172. Hypophosphatasia Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 34 / Drugs : 17 - (DrugBank : 4) / Drug target genes : 3 - Drug target pathways : 6
Hypophosphatasia and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 172 | Hypophosphatasia | - |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.556 |
| 286 | Hereditary sideroblastic anemia | 1.500 |
| 55 | Relapsing polychondritis | 1.444 |
| 43 | Microscopic polyangiitis | 1.429 |
| 326 | Osteopetrosis | 1.417 |
| 283 | Acquired pure red cell aplasia | 1.407 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 1.407 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 1.397 |
| 44 | Wegener granulomatosis | 1.397 |
| 35 | Pemphigus | 1.394 |
| 284 | Diamond-Blackfan anemia | 1.394 |
| 40 | Takayasu arteritis | 1.387 |
| 42 | Polyarteritis nodosa | 1.385 |
| 285 | Fanconi anemia | 1.378 |
| 256 | Muscle glycogenosis | 1.376 |
| 331 | Idiopathic multicentric castleman disease | 1.376 |
| 162 | Pemphigoid | 1.374 |
| 41 | Giant cell arteritis | 1.374 |
| 164 | Oculocutaneous albinism | 1.373 |
| 93 | Primary biliary cholangitis | 1.371 |
| 56 | Behcet disease | 1.370 |
| 271 | Ankylosing spondylitis | 1.366 |
| 60 | Aplastic anemia | 1.365 |
| 11 | Myasthenia gravis | 1.363 |
| 50 | Dermatomyositis | 1.361 |
| 107 | Juvenile idiopathic arthritis | 1.359 |
| 53 | Sjogren syndrome | 1.358 |
| 19 | Lysosomal storage disease | 1.353 |
| 84 | Sarcoidosis | 1.350 |
| 34 | Neurofibromatosis | 1.349 |
| 65 | Primary immunodeficiency | 1.348 |
| 51 | Scleroderma | 1.345 |
| 49 | Systemic lupus erythematosus | 1.345 |
| 97 | Ulcerative colitis | 1.343 |
| 96 | Crohn disease | 1.341 |
| 46 | Malignant rheumatoid arthritis | 1.341 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 1.338 |