Drug Description in Trials / DrugBank / KEGG DRUG

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Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[2] Caffeine ,
Caffeine hydrate 💬

[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬

Name	Full Name
ADORA1	adenosine A1 receptor
ADORA2A	adenosine A2a receptor
PDE1B	phosphodiesterase 1B
PDE2A	phosphodiesterase 2A
PDE3A	phosphodiesterase 3A
PDE3B	phosphodiesterase 3B
PDE4A	phosphodiesterase 4A
PDE4B	phosphodiesterase 4B
PDE4C	phosphodiesterase 4C
PDE4D	phosphodiesterase 4D
PDE5A	phosphodiesterase 5A

[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pa ...

[8] 2, 6, 21, 46, 78, 96, 97, 265 💬

2

Caffeine 100-200 mg BID

[2] Caffeine ,
Caffeine hydrate 💬

[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬

Name	Full Name
ADORA1	adenosine A1 receptor
ADORA2A	adenosine A2a receptor
PDE1B	phosphodiesterase 1B
PDE2A	phosphodiesterase 2A
PDE3A	phosphodiesterase 3A
PDE3B	phosphodiesterase 3B
PDE4A	phosphodiesterase 4A
PDE4B	phosphodiesterase 4B
PDE4C	phosphodiesterase 4C
PDE4D	phosphodiesterase 4D
PDE5A	phosphodiesterase 5A

[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pa ...

[1] 6 💬

3

Caffeine alkaloid

[2] Caffeine ,
Caffeine hydrate 💬

[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬

Name	Full Name
ADORA1	adenosine A1 receptor
ADORA2A	adenosine A2a receptor
PDE1B	phosphodiesterase 1B
PDE2A	phosphodiesterase 2A
PDE3A	phosphodiesterase 3A
PDE3B	phosphodiesterase 3B
PDE4A	phosphodiesterase 4A
PDE4B	phosphodiesterase 4B
PDE4C	phosphodiesterase 4C
PDE4D	phosphodiesterase 4D
PDE5A	phosphodiesterase 5A

[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pa ...

[1] 6 💬

4

Dextromethorphan and Caffeine

[2] Caffeine,
Dextromethorphan

[3] Caffeine ,
Caffeine hydrate ,
Dextromethorphan 💬

Name	Other Names
Caffeine	Caffeine (USP) Anhydrous caffeine (JP18) Anhydrous caffeine (TN) Respia (TN)
Caffeine hydrate	Caffeine hydrate (JP18) Caffeine monohydrate Caffeine (TN)
Dextromethorphan	Dextromethorphan (USP)

[17] ADORA1,
ADORA2A,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4 ...

Name	Full Name
ADORA1	adenosine A1 receptor
ADORA2A	adenosine A2a receptor
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D
PDE1B	phosphodiesterase 1B
PDE2A	phosphodiesterase 2A
PDE3A	phosphodiesterase 3A
PDE3B	phosphodiesterase 3B
PDE4A	phosphodiesterase 4A
PDE4B	phosphodiesterase 4B
PDE4C	phosphodiesterase 4C
PDE4D	phosphodiesterase 4D
PDE5A	phosphodiesterase 5A
SIGMAR1	sigma non-opioid intracellular receptor 1

[37] Alcoholism, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyo ...

[1] 78 💬

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