226. Interstitial cystitis with Hunners ulcer Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 177 / Drugs : 208 - (DrugBank : 60) / Drug target genes : 87 - Drug target pathways : 148
Interstitial cystitis with Hunners ulcer and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 226 | Interstitial cystitis with Hunners ulcer | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 39.631 |
| 6 | Parkinson disease | 36.228 |
| 96 | Crohn disease | 31.172 |
| 46 | Malignant rheumatoid arthritis | 29.531 |
| 299 | Cystic fibrosis | 27.407 |
| 2 | Amyotrophic lateral sclerosis | 27.220 |
| 97 | Ulcerative colitis | 23.022 |
| 51 | Scleroderma | 17.211 |
| 63 | Idiopathic thrombocytopenic purpura | 15.797 |
| 246 | Methylmalonic acidemia | 15.294 |
| 70 | Spinal stenosis | 14.455 |
| 53 | Sjogren syndrome | 14.427 |
| 107 | Juvenile idiopathic arthritis | 13.671 |
| 236 | Pseudohypoparathyroidism | 13.600 |
| 113 | Muscular dystrophy | 12.946 |
| 86 | Pulmonary arterial hypertension | 12.600 |
| 298 | Hereditary pancreatitis | 10.430 |
| 78 | Hypopituitarism | 10.355 |
| 38 | Stevens-Johnson syndrome | 10.050 |
| 58 | Hypertrophic cardiomyopathy | 9.914 |
| 50 | Dermatomyositis | 8.937 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 8.750 |
| 224 | Purpura nephritis | 8.571 |
| 156 | Rett syndrome | 8.087 |
| 36 | Epidermolysis bullosa | 7.918 |
| 162 | Pemphigoid | 7.703 |
| 11 | Myasthenia gravis | 7.344 |
| 21 | Mitochondrial disease | 7.181 |
| 95 | Autoimmune hepatitis | 7.164 |
| 28 | Systemic amyloidosis | 6.909 |
| 65 | Primary immunodeficiency | 6.874 |
| 42 | Polyarteritis nodosa | 6.750 |
| 49 | Systemic lupus erythematosus | 6.377 |
| 84 | Sarcoidosis | 6.341 |
| 8 | Huntington disease | 6.286 |
| 90 | Retinitis pigmentosa | 6.188 |
| 10 | Charcot-Marie-Tooth disease | 6.091 |
| 193 | Prader-Willi syndrome | 6.065 |
| 19 | Lysosomal storage disease | 6.012 |
| 151 | Rasmussen encephalitis | 6.000 |
| 85 | Idiopathic interstitial pneumonia | 5.939 |
| 26 | HTLV-1-associated myelopathy | 5.329 |
| 227 | Osler disease | 5.231 |
| 271 | Ankylosing spondylitis | 5.104 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 40 | Takayasu arteritis | 4.938 |
| 158 | Tuberous sclerosis | 4.754 |
| 39 | Toxic epidermal necrolysis | 4.733 |
| 5 | Progressive supranuclear palsy | 4.713 |
| 140 | Dorabe syndrome | 4.688 |
| 56 | Behcet disease | 4.674 |
| 144 | Lennox-Gastaut syndrome | 4.638 |
| 284 | Diamond-Blackfan anemia | 4.430 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 4.402 |
| 285 | Fanconi anemia | 4.375 |
| 60 | Aplastic anemia | 4.276 |
| 168 | Ehlers-Danlos syndrome | 4.188 |
| 41 | Giant cell arteritis | 4.119 |
| 283 | Acquired pure red cell aplasia | 4.111 |
| 231 | Alpha-1-antitrypsin deficiency | 3.973 |
| 66 | IgA nephropathy | 3.973 |
| 254 | Porphyria | 3.947 |
| 265 | Lipodystrophy | 3.943 |
| 43 | Microscopic polyangiitis | 3.883 |
| 167 | Marfan syndrome | 3.825 |
| 269 | Pyogenic arthritis | 3.675 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 3.667 |
| 34 | Neurofibromatosis | 3.595 |
| 20 | Adrenoleukodystrophy | 3.545 |
| 222 | Primary nephrotic syndrome | 3.533 |
| 64 | Thrombotic thrombocytopenic purpura | 3.493 |
| 228 | Bronchiolitis obliterans | 3.375 |
| 164 | Oculocutaneous albinism | 3.313 |
| 55 | Relapsing polychondritis | 3.281 |
| 286 | Hereditary sideroblastic anemia | 3.271 |
| 61 | Autoimmune hemolytic anemia | 3.240 |
| 206 | Fragile X syndrome | 3.125 |
| 127 | Frontotemporal lobar degeneration | 3.006 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 98 | Eosinophilic gastro-intestinal disorder | 2.963 |
| 169 | Menkes disease | 2.951 |
| 170 | Occipital horn syndrome | 2.951 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 2.893 |
| 296 | Biliary atresia | 2.812 |
| 300 | IgG4-related disease | 2.737 |
| 1 | Spinal and bulbar muscular atrophy | 2.695 |
| 93 | Primary biliary cholangitis | 2.600 |
| 17 | Multiple system atrophy | 2.407 |
| 215 | Tetralogy of Fallot | 2.375 |
| 160 | Congenital ichthyosis | 2.375 |
| 22 | Moyamoya disease | 2.324 |
| 81 | Congenital adrenal hyperplasia | 2.311 |
| 251 | Urea cycle disorder | 2.285 |
| 256 | Muscle glycogenosis | 2.173 |
| 118 | Myelomeningocele | 2.125 |
| 212 | Tricuspid atresia | 2.125 |
| 44 | Wegener granulomatosis | 2.116 |
| 35 | Pemphigus | 2.045 |
| 274 | Osteogenesis Imperfecta | 2.037 |
| 337 | Homocystinuria | 2.000 |
| 120 | Hereditary dystonia | 2.000 |
| 294 | Congenital diaphragmatic hernia | 1.856 |
| 157 | Sturge-Weber syndrome | 1.856 |
| 278 | Huge lymphatic malformation with cervicofacial lesion | 1.856 |
| 326 | Osteopetrosis | 1.831 |
| 114 | Non-dystrophic myotonia syndrome | 1.671 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.671 |
| 83 | Addison disease | 1.570 |
| 124 | Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy | 1.570 |
| 171 | Wilson disease | 1.354 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 1.132 |
| 94 | Primary sclerosing cholangitis | 1.039 |
| 317 | Trifunctional protein deficiency | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |