Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1[Leflunomide][1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 53 💬
2Leflunomide[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[14] 11, 40, 46, 49, 53, 54, 66, 107, 162, 223, 224, 270, 271, 300 💬
3Leflunomide (permitted, not necessary)[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
4Leflunomide 10 milligram (MG)[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
5Leflunomide 20 mg Tablets (Geneva Pharmaceutical)[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
6Leflunomide 20 mg+prednisone 0.5mg/kg/d[2] Leflunomide (Leflunomide),
Prednisone		[2] Prednisone ,
Leflunomide (Leflunomide) 💬 		[2] DHODH,
NR3C1 💬 		[2] Neuroactive ligand-receptor interaction, Pyrimidine metabolism 💬[2] 66, 223 💬
7Leflunomide 20Mg Tab[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
8Leflunomide 20mg/d[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 53 💬
9Leflunomide Mylan[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 53 💬
10Leflunomide plus Methotrexate[2] Leflunomide (Leflunomide),
Methotrexate		[3] Methotrexate ,
Leflunomide (Leflunomide),
Methotrexate sodium 💬 		[3] DHFR,
DHFR2,
DHODH 💬 		[4] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate, Pyrimidine metabolism 💬[1] 107 💬
11Leflunomide(LEF)[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[2] 40, 224 💬
12Leflunomide-Sulfasalazine-Hydroxychloroquine[3] Hydroxychloroquine,
Leflunomide (Leflunomide),
Sulfasalazine		[4] Sulfasalazine ,
Leflunomide (Leflunomide),
Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		[1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
13Methotrexate or leflunomide + sulfasalazine + hydroxychloroquine administration[4] Hydroxychloroquine,
Leflunomide (Leflunomide),
Methotrexate,
Sulfasalazine		[6] Methotrexate ,
Sulfasalazine ,
Leflunomide (Leflunomide),
Hydroxychloroquine sulfate ,
Methotrexate sodium ,
Hydroxychloroquine 💬 		[3] DHFR,
DHFR2,
DHODH 💬 		[4] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate, Pyrimidine metabolism 💬[1] 46 💬
14Study for the correlation of SNPs with efficacy and toxicity of Leflunomide in RA patients[1] Leflunomide (Leflunomide)[1] Leflunomide (Leflunomide) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬