Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1150-mg IVACAFTOR
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
2150mg IVACAFTOR
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
375-mg IVACAFTOR
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
4CF patients with a G551D mutation and treated with Ivacaftor
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
5Deuterated Ivacaftor
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
6Elexacaftor / Ivacaftor / Tezacaftor
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
7Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
8Elexacaftor, Tezacaftor, Ivacaftor
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
9Elexacaftor-tezacaftor-ivacaftor exposure
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
10Elexacaftor-tezacaftor-ivacaftor treatment
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
11Elexacaftor/tezacaftor/ivacaftor
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
12Ivacaftor
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[3] 298, 299, 340 💬
13Ivacaftor (proposed INN)
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
14Ivacaftor 125mg tablet
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
15Ivacaftor 150 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
16Ivacaftor 150 MG (milligrams)
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[2] 298, 299 💬
17Ivacaftor 150 mg or 250 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
18Ivacaftor 25 mg/75 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
19IVACAFTOR 59,5mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
20IVACAFTOR 59.5mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
21Ivacaftor 75 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
22Ivacaftor 75 mg/150 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
23IVACAFTOR 75mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
24Ivacaftor and Symdeko
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
25Ivacaftor Exposed
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
26Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(D09916)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
27Ivacaftor+lumacaftor
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
28Ivacaftor/Ataluren
(D09916)		[2] Ataluren,
Ivacaftor		[2] Ataluren ,
Ivacaftor (D09916) 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
29Ivacaftor/Kalydeco
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
30Lumacaftor / ivacaftor
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
31Lumacaftor plus Ivacaftor
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
32Lumacaftor Plus Ivacaftor Combination
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
33Lumacaftor, Ivacaftor Drug Combination
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
34Lumacaftor-ivacaftor
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
35Lumacaftor-Ivacaftor treatment
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
36Lumacaftor/Ivacaftor
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
37Lumacaftor/ivacaftor 100mg/125mg tablets
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
38Lumacaftor/ivacaftor 200mg/125mg
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
39Lumacaftor/ivacaftor 200mg/125mg tablets
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
40Lumacaftor/ivacaftor 200mg/83mg tablet
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
41Orkambi: contains lumacaftor and ivacaftor
(D09916)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor (D09916),
Lumacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
42Tezacaftor/Ivacaftor
(D09916)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor (D09916),
Tezacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
43Tezacaftor/Ivacaftor + Ivacaftor
(D09916)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor (D09916),
Tezacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
44Tezacaftor/Ivacaftor 100mg/150mg
(D09916)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor (D09916),
Tezacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
45Tezacaftor/Ivacaftor/100mg/150mg
(D09916)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor (D09916),
Tezacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
46Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor, Vanzacaftor-Tezacaftor-Deutivacaftor
(D09916)		[6] Deutivacaftor,
Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor,
Vanzacaftor		[7] Ivacaftor (D09916),
Lumacaftor ,
Tezacaftor ,
Deutivacaftor ,
Elexacaftor ,
Vanzacaftor ,
Vanzacaftor calcium 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
47VX-659/Tezacaftor/Ivacaftor
(D09916)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor (D09916),
Tezacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
48VX-661 Plus Ivacaftor Combination
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
49VX-661/Ivacaftor
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
50VX-661/ivacaftor (VX-770) 100mg/150 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
51VX-661/ivacaftor 100 mg/ 150 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
52VX-661/ivacaftor 100mg/150 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
53VX-661/ivacaftor 100mg/150mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
54VX-661/ivacaftor 50 mg/ 75 mg
(D09916)		[1] Ivacaftor[1] Ivacaftor (D09916) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬