271. Ankylosing spondylitis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 631 / Drugs : 405 - (DrugBank : 73) / Drug target genes : 38 - Drug target pathways : 144
Ankylosing spondylitis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 271 | Ankylosing spondylitis | - |
| 46 | Malignant rheumatoid arthritis | 39.235 |
| 97 | Ulcerative colitis | 25.078 |
| 96 | Crohn disease | 21.977 |
| 107 | Juvenile idiopathic arthritis | 21.244 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 18.716 |
| 50 | Dermatomyositis | 17.741 |
| 51 | Scleroderma | 17.402 |
| 49 | Systemic lupus erythematosus | 14.940 |
| 84 | Sarcoidosis | 14.540 |
| 53 | Sjogren syndrome | 13.481 |
| 162 | Pemphigoid | 13.410 |
| 41 | Giant cell arteritis | 12.175 |
| 65 | Primary immunodeficiency | 12.033 |
| 56 | Behcet disease | 10.580 |
| 40 | Takayasu arteritis | 9.943 |
| 6 | Parkinson disease | 8.869 |
| 11 | Myasthenia gravis | 8.659 |
| 93 | Primary biliary cholangitis | 8.468 |
| 44 | Wegener granulomatosis | 8.362 |
| 299 | Cystic fibrosis | 6.974 |
| 270 | Chronic recurrent multifocal osteomyelitis | 6.000 |
| 298 | Hereditary pancreatitis | 5.434 |
| 222 | Primary nephrotic syndrome | 5.182 |
| 226 | Interstitial cystitis with Hunners ulcer | 5.104 |
| 60 | Aplastic anemia | 5.059 |
| 300 | IgG4-related disease | 4.995 |
| 269 | Pyogenic arthritis | 4.995 |
| 256 | Muscle glycogenosis | 4.878 |
| 55 | Relapsing polychondritis | 4.581 |
| 160 | Congenital ichthyosis | 4.423 |
| 2 | Amyotrophic lateral sclerosis | 4.104 |
| 43 | Microscopic polyangiitis | 4.098 |
| 35 | Pemphigus | 3.902 |
| 19 | Lysosomal storage disease | 3.535 |
| 78 | Hypopituitarism | 3.412 |
| 63 | Idiopathic thrombocytopenic purpura | 3.380 |
| 95 | Autoimmune hepatitis | 3.334 |
| 285 | Fanconi anemia | 3.278 |
| 86 | Pulmonary arterial hypertension | 3.195 |
| 284 | Diamond-Blackfan anemia | 3.042 |
| 66 | IgA nephropathy | 3.033 |
| 265 | Lipodystrophy | 2.758 |
| 42 | Polyarteritis nodosa | 2.758 |
| 8 | Huntington disease | 2.728 |
| 21 | Mitochondrial disease | 2.657 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 2.585 |
| 113 | Muscular dystrophy | 2.434 |
| 37 | Generalised pustular psoriasis | 2.415 |
| 164 | Oculocutaneous albinism | 2.390 |
| 70 | Spinal stenosis | 2.341 |
| 251 | Urea cycle disorder | 2.305 |
| 85 | Idiopathic interstitial pneumonia | 2.081 |
| 224 | Purpura nephritis | 2.073 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 337 | Homocystinuria | 2.000 |
| 257 | Hepatic glycogenosis | 2.000 |
| 282 | Congenital dyserythropoietic anemia | 2.000 |
| 331 | Idiopathic multicentric castleman disease | 1.869 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.829 |
| 228 | Bronchiolitis obliterans | 1.809 |
| 158 | Tuberous sclerosis | 1.756 |
| 34 | Neurofibromatosis | 1.662 |
| 218 | Alport syndrome | 1.610 |
| 36 | Epidermolysis bullosa | 1.505 |
| 206 | Fragile X syndrome | 1.447 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 1.422 |
| 310 | Congenital anomalies syndrome | 1.366 |
| 172 | Hypophosphatasia | 1.366 |
| 225 | Congenital nephrogenic diabetes insipidus | 1.341 |
| 246 | Methylmalonic acidemia | 1.240 |
| 283 | Acquired pure red cell aplasia | 1.192 |
| 94 | Primary sclerosing cholangitis | 1.150 |
| 79 | Homozygous familial hypercholesterolemia | 1.146 |
| 98 | Eosinophilic gastro-intestinal disorder | 1.145 |
| 236 | Pseudohypoparathyroidism | 1.112 |
| 58 | Hypertrophic cardiomyopathy | 1.067 |
| 333 | Hutchinson-Gilford syndrome | 1.049 |
| 235 | Hypoparathyroidism | 1.049 |
| 71 | Idiopathic osteonecrosis of the femoral head | 1.049 |
| 317 | Trifunctional protein deficiency | 1.000 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |