KEGG DRUG

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Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin)

[5] Digoxin,
Flurbiprofen,
Midazolam,
Montelukast,
Omeprazole

[5] Digoxin ,
Flurbiprofen ,
Omeprazole ,
Midazolam ,
Montelukast 💬

Name	Other Names
Digoxin	Digoxin (JP18/USP) Lanoxicaps (TN) Lanoxin (TN) DIGOX
Flurbiprofen	Flurbiprofen (JP18/USP/INN) Ansaid (TN)
Omeprazole	Omeprazole (JP18/USP/INN) Prilosec (TN)
Midazolam	Midazolam (JAN/USP/INN) Dormicum (TN) Buccolam (TN) Nayzilam (TN) N/A
Montelukast	Montelukast (INN) Brondilat (TN)

[25] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4,
ATP4A,
ATP4B,
CYSLTR1,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB ...

Name	Full Name
ATP1A1	ATPase Na+/K+ transporting subunit alpha 1
ATP1A2	ATPase Na+/K+ transporting subunit alpha 2
ATP1A3	ATPase Na+/K+ transporting subunit alpha 3
ATP1A4	ATPase Na+/K+ transporting subunit alpha 4
ATP4A	ATPase H+/K+ transporting subunit alpha
ATP4B	ATPase H+/K+ transporting subunit beta
CYSLTR1	cysteinyl leukotriene receptor 1
GABRA1	gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2	gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3	gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4	gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5	gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6	gamma-aminobutyric acid type A receptor subunit alpha6
GABRB1	gamma-aminobutyric acid type A receptor subunit beta1
GABRB2	gamma-aminobutyric acid type A receptor subunit beta2
GABRB3	gamma-aminobutyric acid type A receptor subunit beta3
GABRD	gamma-aminobutyric acid type A receptor subunit delta
GABRE	gamma-aminobutyric acid type A receptor subunit epsilon
GABRG1	gamma-aminobutyric acid type A receptor subunit gamma1
GABRG2	gamma-aminobutyric acid type A receptor subunit gamma2
GABRG3	gamma-aminobutyric acid type A receptor subunit gamma3
GABRP	gamma-aminobutyric acid type A receptor subunit pi
GABRQ	gamma-aminobutyric acid type A receptor subunit theta
PTGS1	prostaglandin-endoperoxide synthase 1
PTGS2	prostaglandin-endoperoxide synthase 2

[49] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regula ...

[1] 46 💬

Clartihromycin, amoxicillin, and omeprazole

[2] Amoxicillin,
Omeprazole

[3] Amoxicillin ,
Omeprazole ,
Amoxicillin 💬

Name	Other Names
Amoxicillin	Amoxicillin (USP) Amoxicillin hydrate (JP18) Amoxicilline (INN) Amoxicillin trihydrate Amoxil (TN) Dispermox (TN) Pasetocin (TN) AMOXICILLIN 500 MG
Omeprazole	Omeprazole (JP18/USP/INN) Prilosec (TN)
Amoxicillin	Amoxicillin (INN) AMPC Amoxicillin (TN)

[2] ATP4A,
ATP4B 💬

[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphoryl ...

[1] 6 💬

Diclofenac + Omeprazole

[2] Diclofenac,
Omeprazole

[2] Omeprazole ,
Diclofenac 💬

[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬

[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...

[1] 46 💬

Dimebon + Omeprazole

[2] Latrepirdine,
Omeprazole

[2] Omeprazole ,
Latrepirdine 💬

[8] ACHE,
ATP4A,
ATP4B,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬

Name	Full Name
ACHE	acetylcholinesterase (Cartwright blood group)
ATP4A	ATPase H+/K+ transporting subunit alpha
ATP4B	ATPase H+/K+ transporting subunit beta
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

[26] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium si ...

[1] 8 💬

Naproxen 500 mg tablets (PN 200 minus omeprazole)

[2] Naproxen,
Omeprazole

[2] Naproxen ,
Omeprazole 💬

[4] ATP4A,
ATP4B,
PTGS1,
PTGS2 💬

[26] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemi ...

[2] 46, 271 💬

Omeprazole

[1] Omeprazole

[1] Omeprazole 💬

[2] ATP4A,
ATP4B 💬

[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphoryl ...

[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
225	Congenital nephrogenic diabetes insipidus
271	Ankylosing spondylitis
282	Congenital dyserythropoietic anemia
294	Congenital diaphragmatic hernia
298	Hereditary pancreatitis
299	Cystic fibrosis