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KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

DIMETHYL FUMARATE
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[5] 13, 20, 51, 86, 296 💬

Dimethyl Fumarate (DMF)
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[3] 13, 51, 86 💬

Dimethyl fumarate 240 mg
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[1] 13 💬

Dimethyl Fumarate 240 MG [Tecfidera]
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[1] 13 💬

Dimethyl fumarate [DMF]
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[1] 13 💬

Dimethyl Fumarate Enteric-coated Capsules
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[1] 13 💬

Interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fingolimod, ponesimod, rituximab, ocrelizumab, ofatumumab, natalizumab
(D03846)

[12] Acetate,
Alemtuzumab,
Cladribine,
Dimethyl fumarate,
Fingolimod,
Glatiramer,
Natalizumab,
Ocrelizumab,
Ofatumumab,
Ponesimod,
Rituximab,
Teriflunomide

[13] Cladribine ,
Alemtuzumab ,
Rituximab ,
Dimethyl fumarate (D03846),
Fingolimod hydrochloride ,
Glatiramer acetate ,
Ocrelizumab ,
Natalizumab ,
Ofatumumab ,
Fingolimod ,
Teriflunomide ,
Ponesimod ,
Fingolimod lauryl sulfate 💬

Name	Other Names
Cladribine	Leustatin Mavenclad
Alemtuzumab	Campath Lemtrada
Rituximab	Rituximab-abbs Rituximab-pvvr Rituximab-arrx Rituxan Riabni Truximab RUXIENCE TRUXIMA
Dimethyl fumarate	Tecfidera
Fingolimod hydrochloride	Gilenya FINGOLIMOD
Glatiramer acetate	Copaxone GLATOPA
Ocrelizumab	Ocrevus OCREVUS ZUNOVO
Natalizumab	Natalizumab-sztn Tysabri Tyruko
Ofatumumab	Arzerra Kesimpta
Fingolimod	Gilenya
Teriflunomide	Aubagio
Ponesimod	Ponvory
Fingolimod lauryl sulfate	Tascenso TASCENSO ODT

[26] DHODH,
HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G,
ITGA4,
KEAP1,
MS4A1,
RRM1,
S1PR1 💬

Name	Full Name
DHODH	dihydroorotate dehydrogenase (quinone), mitochondrial
HLA-A	HLA class I histocompatibility antigen, A alpha chain isoform A*03:01:01:01 precursor
HLA-B	major histocompatibility complex, class I, B precursor
HLA-C	HLA class I histocompatibility antigen, C alpha chain precursor
HLA-DMA	HLA class II histocompatibility antigen, DM alpha chain precursor
HLA-DMB	HLA class II histocompatibility antigen, DM beta chain precursor
HLA-DOA	HLA class II histocompatibility antigen, DO alpha chain precursor
HLA-DOB	HLA class II histocompatibility antigen, DO beta chain precursor
HLA-DPA1	HLA class II histocompatibility antigen, DP alpha 1 chain precursor
HLA-DPB1	HLA class II histocompatibility antigen, DP beta 1 chain precursor
HLA-DQA1	HLA class II histocompatibility antigen, DQ alpha 1 chain precursor
HLA-DQA2	HLA class II histocompatibility antigen, DQ alpha 2 chain precursor
HLA-DQB1	HLA class II histocompatibility antigen, DQ beta 1 chain isoform 2 precursor
HLA-DRA	HLA class II histocompatibility antigen, DR alpha chain precursor
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 precursor
HLA-DRB3	major histocompatibility complex, class II, DR beta 3 precursor
HLA-DRB4	major histocompatibility complex, class II, DR beta 4 precursor
HLA-DRB5	major histocompatibility complex, class II, DR beta 5 precursor
HLA-E	HLA class I histocompatibility antigen, alpha chain E precursor
HLA-F	HLA class I histocompatibility antigen, alpha chain F isoform 2 precursor
HLA-G	HLA class I histocompatibility antigen, alpha chain G isoform 2 precursor
ITGA4	integrin alpha-4 isoform 1 preproprotein
KEAP1	kelch-like ECH-associated protein 1
MS4A1	B-lymphocyte antigen CD20
RRM1	ribonucleoside-diphosphate reductase large subunit isoform 1
S1PR1	sphingosine 1-phosphate receptor 1

[58] Allograft rejection, Antigen processing and presentation, Arrhythmogenic right ventricular cardiomyopathy, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cellular senescence, Chemical carcinogenesis - reactive oxygen species, Cytoskeleton in muscle cells, Dilated cardiomyopathy, Drug metabolism - other enzymes, ECM-receptor interaction, Efferocytosis, Endocytosis, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Glutathione metabolism, Graft-versus-host disease, Hematopoietic cell lineage, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IgSF CAM signaling, Inflammatory bowel disease, Influenza A, Integrin signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Pathways in cancer, Phagocytosis, Purine metabolism, Pyrimidine metabolism, Regulation of actin cytoskeleton, Rheumatoid arthritis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Ubiquitin mediated proteolysis, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬

[1] 13 💬

Other: dimethyl fumarate (DMF)
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[1] 13 💬

Platform therapies (Dimethyl Fumarate, Teriflunomide, Glatiramer Acetate, Beta-interferons)
(D03846)

[4] Acetate,
Dimethyl fumarate,
Glatiramer,
Teriflunomide

[3] Dimethyl fumarate (D03846),
Glatiramer acetate ,
Teriflunomide 💬

[22] DHODH,
HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G,
KEAP1 💬

Name	Full Name
DHODH	dihydroorotate dehydrogenase (quinone), mitochondrial
HLA-A	HLA class I histocompatibility antigen, A alpha chain isoform A*03:01:01:01 precursor
HLA-B	major histocompatibility complex, class I, B precursor
HLA-C	HLA class I histocompatibility antigen, C alpha chain precursor
HLA-DMA	HLA class II histocompatibility antigen, DM alpha chain precursor
HLA-DMB	HLA class II histocompatibility antigen, DM beta chain precursor
HLA-DOA	HLA class II histocompatibility antigen, DO alpha chain precursor
HLA-DOB	HLA class II histocompatibility antigen, DO beta chain precursor
HLA-DPA1	HLA class II histocompatibility antigen, DP alpha 1 chain precursor
HLA-DPB1	HLA class II histocompatibility antigen, DP beta 1 chain precursor
HLA-DQA1	HLA class II histocompatibility antigen, DQ alpha 1 chain precursor
HLA-DQA2	HLA class II histocompatibility antigen, DQ alpha 2 chain precursor
HLA-DQB1	HLA class II histocompatibility antigen, DQ beta 1 chain isoform 2 precursor
HLA-DRA	HLA class II histocompatibility antigen, DR alpha chain precursor
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 precursor
HLA-DRB3	major histocompatibility complex, class II, DR beta 3 precursor
HLA-DRB4	major histocompatibility complex, class II, DR beta 4 precursor
HLA-DRB5	major histocompatibility complex, class II, DR beta 5 precursor
HLA-E	HLA class I histocompatibility antigen, alpha chain E precursor
HLA-F	HLA class I histocompatibility antigen, alpha chain F isoform 2 precursor
HLA-G	HLA class I histocompatibility antigen, alpha chain G isoform 2 precursor
KEAP1	kelch-like ECH-associated protein 1

[39] Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Cellular senescence, Chemical carcinogenesis - reactive oxygen species, Endocytosis, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Parkinson disease, Pathways in cancer, Phagocytosis, Pyrimidine metabolism, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Ubiquitin mediated proteolysis, Viral carcinogenesis, Viral myocarditis 💬

[1] 13 💬

Tecifdera (dimethyl fumarate)
(D03846)

[1] Dimethyl fumarate

[1] Dimethyl fumarate (D03846) 💬

[1] KEAP1 💬

[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬

[1] 13 💬