300. IgG4-related disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 81 / Drugs : 90 - (DrugBank : 31) / Drug target genes : 23 - Drug target pathways : 152
IgG4-related disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 300 | IgG4-related disease | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 15.000 |
| 46 | Malignant rheumatoid arthritis | 13.137 |
| 49 | Systemic lupus erythematosus | 11.464 |
| 11 | Myasthenia gravis | 10.240 |
| 51 | Scleroderma | 9.855 |
| 222 | Primary nephrotic syndrome | 8.596 |
| 53 | Sjogren syndrome | 7.273 |
| 65 | Primary immunodeficiency | 7.037 |
| 96 | Crohn disease | 6.865 |
| 35 | Pemphigus | 5.624 |
| 271 | Ankylosing spondylitis | 4.995 |
| 60 | Aplastic anemia | 4.978 |
| 107 | Juvenile idiopathic arthritis | 4.841 |
| 44 | Wegener granulomatosis | 4.511 |
| 284 | Diamond-Blackfan anemia | 4.455 |
| 61 | Autoimmune hemolytic anemia | 4.312 |
| 285 | Fanconi anemia | 4.138 |
| 43 | Microscopic polyangiitis | 3.943 |
| 28 | Systemic amyloidosis | 3.663 |
| 19 | Lysosomal storage disease | 3.645 |
| 84 | Sarcoidosis | 3.585 |
| 95 | Autoimmune hepatitis | 3.537 |
| 97 | Ulcerative colitis | 3.449 |
| 2 | Amyotrophic lateral sclerosis | 3.419 |
| 162 | Pemphigoid | 3.055 |
| 164 | Oculocutaneous albinism | 3.035 |
| 66 | IgA nephropathy | 3.017 |
| 93 | Primary biliary cholangitis | 3.017 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.737 |
| 86 | Pulmonary arterial hypertension | 2.616 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 2.593 |
| 94 | Primary sclerosing cholangitis | 2.544 |
| 6 | Parkinson disease | 2.515 |
| 251 | Urea cycle disorder | 2.400 |
| 42 | Polyarteritis nodosa | 2.308 |
| 41 | Giant cell arteritis | 2.172 |
| 55 | Relapsing polychondritis | 2.044 |
| 50 | Dermatomyositis | 2.014 |
| 337 | Homocystinuria | 2.000 |
| 224 | Purpura nephritis | 1.849 |
| 85 | Idiopathic interstitial pneumonia | 1.835 |
| 283 | Acquired pure red cell aplasia | 1.719 |
| 256 | Muscle glycogenosis | 1.445 |
| 331 | Idiopathic multicentric castleman disease | 1.445 |
| 228 | Bronchiolitis obliterans | 1.422 |
| 98 | Eosinophilic gastro-intestinal disorder | 1.353 |
| 296 | Biliary atresia | 1.327 |
| 298 | Hereditary pancreatitis | 1.288 |
| 70 | Spinal stenosis | 1.244 |
| 14 | Chronic inflammatory demyelinating polyneuropathy | 1.200 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |
| 160 | Congenital ichthyosis | 1.000 |