Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Combination Product: EGCG 300 mg + Nintedanib[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85 💬
2Combination Product: EGCG 600 mg + Nintedanib[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85 💬
3L01XE31 - Nintedanib[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85 💬
4MNKD-201(Nintedanib DPI)[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85 💬
5NINTEDANIB[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[7] 51, 84, 85, 89, 227, 228, 331 💬
6Nintedanib 150 mg and 100 mg soft capsules[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 227 💬
7Nintedanib,Dextromethorphan[2] Dextromethorphan,
Nintedanib (Nintedanib esylate)		[5] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex ,
Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[14] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
KDR,
PDGFRA,
PDGFRB,
SIGMAR1 💬 		[54] Adherens junction, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, Glutamatergic synapse, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Huntington disease, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, Long-term potentiation, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prion disease, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Spinocerebellar ataxia, Systemic lupus erythematosus, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway, cAMP signaling pathway 💬[1] 85 💬
8Pirfenidone and nintedanib[2] Nintedanib (Nintedanib esylate),
Pirfenidone		[3] Pirfenidone ,
Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[14] CCL2,
FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
IL10,
IL1A,
IL1B,
IL6,
KDR,
PDGFRA,
PDGFRB,
TNF 💬 		[108] AGE-RAGE signaling pathway in diabetic complications, Adherens junction, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemokine signaling pathway, Choline metabolism in cancer, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, Efferocytosis, Endocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, IgSF CAM signaling, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Integrin signaling, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, Melanoma, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Phospholipase D signaling pathway, Prion disease, Prostate cancer, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85 💬
9Pirfenidone or nintedanib[2] Nintedanib (Nintedanib esylate),
Pirfenidone		[3] Pirfenidone ,
Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[14] CCL2,
FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
IL10,
IL1A,
IL1B,
IL6,
KDR,
PDGFRA,
PDGFRB,
TNF 💬 		[108] AGE-RAGE signaling pathway in diabetic complications, Adherens junction, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Cadherin signaling, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chagas disease, Chemokine signaling pathway, Choline metabolism in cancer, Coronavirus disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, Efferocytosis, Endocytosis, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, IgSF CAM signaling, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Integrin signaling, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, Melanoma, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Phospholipase D signaling pathway, Prion disease, Prostate cancer, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 85 💬
10Sub-Study: Nintedanib[1] Nintedanib (Nintedanib esylate)[2] Nintedanib esylate (Nintedanib esylate, Nintedanib ethanesulfonate, NINTEDANIB, NINTEDANIB CAPSULES, 100 MG AND 150 MG),
Nintedanib (Nintedanib) 💬 		[8] FGFR1,
FGFR2,
FGFR3,
FLT1,
FLT4,
KDR,
PDGFRA,
PDGFRB 💬 		[36] Adherens junction, Bladder cancer, Breast cancer, Cadherin signaling, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Gastric cancer, Glioma, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 85 💬