326. Osteopetrosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 18 / Drugs : 43 - (DrugBank : 14) / Drug target genes : 17 - Drug target pathways : 82
Osteopetrosis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 326 | Osteopetrosis | - |
| 65 | Primary immunodeficiency | 12.522 |
| 60 | Aplastic anemia | 9.857 |
| 19 | Lysosomal storage disease | 9.522 |
| 46 | Malignant rheumatoid arthritis | 9.195 |
| 286 | Hereditary sideroblastic anemia | 8.000 |
| 49 | Systemic lupus erythematosus | 7.894 |
| 96 | Crohn disease | 7.788 |
| 40 | Takayasu arteritis | 7.750 |
| 20 | Adrenoleukodystrophy | 6.673 |
| 284 | Diamond-Blackfan anemia | 6.673 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 6.667 |
| 285 | Fanconi anemia | 6.244 |
| 283 | Acquired pure red cell aplasia | 5.778 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 5.524 |
| 85 | Idiopathic interstitial pneumonia | 5.420 |
| 51 | Scleroderma | 5.376 |
| 55 | Relapsing polychondritis | 5.359 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 5.196 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 162 | Pemphigoid | 4.970 |
| 228 | Bronchiolitis obliterans | 4.970 |
| 41 | Giant cell arteritis | 4.970 |
| 164 | Oculocutaneous albinism | 4.941 |
| 56 | Behcet disease | 4.889 |
| 11 | Myasthenia gravis | 4.711 |
| 50 | Dermatomyositis | 4.667 |
| 107 | Juvenile idiopathic arthritis | 4.615 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 4.594 |
| 53 | Sjogren syndrome | 4.582 |
| 151 | Rasmussen encephalitis | 4.427 |
| 299 | Cystic fibrosis | 4.333 |
| 97 | Ulcerative colitis | 4.224 |
| 42 | Polyarteritis nodosa | 4.123 |
| 274 | Osteogenesis Imperfecta | 3.857 |
| 93 | Primary biliary cholangitis | 3.850 |
| 36 | Epidermolysis bullosa | 3.625 |
| 28 | Systemic amyloidosis | 3.480 |
| 61 | Autoimmune hemolytic anemia | 3.150 |
| 39 | Toxic epidermal necrolysis | 3.125 |
| 66 | IgA nephropathy | 2.893 |
| 158 | Tuberous sclerosis | 2.893 |
| 38 | Stevens-Johnson syndrome | 2.708 |
| 269 | Pyogenic arthritis | 2.708 |
| 224 | Purpura nephritis | 2.708 |
| 64 | Thrombotic thrombocytopenic purpura | 2.637 |
| 113 | Muscular dystrophy | 2.631 |
| 160 | Congenital ichthyosis | 2.517 |
| 95 | Autoimmune hepatitis | 2.467 |
| 235 | Hypoparathyroidism | 2.391 |
| 6 | Parkinson disease | 2.370 |
| 227 | Osler disease | 2.310 |
| 26 | HTLV-1-associated myelopathy | 2.015 |
| 63 | Idiopathic thrombocytopenic purpura | 1.944 |
| 58 | Hypertrophic cardiomyopathy | 1.921 |
| 90 | Retinitis pigmentosa | 1.913 |
| 222 | Primary nephrotic syndrome | 1.844 |
| 226 | Interstitial cystitis with Hunners ulcer | 1.831 |
| 2 | Amyotrophic lateral sclerosis | 1.662 |
| 172 | Hypophosphatasia | 1.417 |
| 68 | Ossification of the ligamentum flavum | 1.000 |