Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1150-MG ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
2150MG ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
375-MG ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
4CF patients with A G551D mutation and treated with ivacaftor----[1] 299 💬
5Deuterated ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
6Elexacaftor / ivacaftor / tezacaftor[1] Elexacaftor[1] Elexacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
7Elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG, 2 tablets each morning + ivacaftor 150 MG ONE tablet each evening[1] Elexacaftor[1] Elexacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
8Elexacaftor-tezacaftor-ivacaftor exposure[1] Elexacaftor[1] Elexacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
9Elexacaftor-tezacaftor-ivacaftor treatment[1] Elexacaftor[1] Elexacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
10Elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor (Ivacaftor),
Tezacaftor		[3] Ivacaftor (Ivacaftor),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
11Ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[2] 299, 340 💬
12Ivacaftor 125MG tablet[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
13Ivacaftor 150 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
14Ivacaftor 150 MG or 250 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
15Ivacaftor 25 MG/75 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
16Ivacaftor 59,5MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
17Ivacaftor 59.5MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
18Ivacaftor 75 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
19Ivacaftor 75 MG/150 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
20Ivacaftor 75MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
21Ivacaftor and symdeko[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
22Ivacaftor exposed[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
23Ivacaftor or elexacaftor/tezacaftor/ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
24Ivacaftor+lumacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
25Ivacaftor/ataluren[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
26Ivacaftor/kalydeco[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
27Lumacaftor / ivacaftor[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
28Lumacaftor plus ivacaftor[1] Lumacaftor[1] Lumacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
29Lumacaftor plus ivacaftor combination[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
30Lumacaftor, ivacaftor drug combination[1] Lumacaftor[1] Lumacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
31Lumacaftor-ivacaftor[1] Lumacaftor[1] Lumacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
32Lumacaftor-ivacaftor treatment[1] Lumacaftor[1] Lumacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
33Lumacaftor/ivacaftor[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
34Lumacaftor/ivacaftor 100MG/125MG tablets[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
35Lumacaftor/ivacaftor 200MG/125MG[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
36Lumacaftor/ivacaftor 200MG/125MG tablets[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
37Lumacaftor/ivacaftor 200MG/83MG tablet[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
38Orkambi: contains lumacaftor and ivacaftor[2] Ivacaftor (Ivacaftor),
Lumacaftor		[2] Ivacaftor (Ivacaftor),
Lumacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
39Tezacaftor/ivacaftor[2] Ivacaftor (Ivacaftor),
Tezacaftor		[2] Ivacaftor (Ivacaftor),
Tezacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
40Tezacaftor/ivacaftor + ivacaftor[1] Tezacaftor[1] Tezacaftor 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
41Tezacaftor/ivacaftor 100MG/150MG[2] Ivacaftor (Ivacaftor),
Tezacaftor		[2] Ivacaftor (Ivacaftor),
Tezacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
42Tezacaftor/ivacaftor/100MG/150MG[2] Ivacaftor (Ivacaftor),
Tezacaftor		[2] Ivacaftor (Ivacaftor),
Tezacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
43Treatment with cystic fibrosis transmembrane regulator (cftr) modualtors ivacaftor, lumacaftor-ivacaftor, tezacaftor-ivacaftor, elexacaftor-tezacaftor-ivacaftor----[1] 299 💬
44VX-659/tezacaftor/ivacaftor[2] Ivacaftor (Ivacaftor),
Tezacaftor		[2] Ivacaftor (Ivacaftor),
Tezacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
45VX-661 plus ivacaftor combination[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
46VX-661/ivacaftor[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
47VX-661/ivacaftor (VX-770) 100MG/150 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
48VX-661/ivacaftor 100 MG/ 150 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
49VX-661/ivacaftor 100MG/150 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
50VX-661/ivacaftor 100MG/150MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
51VX-661/ivacaftor 50 MG/ 75 MG[1] Ivacaftor (Ivacaftor)[1] Ivacaftor (Ivacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬