KEGG DRUG

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Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

ATG+cyclosporine
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[1] 60 💬

ATG+Rapamune+cyclosporine
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[1] 60 💬

Busulfan, fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine.
(Restasis ...

[4] Busulfan,
Cyclophosphamide,
Cyclosporine (Restasis),
Fludarabine

[5] Cyclosporine (Restasis(TN)),
Busulfan ,
Cyclophosphamide ,
Cyclophosphamide ,
Fludarab ...

Name	Other Names
Cyclosporine	Cyclosporine (USP) Ciclosporin (JP18) Gengraf (TN) Neoral (TN) Restasis (TN) Sandimmune (TN) CEQUA RESTASIS MULTIDOSE VERKAZIA CYCLOSPORINE, MODFIED
Busulfan	Busulfan (JP18/USP/INN) Myleran (TN) BUSULFEX
Cyclophosphamide	Cyclophosphamide (USP) Cyclophosphamide hydrate (JP18) Cytoxan (TN) Neosar (TN)
Cyclophosphamide	Cyclophosphamide (INN) Cyclophosphamide (TN) Cytoxan (TN)
Fludarabine	Fludarabine (INN) Fluradosa (TN)

[6] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2,
RRM1 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta
RRM1	ribonucleotide reductase catalytic subunit M1

[39] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[2] 60, 285 💬

Cyclophosphamide,cyclosporine A
(Restasis (TN))

[2] Cyclophosphamide,
Cyclosporine (Restasis)

[3] Cyclosporine (Restasis (TN)),
Cyclophosphamide ,
Cyclophosphamide 💬

Name	Other Names
Cyclosporine	Cyclosporine (USP) Ciclosporin (JP18) Gengraf (TN) Neoral (TN) Restasis (TN) Sandimmune (TN) CEQUA RESTASIS MULTIDOSE VERKAZIA CYCLOSPORINE, MODFIED
Cyclophosphamide	Cyclophosphamide (USP) Cyclophosphamide hydrate (JP18) Cytoxan (TN) Neosar (TN)
Cyclophosphamide	Cyclophosphamide (INN) Cyclophosphamide (TN) Cytoxan (TN)

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[1] 60 💬

Cyclosporine
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, ...

Disease ID	Name
11	Myasthenia gravis
19	Lysosomal storage disease
20	Adrenoleukodystrophy
28	Systemic amyloidosis
36	Epidermolysis bullosa
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
53	Sjogren syndrome
56	Behcet disease
58	Hypertrophic cardiomyopathy
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
90	Retinitis pigmentosa
95	Autoimmune hepatitis
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
162	Pemphigoid
164	Oculocutaneous albinism
222	Primary nephrotic syndrome
226	Interstitial cystitis with Hunners ulcer
228	Bronchiolitis obliterans
234	Peroxisomal disease (except Adrenoleukodystrophy)
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
302	Leber hereditary optic neuropathy

Cyclosporine (Gengraf )
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[1] 60 💬

Cyclosporine (USAN)
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[1] 97 💬

Cyclosporine 0.09% Ophthalmic Solution
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[1] 53 💬

Cyclosporine 5 mg/kg bid days 0-14
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[2] 38, 39 💬

Cyclosporine A
(Restasis (TN))

[1] Cyclosporine (Restasis)

[1] Cyclosporine (Restasis (TN)) 💬

[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬

Name	Full Name
PPP3CA	protein phosphatase 3 catalytic subunit alpha
PPP3CB	protein phosphatase 3 catalytic subunit beta
PPP3CC	protein phosphatase 3 catalytic subunit gamma
PPP3R1	protein phosphatase 3 regulatory subunit B, alpha
PPP3R2	protein phosphatase 3 regulatory subunit B, beta

[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell ...

[11] 19, 20, 36, 49, 50, 53, 58, 60, 107, 234, 283 💬

Disease ID	Name
19	Lysosomal storage disease
20	Adrenoleukodystrophy
36	Epidermolysis bullosa
49	Systemic lupus erythematosus
50	Dermatomyositis
53	Sjogren syndrome
58	Hypertrophic cardiomyopathy
60	Aplastic anemia
107	Juvenile idiopathic arthritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
283	Acquired pure red cell aplasia

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