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DR info

Clinical trials : 23 / Drugs : 31 - (DrugBank : 11) / Drug target genes : 3 - Drug target pathways : 26

Drugs, Primary sponsors and Trial info (Enrollment year, Phase, Trial ID, Countries)

5-mthf
   Zambon Group S.p.A
      2007   -   EUCTR2006-000614-21-AT   Austria;Hungary;Italy;United Kingdom
      2006   Phase 2   EUCTR2006-000614-21-SK   Austria;Hungary;Slovakia;United Kingdom
      2006   Phase 2   EUCTR2006-000614-21-HU   Austria;Hungary;Slovakia;United Kingdom
      2006   -   EUCTR2006-000614-21-GB   Austria;Hungary;Italy;United Kingdom
Acetaminophen
   Hospital de Clinicas de Porto Alegre
      2022   Phase 1/Phase 2   NCT04015557   Brazil
ACN00177
   Aeglea Biotherapeutics, Inc.
      2020   Phase 1   EUCTR2019-004791-19-GB   United Kingdom
Betaine
   Assistance Publique - Hôpitaux de Paris
      2015   Phase 2   NCT02404337   France
Creatine
   University of British Columbia
      2024   -   NCT06495567   Canada
Cysteine
   Hamad Medical Corporation
      2024   -   NCT06622577   Qatar
Detoxifying agents FOR antineoplastic treatment
   ZAMBON GROUP
      2006   -   EUCTR2006-000614-21-IT   Austria;Hungary;Italy;United Kingdom
Dietary methionine tracer and protein intake
   University of British Columbia
      2024   -   NCT06495567   Canada
EPI-743
   Bambino Gesù Hospital and Research Institute
      2013   Phase 2   NCT01793090   Italy
Hydroxocobalamin chloride injection
   CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
      2025   Phase 3   NCT07163364   -
Iupac name: 2-[4-[(2-amino-5-methyl-4-OXO-1,6,7,8-tetrahydropteridin-6-YL)methylam INO]benzoyl]amino
   Zambon Group S.p.A
      2007   -   EUCTR2006-000614-21-AT   Austria;Hungary;Italy;United Kingdom
      2006   Phase 2   EUCTR2006-000614-21-SK   Austria;Hungary;Slovakia;United Kingdom
      2006   Phase 2   EUCTR2006-000614-21-HU   Austria;Hungary;Slovakia;United Kingdom
      2006   -   EUCTR2006-000614-21-GB   Austria;Hungary;Italy;United Kingdom
Methylenetetrahydrofolate reductase (mthfr) deficiency
   Istanbul Medeniyet University
      2019   -   NCT04287881   Turkey
N-acetylcysteine
   Hospital de Clinicas de Porto Alegre
      2022   Phase 1/Phase 2   NCT04015557   Brazil
   McGill University Health Center
      2007   Phase 2   NCT00483314   Canada
Obtaining DRY blood spots from healthy children aged 8 days - 7 years
   West Kazakhstan Medical University
      2022   -   NCT05910151   Kazakhstan
Obtaining DRY blood spots from healthy children aged 8-18 years
   West Kazakhstan Medical University
      2022   -   NCT05910151   Kazakhstan
Pegtarviliase IV
   Aeglea Biotherapeutics
      2021   Phase 1/Phase 2   NCT05154890   Australia;United Kingdom;United States
Pegtarviliase SC
   Aeglea Biotherapeutics
      2021   Phase 1/Phase 2   NCT05154890   Australia;United Kingdom;United States
Pegtibatinase
   Travere Therapeutics, Inc.
      2024   Phase 3   NCT06431893   Australia;Belgium;France;Germany;Ireland;Italy;Poland;Portugal;Qatar;Saudi Arabia;Spain;Turkey (Türkiye);United Kingdom;United States
      2023   Phase 3   NCT06247085   Australia;Belgium;France;Germany;Ireland;Italy;Poland;Portugal;Qatar;Saudi Arabia;Spain;Turkey (Türkiye);United Kingdom;United States
      2019   Phase 1/Phase 2   NCT03406611   United States
PKU express plus
   Vitaflo International, Ltd
      2021   -   NCT05051657   United Kingdom
Prefolic
   Zambon Group S.p.A
      2007   -   EUCTR2006-000614-21-AT   Austria;Hungary;Italy;United Kingdom
      2006   Phase 2   EUCTR2006-000614-21-SK   Austria;Hungary;Slovakia;United Kingdom
      2006   Phase 2   EUCTR2006-000614-21-HU   Austria;Hungary;Slovakia;United Kingdom
      2006   -   EUCTR2006-000614-21-GB   Austria;Hungary;Italy;United Kingdom
Prefolic 15*30CPR gastror 15MG
   ZAMBON GROUP
      2006   -   EUCTR2006-000614-21-IT   Austria;Hungary;Italy;United Kingdom
SYNB1353
   Synlogic
      2022   Phase 1   NCT05462132   United States
Taurine
   University of Colorado, Denver
      2010   Phase 1/Phase 2   NCT01192828   United States