160. Congenital ichthyosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 42 / Drugs : 71 - (DrugBank : 21) / Drug target genes : 18 - Drug target pathways : 112
Congenital ichthyosis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 160 | Congenital ichthyosis | - |
| 53 | Sjogren syndrome | 11.681 |
| 49 | Systemic lupus erythematosus | 11.271 |
| 97 | Ulcerative colitis | 9.717 |
| 96 | Crohn disease | 9.668 |
| 46 | Malignant rheumatoid arthritis | 9.643 |
| 162 | Pemphigoid | 9.455 |
| 41 | Giant cell arteritis | 9.455 |
| 93 | Primary biliary cholangitis | 9.371 |
| 269 | Pyogenic arthritis | 8.519 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 8.180 |
| 50 | Dermatomyositis | 7.703 |
| 65 | Primary immunodeficiency | 7.245 |
| 51 | Scleroderma | 7.139 |
| 164 | Oculocutaneous albinism | 6.863 |
| 56 | Behcet disease | 6.790 |
| 39 | Toxic epidermal necrolysis | 6.788 |
| 55 | Relapsing polychondritis | 6.519 |
| 40 | Takayasu arteritis | 6.120 |
| 151 | Rasmussen encephalitis | 6.000 |
| 95 | Autoimmune hepatitis | 5.427 |
| 107 | Juvenile idiopathic arthritis | 5.279 |
| 284 | Diamond-Blackfan anemia | 5.172 |
| 222 | Primary nephrotic syndrome | 5.164 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 285 | Fanconi anemia | 4.741 |
| 271 | Ankylosing spondylitis | 4.423 |
| 60 | Aplastic anemia | 4.402 |
| 63 | Idiopathic thrombocytopenic purpura | 4.346 |
| 36 | Epidermolysis bullosa | 4.281 |
| 37 | Generalised pustular psoriasis | 4.219 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 4.148 |
| 20 | Adrenoleukodystrophy | 4.083 |
| 19 | Lysosomal storage disease | 4.071 |
| 299 | Cystic fibrosis | 3.926 |
| 2 | Amyotrophic lateral sclerosis | 3.762 |
| 286 | Hereditary sideroblastic anemia | 3.646 |
| 38 | Stevens-Johnson syndrome | 3.600 |
| 26 | HTLV-1-associated myelopathy | 3.510 |
| 11 | Myasthenia gravis | 3.388 |
| 58 | Hypertrophic cardiomyopathy | 3.346 |
| 90 | Retinitis pigmentosa | 3.333 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 3.333 |
| 84 | Sarcoidosis | 3.087 |
| 227 | Osler disease | 3.043 |
| 85 | Idiopathic interstitial pneumonia | 3.025 |
| 42 | Polyarteritis nodosa | 2.923 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.894 |
| 228 | Bronchiolitis obliterans | 2.727 |
| 66 | IgA nephropathy | 2.686 |
| 158 | Tuberous sclerosis | 2.686 |
| 274 | Osteogenesis Imperfecta | 2.679 |
| 224 | Purpura nephritis | 2.593 |
| 64 | Thrombotic thrombocytopenic purpura | 2.517 |
| 326 | Osteopetrosis | 2.517 |
| 113 | Muscular dystrophy | 2.407 |
| 283 | Acquired pure red cell aplasia | 2.392 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.375 |
| 28 | Systemic amyloidosis | 2.364 |
| 94 | Primary sclerosing cholangitis | 2.339 |
| 6 | Parkinson disease | 2.128 |
| 61 | Autoimmune hemolytic anemia | 2.111 |
| 300 | IgG4-related disease | 1.000 |
| 324 | Methylglutaconic aciduria | 1.000 |