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Drug Description in Trials / DrugBank / KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

AMIODARONE
(D00636)

[2] Amiodarone hydrochloride (D00636),
Amiodarone 💬

[17] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
KCND3	A-type voltage-gated potassium channel KCND3 isoform 1
KCNJ11	ATP-sensitive inward rectifier potassium channel 11 isoform 1
KCNJ12	ATP-sensitive inward rectifier potassium channel 12
KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform 1
KCNJ5	G protein-activated inward rectifier potassium channel 4
KCNJ8	ATP-sensitive inward rectifier potassium channel 8
KCNQ1	potassium voltage-gated channel subfamily KQT member 1 isoform 1
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[36] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, IgSF CAM signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[3] 28, 67, 127 💬

2

Amiodarone Hydrochloride Tablets
(D00636)

[2] Amiodarone hydrochloride (D00636),
Amiodarone 💬

[17] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
KCND3	A-type voltage-gated potassium channel KCND3 isoform 1
KCNJ11	ATP-sensitive inward rectifier potassium channel 11 isoform 1
KCNJ12	ATP-sensitive inward rectifier potassium channel 12
KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform 1
KCNJ5	G protein-activated inward rectifier potassium channel 4
KCNJ8	ATP-sensitive inward rectifier potassium channel 8
KCNQ1	potassium voltage-gated channel subfamily KQT member 1 isoform 1
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[36] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, IgSF CAM signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 67 💬

3

Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias)
(D00636)

[2] Amiodarone hydrochloride (D00636),
Amiodarone 💬

[17] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
KCND3	A-type voltage-gated potassium channel KCND3 isoform 1
KCNJ11	ATP-sensitive inward rectifier potassium channel 11 isoform 1
KCNJ12	ATP-sensitive inward rectifier potassium channel 12
KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform 1
KCNJ5	G protein-activated inward rectifier potassium channel 4
KCNJ8	ATP-sensitive inward rectifier potassium channel 8
KCNQ1	potassium voltage-gated channel subfamily KQT member 1 isoform 1
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[36] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, IgSF CAM signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 28 💬

4

Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus EGCG
(D00636)

[2] Amiodarone hydrochloride (D00636),
Amiodarone 💬

[17] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬

Name	Full Name
ADRA1A	alpha-1A adrenergic receptor isoform 1
ADRA1B	alpha-1B adrenergic receptor
ADRA1D	alpha-1D adrenergic receptor
ADRB1	beta-1 adrenergic receptor
KCND3	A-type voltage-gated potassium channel KCND3 isoform 1
KCNJ11	ATP-sensitive inward rectifier potassium channel 11 isoform 1
KCNJ12	ATP-sensitive inward rectifier potassium channel 12
KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform 1
KCNJ5	G protein-activated inward rectifier potassium channel 4
KCNJ8	ATP-sensitive inward rectifier potassium channel 8
KCNQ1	potassium voltage-gated channel subfamily KQT member 1 isoform 1
SCN1A	sodium channel protein type 1 subunit alpha isoform 1
SCN2A	sodium channel protein type 2 subunit alpha isoform 1
SCN3A	sodium channel protein type 3 subunit alpha isoform 2
SCN5A	sodium channel protein type 5 subunit alpha isoform a
SCN8A	sodium channel protein type 8 subunit alpha isoform 3
SCN9A	sodium channel protein type 9 subunit alpha isoform 2

[36] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Cadherin signaling, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, IgSF CAM signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[1] 28 💬