Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
120 mg sildenafil citrate by mouth
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
25% sildenafil cream
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 50 💬
3Access program - sildenafil citrate, Viagra, Revatio
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
4Duo-Therapy with Sildenafil + Bosentan
(D02229)		[2] Bosentan,
Sildenafil		[4] Bosentan ,
Sildenafil citrate (D02229),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
5ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(D02229)		[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[6] Bosentan ,
Tadalafil ,
Sildenafil citrate (D02229),
Bosentan ,
Sildenafil ,
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
6G04BE03- Sildenafil - sildenafil (citrato)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
7Mono-Therapy with Sildenafil
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
8Oral sildenafil
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
9Other: Standard of Care Sildenafil
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 90, 301 💬
10Sildenafil
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
11Sildenafil (50 mg)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85 💬
12Sildenafil (Acute-1 hour)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
13Sildenafil (as citrate)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
14Sildenafil (Revatio) 20 mg TID
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
15Sildenafil (Subchronic-4 weeks)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
16Sildenafil 10mg oral tablet (participants <20kg), or 20mg oral tablet (participants =20kg)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210 💬
17Sildenafil 20 mg tablets
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 278 💬
18Sildenafil 20mg
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
19Sildenafil 20mg and Bosentan 62.5mg
(D02229)		[2] Bosentan,
Sildenafil		[4] Bosentan ,
Sildenafil citrate (D02229),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
20Sildenafil 40mg oral capsule
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
21Sildenafil and Losartan
(D02229)		[2] Losartan,
Sildenafil		[4] Losartan potassium ,
Sildenafil citrate (D02229),
Losartan ,
Sildenafil 💬 		[2] AGTR1,
PDE5A 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85 💬
22Sildenafil by injection
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210 💬
23SILDENAFIL CITRATE
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225 💬
24Sildenafil citrate (UK-92,480)
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
25Sildenafil Filmtabletten
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
26Sildenafil Oral Suspension
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 294 💬
27Sildenafil singly or in association with Bosentan
(D02229)		[2] Bosentan,
Sildenafil		[4] Bosentan ,
Sildenafil citrate (D02229),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
28Sildenafil therapy
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 51 💬
29Sitaxsentan and Sildenafil
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
30Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth
(D02229)		[1] Sildenafil[2] Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
31Tadalafil and Sildenafil
(D02229)		[2] Sildenafil,
Tadalafil		[3] Tadalafil ,
Sildenafil citrate (D02229),
Sildenafil 💬 		[1] PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬