225. 先天性腎性尿崩症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 17 / 薬物数 : 40 - (DrugBank : 19) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 67
薬物、開発者(Primary Sponsor)、臨床試験情報(症例登録開始年(Enrollment year)、フェーズ、ID、実施国)
Acetazolamide sandoz 250
Radboud University Nijmegen Medical Centre
2012 - EUCTR2011-005970-41-NL Netherlands
Adempas
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
Amiloride
Assistance Publique – Hôpitaux de Paris (AP-HP)
2022 Phase 2 EUCTR2021-003600-41-FR France
Radboud University Nijmegen Medical Centre
2007 Phase 4 EUCTR2006-001202-84-NL Netherlands
Anhydrous amiloride hydrochloride
Assistance Publique - Hôpitaux de Paris
2023 Phase 4 NCT05044611 France
Arginine
Radboud University Medical Center
2022 - NCT05307042 Netherlands
Atorvastatin
Lady Davis Institute
2017 Phase 2 NCT02967653 Canada
Calcitonin
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
Chlorothiazide
National Center for Research Resources (NCRR)
1995 - NCT00004360 -
Confortid
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Ddavp
Radboud University Medical Center
2022 - NCT05307042 Netherlands
Desmopressin acetate trihydrate
Radboud University Nijmegen Medical Centre
2013 - EUCTR2012-001809-24-NL Netherlands
Desmopressine nasal spray 10 MG/ML, flacon 60 doses
Radboud University Nijmegen Medical Centre
2013 - EUCTR2012-001809-24-NL Netherlands
Esidrix
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Fluconazole
Claus Bistrup
2020 Phase 2 EUCTR2020-002204-38-DK Denmark
Hydrochloorthiazide
Radboud University Nijmegen Medical Centre
2007 Phase 4 EUCTR2006-001202-84-NL Netherlands
Hydrochlorothiazide
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Hydrochlorothiazide/amiloride
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
Indometacin
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Indomethacin
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
IRM
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Losec
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Measure OF arginine-stimulated copeptin
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Measure OF basal copeptin level
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Metformin
Emory University
2015 Phase 1 NCT02460354 United States
Miacalcic
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Midamor
Radboud University Nijmegen Medical Centre
2007 Phase 4 EUCTR2006-001202-84-NL Netherlands
Modamide 5 MG
Assistance Publique – Hôpitaux de Paris (AP-HP)
2022 Phase 2 EUCTR2021-003600-41-FR France
Omeprazole magnesium
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Riociguat
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
Salmon
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Sevoflurane
Universitair Ziekenhuis Brussel
2021 - NCT04939753 Belgium
Sildenafil
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
Sildenafil citrate
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Spirix
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Spironolactone
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
SUB21605
Radboud University Nijmegen Medical Centre
2013 - EUCTR2012-001809-24-NL Netherlands
Tolvaptan
Department of Nephrology and Endocrinology, The University of Tokyo Hospital
2016 - JPRN-UMIN000021708 Japan
Makita Noriko
2018 Phase 1-2 JPRN-jRCTs031180369 -
Vasopressin
Radboud University Medical Center
2022 - NCT05307042 Netherlands
Viagra
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
Water reduction AT home
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Radboud University Nijmegen Medical Centre
2012 - EUCTR2011-005970-41-NL Netherlands
Adempas
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
Amiloride
Assistance Publique – Hôpitaux de Paris (AP-HP)
2022 Phase 2 EUCTR2021-003600-41-FR France
Radboud University Nijmegen Medical Centre
2007 Phase 4 EUCTR2006-001202-84-NL Netherlands
Anhydrous amiloride hydrochloride
Assistance Publique - Hôpitaux de Paris
2023 Phase 4 NCT05044611 France
Arginine
Radboud University Medical Center
2022 - NCT05307042 Netherlands
Atorvastatin
Lady Davis Institute
2017 Phase 2 NCT02967653 Canada
Calcitonin
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
Chlorothiazide
National Center for Research Resources (NCRR)
1995 - NCT00004360 -
Confortid
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Ddavp
Radboud University Medical Center
2022 - NCT05307042 Netherlands
Desmopressin acetate trihydrate
Radboud University Nijmegen Medical Centre
2013 - EUCTR2012-001809-24-NL Netherlands
Desmopressine nasal spray 10 MG/ML, flacon 60 doses
Radboud University Nijmegen Medical Centre
2013 - EUCTR2012-001809-24-NL Netherlands
Esidrix
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Fluconazole
Claus Bistrup
2020 Phase 2 EUCTR2020-002204-38-DK Denmark
Hydrochloorthiazide
Radboud University Nijmegen Medical Centre
2007 Phase 4 EUCTR2006-001202-84-NL Netherlands
Hydrochlorothiazide
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Hydrochlorothiazide/amiloride
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
Indometacin
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Indomethacin
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
IRM
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Losec
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Measure OF arginine-stimulated copeptin
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Measure OF basal copeptin level
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France
Metformin
Emory University
2015 Phase 1 NCT02460354 United States
Miacalcic
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Midamor
Radboud University Nijmegen Medical Centre
2007 Phase 4 EUCTR2006-001202-84-NL Netherlands
Modamide 5 MG
Assistance Publique – Hôpitaux de Paris (AP-HP)
2022 Phase 2 EUCTR2021-003600-41-FR France
Omeprazole magnesium
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Riociguat
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
Salmon
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Sevoflurane
Universitair Ziekenhuis Brussel
2021 - NCT04939753 Belgium
Sildenafil
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
University of Colorado, Denver
2007 - NCT00478335 Denmark;United States
Sildenafil citrate
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Spirix
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Spironolactone
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
SUB21605
Radboud University Nijmegen Medical Centre
2013 - EUCTR2012-001809-24-NL Netherlands
Tolvaptan
Department of Nephrology and Endocrinology, The University of Tokyo Hospital
2016 - JPRN-UMIN000021708 Japan
Makita Noriko
2018 Phase 1-2 JPRN-jRCTs031180369 -
Vasopressin
Radboud University Medical Center
2022 - NCT05307042 Netherlands
Viagra
Dept. of Pediatrics, The Childrens Hospital, Denver
2009 - EUCTR2006-003360-56-DK Denmark
Odense University Hospital
2017 Phase 2 EUCTR2016-001591-30-DK Denmark
Water reduction AT home
Assistance Publique Hopitaux De Marseille
2025 - NCT06604975 France