164. Oculocutaneous albinism Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 17 / Drugs : 57 - (DrugBank : 32) / Drug target genes : 32 - Drug target pathways : 139
Oculocutaneous albinism and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 164 | Oculocutaneous albinism | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 20.480 |
| 46 | Malignant rheumatoid arthritis | 16.484 |
| 51 | Scleroderma | 15.747 |
| 284 | Diamond-Blackfan anemia | 15.068 |
| 85 | Idiopathic interstitial pneumonia | 13.428 |
| 60 | Aplastic anemia | 13.160 |
| 65 | Primary immunodeficiency | 12.387 |
| 285 | Fanconi anemia | 12.047 |
| 222 | Primary nephrotic syndrome | 12.029 |
| 283 | Acquired pure red cell aplasia | 10.770 |
| 11 | Myasthenia gravis | 10.541 |
| 96 | Crohn disease | 10.437 |
| 50 | Dermatomyositis | 10.353 |
| 19 | Lysosomal storage disease | 9.494 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 9.412 |
| 41 | Giant cell arteritis | 9.258 |
| 228 | Bronchiolitis obliterans | 9.258 |
| 55 | Relapsing polychondritis | 8.824 |
| 49 | Systemic lupus erythematosus | 8.718 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 8.672 |
| 97 | Ulcerative colitis | 8.477 |
| 20 | Adrenoleukodystrophy | 8.471 |
| 2 | Amyotrophic lateral sclerosis | 8.317 |
| 286 | Hereditary sideroblastic anemia | 8.000 |
| 93 | Primary biliary cholangitis | 7.953 |
| 95 | Autoimmune hepatitis | 7.867 |
| 42 | Polyarteritis nodosa | 7.819 |
| 28 | Systemic amyloidosis | 7.512 |
| 6 | Parkinson disease | 7.286 |
| 84 | Sarcoidosis | 7.171 |
| 58 | Hypertrophic cardiomyopathy | 7.145 |
| 162 | Pemphigoid | 7.059 |
| 107 | Juvenile idiopathic arthritis | 6.978 |
| 53 | Sjogren syndrome | 6.868 |
| 160 | Congenital ichthyosis | 6.863 |
| 40 | Takayasu arteritis | 6.833 |
| 224 | Purpura nephritis | 6.353 |
| 90 | Retinitis pigmentosa | 6.137 |
| 299 | Cystic fibrosis | 6.058 |
| 151 | Rasmussen encephalitis | 6.000 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 5.961 |
| 56 | Behcet disease | 5.833 |
| 34 | Neurofibromatosis | 5.306 |
| 269 | Pyogenic arthritis | 5.145 |
| 38 | Stevens-Johnson syndrome | 5.145 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 39 | Toxic epidermal necrolysis | 4.979 |
| 66 | IgA nephropathy | 4.958 |
| 326 | Osteopetrosis | 4.941 |
| 26 | HTLV-1-associated myelopathy | 4.799 |
| 61 | Autoimmune hemolytic anemia | 4.765 |
| 36 | Epidermolysis bullosa | 4.382 |
| 113 | Muscular dystrophy | 4.138 |
| 331 | Idiopathic multicentric castleman disease | 3.461 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.313 |
| 44 | Wegener granulomatosis | 3.294 |
| 35 | Pemphigus | 3.210 |
| 43 | Microscopic polyangiitis | 3.176 |
| 227 | Osler disease | 3.133 |
| 7 | Corticobasal degeneration | 3.105 |
| 300 | IgG4-related disease | 3.035 |
| 64 | Thrombotic thrombocytopenic purpura | 2.912 |
| 74 | Prolactin secreting pituitary adenoma | 2.912 |
| 4 | Primary lateral sclerosis | 2.619 |
| 94 | Primary sclerosing cholangitis | 2.619 |
| 201 | Angelman syndrome | 2.406 |
| 271 | Ankylosing spondylitis | 2.390 |
| 309 | Progressive myoclonus epilepsy | 2.316 |
| 63 | Idiopathic thrombocytopenic purpura | 2.306 |
| 274 | Osteogenesis Imperfecta | 2.258 |
| 17 | Multiple system atrophy | 2.079 |
| 16 | Crow-Fukase syndrome | 1.906 |
| 158 | Tuberous sclerosis | 1.906 |
| 140 | Dorabe syndrome | 1.676 |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.632 |
| 172 | Hypophosphatasia | 1.373 |
| 86 | Pulmonary arterial hypertension | 1.355 |
| 106 | Cryopyrin-associated periodic syndrome | 1.059 |
| 108 | TNF receptor-associated periodic syndrome | 1.000 |
| 267 | Hyper-IgD syndrome | 1.000 |
| 241 | Hypertyrosinemia type I | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |