Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Elexacaftor / Ivacaftor / Tezacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
2Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
3Elexacaftor, Tezacaftor, Ivacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
4Elexacaftor-tezacaftor-ivacaftor exposure
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
5Elexacaftor-tezacaftor-ivacaftor treatment
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
6Elexacaftor/tezacaftor/ivacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
7Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(D11041)		[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] Ivacaftor ,
Tezacaftor (D11041),
Elexacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
8TEZACAFTOR
(D11041)		[1] Tezacaftor[1] Tezacaftor (D11041) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
9Tezacaftor (TEZ)
(D11041)		[1] Tezacaftor[1] Tezacaftor (D11041) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
10Tezacaftor/Ivacaftor
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
11Tezacaftor/Ivacaftor + Ivacaftor
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
12Tezacaftor/Ivacaftor 100mg/150mg
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
13Tezacaftor/Ivacaftor/100mg/150mg
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
14Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor, Vanzacaftor-Tezacaftor-Deutivacaftor
(D11041)		[6] Deutivacaftor,
Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor,
Vanzacaftor		[7] Ivacaftor ,
Lumacaftor ,
Tezacaftor (D11041),
Deutivacaftor ,
Elexacaftor ,
Vanzacaftor ,
Vanzacaftor calcium 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
15VX-121/tezacaftor/deutivacaftor
(D11041)		[2] Deutivacaftor,
Tezacaftor		[2] Tezacaftor (D11041),
Deutivacaftor 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
16VX-121/tezacaftor/deutivacaftorProduct Code: VX-121/TEZ/D-IVAPharmaceutical Form: Film-coated tabletINN or Proposed INN: VX-121CAS Number: 2374124-50-0Current Sponsor code: VX-121Other descriptive name: VX-121Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 10-INN or Proposed INN: tezacaftorCAS Number: 1152311-62-0Current Sponsor code: VX-661Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 50-INN or Proposed INN: deutivacaftorCAS Number: 1413431-07-8Current Sponsor code: VX-561Other descriptive name: D-IVAConcentration unit: mg milligram(s)Concentration type: equalConcentration number: 125-Product Name: VX-121/tezacaftor/deutivacaftorProduct Code: VX-121/TEZ/D-IVAPharmaceutical Form: Film-coated tabletINN or Proposed INN: VX-121CAS Number: 2374124-50-0Current Sponsor code: VX-121Other descriptive name: VX-121Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 4-INN or Proposed INN: tezacaftorCAS Number: 1152311-62-0Current Sponsor code: VX-661Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 20-INN or Proposed INN: deutivacaftorCAS Number: 1413431-07-8Current Sponsor code: VX-561Other descriptive name: D-IVAConcentration unit: mg milligram(s)Concentration type: equalConcentration number: 50-Product Name: VX-121/tezacaftor/deutivacaftorProduct Code: VX-121/TEZ/D-IVAPharmaceutical Form: Film-coated tabletINN or Proposed INN: VX-121CAS Number: 2374124-50-0Current Sponsor code: VX-121Other descriptive name: VX-121Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 4-INN or Proposed INN: tezacaftorCAS Number: 1152311-62-0Current Sponsor code: VX-
(D11041)		[1] Tezacaftor[1] Tezacaftor (D11041) 💬 [1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
17VX-659/Tezacaftor/Ivacaftor
(D11041)		[2] Ivacaftor,
Tezacaftor		[2] Ivacaftor ,
Tezacaftor (D11041) 💬 		[1] CFTR 💬 [9] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Phagocytosis, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬