DR info

Clinical trials : 33 / Drugs : 41 - (DrugBank : 21) / Drug target genes : 22 - Drug target pathways : 123

Idiopathic multicentric castleman disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
331	Idiopathic multicentric castleman disease	-
34	Neurofibromatosis	23.060
65	Primary immunodeficiency	21.505
85	Idiopathic interstitial pneumonia	21.383
26	HTLV-1-associated myelopathy	19.311
2	Amyotrophic lateral sclerosis	15.053
13	Multiple sclerosis/Neuromyelitis optica	14.761
51	Scleroderma	14.159
46	Malignant rheumatoid arthritis	13.670
42	Polyarteritis nodosa	13.022
49	Systemic lupus erythematosus	12.871
28	Systemic amyloidosis	11.300
56	Behcet disease	10.484
256	Muscle glycogenosis	8.617
93	Primary biliary cholangitis	8.255
266	Familial mediterranean fever	8.065
102	Rubinstein-Taybi syndrome	7.000
222	Primary nephrotic syndrome	6.092
89	Lymphangioleiomyomatosis	5.735
233	Wolfram syndrome	5.029
127	Frontotemporal lobar degeneration	4.919
60	Aplastic anemia	4.839
210	Single Ventricle	4.409
6	Parkinson disease	4.318
11	Myasthenia gravis	3.890
90	Retinitis pigmentosa	3.786
283	Acquired pure red cell aplasia	3.688
41	Giant cell arteritis	3.503
164	Oculocutaneous albinism	3.461
35	Pemphigus	3.305
16	Crow-Fukase syndrome	3.303
43	Microscopic polyangiitis	3.235
86	Pulmonary arterial hypertension	3.188
3	Spinal muscular atrophy	2.960
285	Fanconi anemia	2.845
45	Eosinophilic granulomatosis with Polyangiitis	2.774
84	Sarcoidosis	2.644
55	Relapsing polychondritis	2.554
284	Diamond-Blackfan anemia	2.481
50	Dermatomyositis	2.371
40	Takayasu arteritis	2.323
53	Sjogren syndrome	2.270
5	Progressive supranuclear palsy	2.164
19	Lysosomal storage disease	2.130
271	Ankylosing spondylitis	1.869
96	Crohn disease	1.806
44	Wegener granulomatosis	1.805
62	Paroxysmal nocturnal hemoglobinuria	1.805
14	Chronic inflammatory demyelinating polyneuropathy	1.677
270	Chronic recurrent multifocal osteomyelitis	1.645
61	Autoimmune hemolytic anemia	1.645
300	IgG4-related disease	1.445
162	Pemphigoid	1.442
228	Bronchiolitis obliterans	1.442
172	Hypophosphatasia	1.376
63	Idiopathic thrombocytopenic purpura	1.272
94	Primary sclerosing cholangitis	1.250
58	Hypertrophic cardiomyopathy	1.243
107	Juvenile idiopathic arthritis	1.210
54	Adult still disease	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000