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Drug Description in Trials / DrugBank / KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Ambrisentan plus Spironolactone

[2] Ambrisentan,
Spironolactone (Spironolactone)

[2] Spironolactone (Spironolactone),
Ambrisentan 💬

[2] EDNRA,
NR3C2 💬

[8] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 86 💬

2

Ramipril Tritace®, Carvedilol Carvid®,and Spironolactone Aldactone®

[3] Carvedilol,
Ramipril,
Spironolactone (Spironolactone)

[4] Carvedilol ,
Ramipril ,
Spironolactone (Spironolactone),
Carvedilol phosphate 💬

[7] ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬

Name	Full Name
ACE	angiotensin-converting enzyme isoform 1 precursor
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
NR3C2	mineralocorticoid receptor isoform 1

[21] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Hypertrophic cardiomyopathy, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 57 💬

3

[1] Spironolactone (Spironolactone)

[1] Spironolactone (Spironolactone) 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
113	Muscular dystrophy
210	Single Ventricle
214	Pulmonary atresia with ventricular septum defect
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
225	Congenital nephrogenic diabetes insipidus

4

Spironolactone (drug)

[1] Spironolactone (Spironolactone)

[1] Spironolactone (Spironolactone) 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 210 💬

5

Spironolactone and conivaptan

[2] Conivaptan,
Spironolactone (Spironolactone)

[3] Spironolactone (Spironolactone),
Conivaptan hydrochloride ,
Conivaptan 💬

[3] AVPR1A,
AVPR2,
NR3C2 💬

[7] Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬

[1] 86 💬

6

Spironolactone captopril carvedilol

[3] Captopril,
Carvedilol,
Spironolactone (Spironolactone)

[4] Captopril ,
Carvedilol ,
Spironolactone (Spironolactone),
Carvedilol phosphate 💬

[7] ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬

Name	Full Name
ACE	angiotensin-converting enzyme isoform 1 precursor
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
ADRB2	beta-2 adrenergic receptor
NR3C2	mineralocorticoid receptor isoform 1

[21] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Hypertrophic cardiomyopathy, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 86 💬

7

Spironolactone Mylan 25 mg comprimé pelliculé sécable

[1] Spironolactone (Spironolactone)

[1] Spironolactone (Spironolactone) 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 46 💬

8

Spironolactone or Finerenone

[2] Finerenone,
Spironolactone (Spironolactone)

[2] Spironolactone (Spironolactone),
Finerenone 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 218 💬

9

Treatment with Dapagliflozin followed by Spironolactone followed by their combination

[2] Dapagliflozin,
Spironolactone (Spironolactone)

[2] Spironolactone (Spironolactone),
Dapagliflozin 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 218 💬

10

Treatment with Spironolactone followed by Dapagliflozin followed by their combination

[2] Dapagliflozin,
Spironolactone (Spironolactone)

[2] Spironolactone (Spironolactone),
Dapagliflozin 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 218 💬