Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(D02008)		[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[6] Bosentan ,
Tadalafil (D02008),
Sildenafil citrate ,
Bosentan ,
Sildenafil ,
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
2FDC macitentan/tadalafil
(D02008)		[2] Macitentan,
Tadalafil		[2] Tadalafil (D02008),
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
3TADALAFIL
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[8] 6, 51, 75, 77, 84, 86, 113, 210 💬
4Tadalafil 20 MG
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬
5Tadalafil 20 mg film-coated tablets
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
6Tadalafil 40 mg
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
7Tadalafil and ambrisentan upfront combination therapy
(D02008)		[2] Ambrisentan,
Tadalafil		[2] Tadalafil (D02008),
Ambrisentan 💬 		[2] EDNRA,
PDE5A 💬 		[8] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
8Tadalafil and Sildenafil
(D02008)		[2] Sildenafil,
Tadalafil		[3] Tadalafil (D02008),
Sildenafil citrate ,
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬
9Tadalafil Citrate
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210 💬
10Tadalafil mimic
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
11Tadalafil oral suspension
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
12Tadalafil- Tablet or Oral suspension
(D02008)		[1] Tadalafil[1] Tadalafil (D02008) 💬 [1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬