234. Peroxisomal disease (except Adrenoleukodystrophy) Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 118 / Drugs : 85 - (DrugBank : 18) / Drug target genes : 15 - Drug target pathways : 50
Peroxisomal disease (except Adrenoleukodystrophy) and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | - |
| 20 | Adrenoleukodystrophy | 10.542 |
| 96 | Crohn disease | 10.143 |
| 46 | Malignant rheumatoid arthritis | 10.138 |
| 60 | Aplastic anemia | 8.730 |
| 19 | Lysosomal storage disease | 8.575 |
| 49 | Systemic lupus erythematosus | 8.480 |
| 326 | Osteopetrosis | 6.667 |
| 283 | Acquired pure red cell aplasia | 6.519 |
| 95 | Autoimmune hepatitis | 6.456 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 6.349 |
| 284 | Diamond-Blackfan anemia | 6.303 |
| 61 | Autoimmune hemolytic anemia | 6.187 |
| 40 | Takayasu arteritis | 6.187 |
| 285 | Fanconi anemia | 6.044 |
| 164 | Oculocutaneous albinism | 5.961 |
| 93 | Primary biliary cholangitis | 5.943 |
| 11 | Myasthenia gravis | 5.807 |
| 36 | Epidermolysis bullosa | 5.769 |
| 28 | Systemic amyloidosis | 5.657 |
| 65 | Primary immunodeficiency | 5.570 |
| 85 | Idiopathic interstitial pneumonia | 5.549 |
| 51 | Scleroderma | 5.522 |
| 224 | Purpura nephritis | 5.444 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 5.414 |
| 286 | Hereditary sideroblastic anemia | 5.250 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 5.218 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 42 | Polyarteritis nodosa | 4.869 |
| 162 | Pemphigoid | 4.702 |
| 228 | Bronchiolitis obliterans | 4.702 |
| 66 | IgA nephropathy | 4.667 |
| 151 | Rasmussen encephalitis | 4.514 |
| 53 | Sjogren syndrome | 4.455 |
| 222 | Primary nephrotic syndrome | 4.418 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.402 |
| 2 | Amyotrophic lateral sclerosis | 4.202 |
| 39 | Toxic epidermal necrolysis | 3.409 |
| 55 | Relapsing polychondritis | 3.299 |
| 299 | Cystic fibrosis | 3.188 |
| 97 | Ulcerative colitis | 3.126 |
| 274 | Osteogenesis Imperfecta | 3.125 |
| 6 | Parkinson disease | 3.096 |
| 38 | Stevens-Johnson syndrome | 3.056 |
| 269 | Pyogenic arthritis | 3.056 |
| 64 | Thrombotic thrombocytopenic purpura | 2.995 |
| 160 | Congenital ichthyosis | 2.894 |
| 227 | Osler disease | 2.717 |
| 41 | Giant cell arteritis | 2.525 |
| 158 | Tuberous sclerosis | 2.500 |
| 56 | Behcet disease | 2.488 |
| 26 | HTLV-1-associated myelopathy | 2.467 |
| 63 | Idiopathic thrombocytopenic purpura | 2.407 |
| 50 | Dermatomyositis | 2.387 |
| 58 | Hypertrophic cardiomyopathy | 2.387 |
| 90 | Retinitis pigmentosa | 2.381 |
| 107 | Juvenile idiopathic arthritis | 2.364 |
| 113 | Muscular dystrophy | 2.331 |
| 94 | Primary sclerosing cholangitis | 1.895 |