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Drug Description in Trials / DrugBank / KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

150-MG ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

2

150MG ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

3

75-MG ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

4

CF patients with A G551D mutation and treated with ivacaftor
(D09916)

-

-

-

-

[1] 299 💬

5

Deuterated ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

6

Elexacaftor / ivacaftor / tezacaftor
(D09916)

[1] Elexacaftor

[1] Elexacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

7

Elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG, 2 tablets each morning + ivacaftor 150 MG ONE tablet each evening
(D09916)

[1] Elexacaftor

[1] Elexacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

8

Elexacaftor-tezacaftor-ivacaftor exposure
(D09916)

[1] Elexacaftor

[1] Elexacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

9

Elexacaftor-tezacaftor-ivacaftor treatment
(D09916)

[1] Elexacaftor

[1] Elexacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

10

Elexacaftor/tezacaftor/ivacaftor
(D09916)

[3] Elexacaftor,
Ivacaftor,
Tezacaftor

[3] Ivacaftor (D09916),
Tezacaftor ,
Elexacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

11

Ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[2] 299, 340 💬

12

Ivacaftor 125MG tablet
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

13

Ivacaftor 150 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

14

Ivacaftor 150 MG or 250 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

15

Ivacaftor 25 MG/75 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

16

Ivacaftor 59,5MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

17

Ivacaftor 59.5MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

18

Ivacaftor 75 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

19

Ivacaftor 75 MG/150 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

20

Ivacaftor 75MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

21

Ivacaftor and symdeko
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

22

Ivacaftor exposed
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

23

Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

24

Ivacaftor+lumacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

25

Ivacaftor/ataluren
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

26

Ivacaftor/kalydeco
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

27

Lumacaftor / ivacaftor
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

28

Lumacaftor plus ivacaftor
(D09916)

[1] Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

29

Lumacaftor plus ivacaftor combination
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

30

Lumacaftor, ivacaftor drug combination
(D09916)

[1] Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

31

Lumacaftor-ivacaftor
(D09916)

[1] Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

32

Lumacaftor-ivacaftor treatment
(D09916)

[1] Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

33

Lumacaftor/ivacaftor
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

34

Lumacaftor/ivacaftor 100MG/125MG tablets
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

35

Lumacaftor/ivacaftor 200MG/125MG
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

36

Lumacaftor/ivacaftor 200MG/125MG tablets
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

37

Lumacaftor/ivacaftor 200MG/83MG tablet
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

38

Orkambi: contains lumacaftor and ivacaftor
(D09916)

[2] Ivacaftor,
Lumacaftor

[2] Ivacaftor (D09916),
Lumacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

39

Tezacaftor/ivacaftor
(D09916)

[2] Ivacaftor,
Tezacaftor

[2] Ivacaftor (D09916),
Tezacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

40

Tezacaftor/ivacaftor + ivacaftor
(D09916)

[1] Tezacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

41

Tezacaftor/ivacaftor 100MG/150MG
(D09916)

[2] Ivacaftor,
Tezacaftor

[2] Ivacaftor (D09916),
Tezacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

42

Tezacaftor/ivacaftor/100MG/150MG
(D09916)

[2] Ivacaftor,
Tezacaftor

[2] Ivacaftor (D09916),
Tezacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

43

Treatment with cystic fibrosis transmembrane regulator (cftr) modualtors ivacaftor, lumacaftor-ivacaftor, tezacaftor-ivacaftor, elexacaftor-tezacaftor-ivacaftor
(D09916)

-

-

-

-

[1] 299 💬

44

VX-659/tezacaftor/ivacaftor
(D09916)

[2] Ivacaftor,
Tezacaftor

[2] Ivacaftor (D09916),
Tezacaftor 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

45

VX-661 plus ivacaftor combination
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

46

VX-661/ivacaftor
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

47

VX-661/ivacaftor (VX-770) 100MG/150 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

48

VX-661/ivacaftor 100 MG/ 150 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

49

VX-661/ivacaftor 100MG/150 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

50

VX-661/ivacaftor 100MG/150MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬

51

VX-661/ivacaftor 50 MG/ 75 MG
(D09916)

[1] Ivacaftor (D09916) 💬

[1] CFTR 💬

[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬

[1] 299 💬