Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1FDC macitentan/tadalafil
(Opsumit, OPSUMIT)		[2] Macitentan,
Tadalafil		[2] Tadalafil ,
Macitentan (Opsumit, OPSUMIT) 💬 		[3] EDNRA,
EDNRB,
PDE5 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
2Macitentan
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 51, 85, 86, 88, 210 💬
3Macitentan 10 MG
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 86, 88 💬
4Macitentan 10MG
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 88 💬
5Macitentan 3 MG
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
6Macitentan 37.5 MG
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
7Macitentan 3MG
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
8Macitentan 75 MG
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
9Macitentan compresse
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
10Macitentan group
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
11Macitentan tablets
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
12Macitentan tablets
(Opsumit, OPSUMIT)		[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
13Observational study with patients treated with tracleer, ventavis, veletri, opsumit and/or uptravi----[1] 86 💬
14Opsumit[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬
15Opsumit 10 MG tablet----[1] 51 💬
16Opsumit®[1] Macitentan[1] Macitentan (Opsumit, OPSUMIT) 💬 [2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 86, 88 💬