mg modified release hard capsules----[1] 81 💬
45Fludrocortisone[1] Fludrocortisone[2] Fludrocortisone acetate ,
Fludrocortisone 💬 		[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[3] 6, 17, 81 💬
46Flutamide[1] Flutamide[1] Flutamide 💬 [1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 57, 81 💬
47Hormonal balance measurements----[1] 81 💬
48Hydrocortisone[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
49Hydrocortisone (Solucortef)[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
50HYDROCORTISONE - hydrocortisone tablet[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
51Hydrocortisone 10mg Tablet[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
52Hydrocortisone 10mg Tablets[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
53Hydrocortisone 20mg Tablets[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
54HYDROCORTISONE MICRONIZED[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
55Hydrocortisone Modified Release Capsules[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
56Hydrocortisone sodium acetate[3] Acetate,
Hydrocortisone,
Sodium acetate		[2] Hydrocortisone ,
Sodium acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
57HYDROCORTISONE SODIUM PHOSPHATE[2] Hydrocortisone,
Hydrocortisone phosphate		[2] Hydrocortisone ,
Hydrocortisone sodium phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 53, 81, 83 💬
58HYDROCORTISONE SODIUM SUCCINATE[3] Hydrocortisone,
Hydrocortisone succinate,
Succinic acid		[3] Hydrocortisone ,
Hydrocortisone sodium succinate ,
Hydrocortisone succinate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 81, 83, 97 💬
59Hydrocortisone tablet 2.5 mg[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
60Hydrocortisone withdrawal[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
61HYDROCORTISONE- hydrocortisone tablet[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
62IDROCORTISONE----[1] 81 💬
63Infacort----[1] 81 💬
64Infacort®----[1] 81 💬
65Insulin pump (Medtronic)----[1] 81 💬
66Letrozole[1] Letrozole[1] Letrozole 💬 [1] CYP19A1 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[2] 81, 89 💬
67Lu AG13909----[2] 75, 81 💬
68Metabolic balance measurements----[1] 81 💬
69Metformin[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
70METFORMIN HYDROCHLORIDE[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[5] 81, 158, 265, 299, 301 💬
71Metformine[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 81 💬
72Metformine Sandoz 850 mg filmomhulde tabletten[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 81 💬
73NBI-74788----[1] 81 💬
74NBI-77860----[1] 81 💬
75Nevanimibe[1] Nevanimibe[2] Nevanimibe ,
Nevanimibe hydrochloride 💬 		--[2] 75, 81 💬
76Nevanimibe hydrochloride[1] Nevanimibe[2] Nevanimibe ,
Nevanimibe hydrochloride 💬 		--[2] 75, 81 💬
77Nifedipine[1] Nifedipine[1] Nifedipine 💬 [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 50, 81 💬
78Pioglitazone[1] Pioglitazone[2] Pioglitazone hydrochloride ,
Pioglitazone 💬 		[1] PPARG 💬 [12] AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 223, 229, 265, 298, 299 💬
79PREDNISOLONE[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
80PREDNISOLONE - prednisolone tablet[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
81Prednisolone 1mg Tablets[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
82Prednisolone 2,5 mg Tablets[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
83Prednisolone 5 mg Tablets[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
84Prednisolone 5mg Tablet[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
85Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
86Sodium acetate[2] Acetate,
Sodium acetate		[1] Sodium acetate 💬 --[2] 81, 251 💬
87Sodium succinate[1] Succinic acid---[11] 13, 46, 49, 50, 51, 81, 83, 95, 97, 211, 222 💬
88Solu-Cortef----[3] 6, 81, 83 💬
89SPR001----[1] 81 💬
90Standard Care----[2] 81, 299 💬
91Standard glucocorticoid therapy----[1] 81 💬
92Subcutaneous hydrocortisone[1] Hydrocortisone[1] Hydrocortisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 81 💬
93Testolactone[1] Testolactone[1] Testolactone 💬 [1] CYP19A1 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[1] 81 💬
94TILDACERFONT[1] Tildacerfont[1] Tildacerfont 💬 [1] CRHR1 💬 [5] Cushing syndrome, Hormone signaling, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 81 💬