Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
15% lidocaine/5 mg/ml 0.02% estradiol compound cream[2] Estradiol (cis-Estradiol),
Lidocaine		[3] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Lidocaine ,
Lidocaine hydrochloride monohydrate 💬 		[7] ESR1,
ESR2,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[13] Adrenergic signaling in cardiomyocytes, Breast cancer, Chemical carcinogenesis - receptor activation, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Taste transduction, Thyroid hormone signaling pathway 💬[1] 226 💬
2Estradiol[1] Estradiol (cis-Estradiol)[1] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM) 💬 [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299 💬
3Estradiol 2 mg[1] Estradiol (cis-Estradiol)[1] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM) 💬 [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 299 💬
4ESTRADIOL HEMIHYDRATE[1] Estradiol (cis-Estradiol)[1] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM) 💬 [2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 13 💬
5Estradiol valerate[2] Estradiol (cis-Estradiol),
Estradiol valerate (Estradiol Valerate and Estradiol Valerate/Dienogest)		[2] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Estradiol valerate (Estradiol valerate) 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 65 💬
6Estradiolvalerat----[1] 65 💬
7Ethinyl estradiol[2] Estradiol (cis-Estradiol),
Ethinylestradiol (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate)		[2] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Ethinyl estradiol (Ethinyl estradiol) 💬 		[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[3] 46, 49, 299 💬
8ETHINYLESTRADIOL
(Ethinyl estradiol)		[1] Ethinylestradiol (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate)[1] Ethinyl estradiol (Ethinyl estradiol) 💬 [1] ESR1 💬 [9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 13 💬
9Loestrin (norethindrone acetate and ethinyl estradiol)[4] Acetate,
Estradiol (cis-Estradiol),
Ethinylestradiol (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate),
Norethisterone (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate)		[3] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Norethindrone ,
Ethinyl estradiol (Ethinyl estradiol) 💬 		[3] ESR1,
ESR2,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 299 💬
10Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol)[4] Acetate,
Estradiol (cis-Estradiol),
Ethinylestradiol (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate),
Norethisterone (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate)		[3] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Norethindrone ,
Ethinyl estradiol (Ethinyl estradiol) 💬 		[3] ESR1,
ESR2,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 46, 49 💬
11Ortho-cyclen, Ethinyl estradiol/norgestimate, 0.035 mg/0.250 mg[3] Estradiol (cis-Estradiol),
Ethinylestradiol (Norethindrone and Ethinyl Estradiol and Ferrous Fumarate),
Norgestimate (Norgestimate and Ethinyl Estradiol)		[3] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Ethinyl estradiol (Ethinyl estradiol),
Norgestimate 💬 		[3] ESR1,
ESR2,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 299 💬
12Somatropin, Clonidine, L-Arginin-Hydrochloride, Estradiol valerate[5] Arginine,
Clonidine,
Estradiol (cis-Estradiol),
Estradiol valerate (Estradiol Valerate and Estradiol Valerate/Dienogest),
Somatotropin		[4] Estradiol (Estradiol, ESTRADIOL TRANSDERMAL SYSTEM, ESTRADIOL VAGINAL, ESTRADIOL VAGINAL CREAM),
Clonidine ,
Estradiol valerate (Estradiol valerate),
Arginine 💬 		[5] ADRA2A,
ADRA2B,
ADRA2C,
ESR1,
ESR2 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Neuroactive ligand-receptor interaction, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway, cGMP-PKG signaling pathway 💬[1] 65 💬