331. Idiopathic multicentric castleman disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 40 / Drugs : 45 - (DrugBank : 29) / Drug target genes : 43 - Drug target pathways : 163
Idiopathic multicentric castleman disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 331 | Idiopathic multicentric castleman disease | - |
| 34 | Neurofibromatosis | 23.060 |
| 65 | Primary immunodeficiency | 21.505 |
| 85 | Idiopathic interstitial pneumonia | 21.383 |
| 26 | HTLV-1-associated myelopathy | 19.311 |
| 2 | Amyotrophic lateral sclerosis | 15.053 |
| 13 | Multiple sclerosis | 14.761 |
| 51 | Scleroderma | 14.159 |
| 46 | Malignant rheumatoid arthritis | 13.670 |
| 42 | Polyarteritis nodosa | 13.022 |
| 49 | Systemic lupus erythematosus | 12.871 |
| 28 | Systemic amyloidosis | 11.300 |
| 56 | Behcet disease | 10.484 |
| 256 | Muscle glycogenosis | 8.617 |
| 93 | Primary biliary cholangitis | 8.255 |
| 266 | Familial mediterranean fever | 8.065 |
| 102 | Rubinstein-Taybi syndrome | 7.000 |
| 222 | Primary nephrotic syndrome | 6.092 |
| 89 | Lymphangioleiomyomatosis | 5.735 |
| 233 | Wolfram syndrome | 5.029 |
| 127 | Frontotemporal lobar degeneration | 4.919 |
| 60 | Aplastic anemia | 4.839 |
| 210 | Single Ventricle | 4.409 |
| 6 | Parkinson disease | 4.318 |
| 11 | Myasthenia gravis | 3.890 |
| 90 | Retinitis pigmentosa | 3.786 |
| 283 | Acquired pure red cell aplasia | 3.688 |
| 41 | Giant cell arteritis | 3.503 |
| 164 | Oculocutaneous albinism | 3.461 |
| 35 | Pemphigus | 3.305 |
| 16 | Crow-Fukase syndrome | 3.303 |
| 43 | Microscopic polyangiitis | 3.235 |
| 86 | Pulmonary arterial hypertension | 3.188 |
| 3 | Spinal muscular atrophy | 2.960 |
| 285 | Fanconi anemia | 2.845 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 2.774 |
| 84 | Sarcoidosis | 2.644 |
| 55 | Relapsing polychondritis | 2.554 |
| 284 | Diamond-Blackfan anemia | 2.481 |
| 50 | Dermatomyositis | 2.371 |
| 40 | Takayasu arteritis | 2.323 |
| 53 | Sjogren syndrome | 2.270 |
| 5 | Progressive supranuclear palsy | 2.164 |
| 19 | Lysosomal storage disease | 2.130 |
| 271 | Ankylosing spondylitis | 1.869 |
| 96 | Crohn disease | 1.806 |
| 44 | Wegener granulomatosis | 1.805 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 1.805 |
| 14 | Chronic inflammatory demyelinating polyneuropathy | 1.677 |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.645 |
| 61 | Autoimmune hemolytic anemia | 1.645 |
| 300 | IgG4-related disease | 1.445 |
| 162 | Pemphigoid | 1.442 |
| 228 | Bronchiolitis obliterans | 1.442 |
| 172 | Hypophosphatasia | 1.376 |
| 63 | Idiopathic thrombocytopenic purpura | 1.272 |
| 94 | Primary sclerosing cholangitis | 1.250 |
| 58 | Hypertrophic cardiomyopathy | 1.243 |
| 107 | Juvenile idiopathic arthritis | 1.210 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |