Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1[Leflunomide]
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 53 💬
2Leflunomide
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[14] 11, 40, 46, 49, 53, 54, 66, 107, 162, 223, 224, 270, 271, 300 💬
3Leflunomide (permitted, not necessary)
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
4Leflunomide 10 milligram (MG)
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
5Leflunomide 20 mg Tablets (Geneva Pharmaceutical)
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
6Leflunomide 20 mg+prednisone 0.5mg/kg/d
(D00749)		[2] Leflunomide,
Prednisone		[2] Prednisone ,
Leflunomide (D00749) 💬 		[2] DHODH,
NR3C1 💬 		[2] Neuroactive ligand-receptor interaction, Pyrimidine metabolism 💬[2] 66, 223 💬
7Leflunomide 20Mg Tab
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
8Leflunomide 20mg/d
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 53 💬
9Leflunomide Mylan
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 53 💬
10Leflunomide plus Methotrexate
(D00749)		[2] Leflunomide,
Methotrexate		[3] Methotrexate ,
Leflunomide (D00749),
Methotrexate sodium 💬 		[3] DHFR,
DHFR2,
DHODH 💬 		[4] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate, Pyrimidine metabolism 💬[1] 107 💬
11Leflunomide(LEF)
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[2] 40, 224 💬
12Leflunomide-Sulfasalazine-Hydroxychloroquine
(D00749)		[3] Hydroxychloroquine,
Leflunomide,
Sulfasalazine		[4] Sulfasalazine ,
Leflunomide (D00749),
Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		[1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬
13Methotrexate or leflunomide + sulfasalazine + hydroxychloroquine administration
(D00749)		[4] Hydroxychloroquine,
Leflunomide,
Methotrexate,
Sulfasalazine		[6] Methotrexate ,
Sulfasalazine ,
Leflunomide (D00749),
Hydroxychloroquine sulfate ,
Methotrexate sodium ,
Hydroxychloroquine 💬 		[3] DHFR,
DHFR2,
DHODH 💬 		[4] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate, Pyrimidine metabolism 💬[1] 46 💬
14Study for the correlation of SNPs with efficacy and toxicity of Leflunomide in RA patients
(D00749)		[1] Leflunomide[1] Leflunomide (D00749) 💬 [1] DHODH 💬 [1] Pyrimidine metabolism 💬[1] 46 💬