About Icons

Icon	Function
💬	A pop-up explanation appears when you mouse-over the text beside this icon. Also, an explanation window appears when you click this icon.
	The links beside this icon are links to external sites.
	Clicking this icon sorts the table by the item with this icon (Numerical or alphabetical order). Each click toggles between ascending and descending order.
	A text longer than 100 characters is fully displayed or collapsed.
	The contents of the displayed table are downloaded as a file named "table.csv".

Drug Description in Trials / DrugBank / KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[1] Sotatercept (Sotatercept)

[1] Sotatercept (Sotatercept, sotatercept-csrk) 💬

[1] ACVR2A 💬

[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[2] 86, 284 💬

2

Sotatercept - 45 mg/vial

[1] Sotatercept (Sotatercept)

[1] Sotatercept (Sotatercept, sotatercept-csrk) 💬

[1] ACVR2A 💬

[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[1] 86 💬

3

Sotatercept - 60 mg/vial

[1] Sotatercept (Sotatercept)

[1] Sotatercept (Sotatercept, sotatercept-csrk) 💬

[1] ACVR2A 💬

[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[1] 86 💬

4

Sotatercept - 60 mg/vialProduct Code: ACE-011 / MK-7962 Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962 Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg milligram(s)Concentration type: equalConcentration number: 72.5-Product Name: Sotatercept - 45 mg/vialProduct Code: ACE-011 / MK-7962 Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962 Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg milligram(s)Concentration type: equalConcentration number: 55-

[1] Sotatercept (Sotatercept)

[1] Sotatercept (Sotatercept, sotatercept-csrk) 💬

[1] ACVR2A 💬

[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[1] 86 💬

5

Sotatercept - 60 mg/vialProduct Code: ACE-011 / MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 72.5-Product Name: Sotatercept - 45 mg/vialProduct Code: ACE-011 / MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 55-

[1] Sotatercept (Sotatercept)

[1] Sotatercept (Sotatercept, sotatercept-csrk) 💬

[1] ACVR2A 💬

[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[1] 86 💬

6

Sotatercept 0.3 mg/kg escalating to 0.7 mg/kg

[1] Sotatercept (Sotatercept)

[1] Sotatercept (Sotatercept, sotatercept-csrk) 💬

[1] ACVR2A 💬

[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[1] 86 💬

7

Sotatercept with prednisone boost

[2] Prednisone,
Sotatercept (Sotatercept)

[2] Prednisone ,
Sotatercept (Sotatercept, sotatercept-csrk) 💬

[2] ACVR2A,
NR3C1 💬

[5] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Neuroactive ligand-receptor interaction, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬

[1] 284 💬

8

SotaterceptProduct Code: ACE-011 / MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011 / MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 50-Pharmaceutical form of the placebo: Lyophilisate for solution for injectionRoute of administration of the placebo: Subcutaneous use

-

-

-

-

[1] 86 💬

9

SotaterceptProduct Code: ACE-011/MK-7962Pharmaceutical Form: Lyophilisate for solution for injectionINN or Proposed INN: SOTATERCEPTCAS Number: 1001080-50-7Current Sponsor code: ACE-011/MK-7962Other descriptive name: ActRIIA-IgG1FcConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 50-Pharmaceutical form of the placebo: Lyophilisate for solution for injectionRoute of administration of the placebo: Subcutaneous use

-

-

-

-

[1] 86 💬