DR info

Clinical trials : 163 / Drugs : 185 - (DrugBank : 46) / Drug target genes : 50 - Drug target pathways : 125

Epidermolysis bullosa and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
36	Epidermolysis bullosa	-
13	Multiple sclerosis/Neuromyelitis optica	41.948
46	Malignant rheumatoid arthritis	38.959
96	Crohn disease	31.399
6	Parkinson disease	31.194
2	Amyotrophic lateral sclerosis	27.035
97	Ulcerative colitis	24.711
298	Hereditary pancreatitis	23.640
158	Tuberous sclerosis	21.501
231	Alpha-1-antitrypsin deficiency	20.152
70	Spinal stenosis	19.837
84	Sarcoidosis	17.666
193	Prader-Willi syndrome	17.517
140	Dorabe syndrome	16.644
144	Lennox-Gastaut syndrome	16.524
152	PCDH19 related syndrome	16.000
34	Neurofibromatosis	15.133
156	Rett syndrome	14.441
145	West syndrome	14.204
8	Huntington disease	14.138
201	Angelman syndrome	13.061
98	Eosinophilic gastrointestinal disease	12.758
205	Fragile X syndrome related disease	12.121
17	Multiple system atrophy	12.044
75	Cushing disease	11.982
272	Fibrodysplasia ossificans progressiva	11.856
22	Moyamoya disease	11.382
51	Scleroderma	11.230
155	Acquired aphasia with convulsive disorder	11.170
296	Biliary atresia	11.167
18	Spinocerebellar degeneration	11.167
206	Fragile X syndrome	10.408
38	Stevens-Johnson syndrome	10.188
53	Sjogren syndrome	9.329
21	Mitochondrial disease	8.893
5	Progressive supranuclear palsy	8.802
19	Lysosomal storage disease	8.633
3	Spinal muscular atrophy	8.477
62	Paroxysmal nocturnal hemoglobinuria	8.117
226	Interstitial cystitis with Hunners ulcer	7.918
283	Acquired pure red cell aplasia	7.683
85	Idiopathic interstitial pneumonia	6.966
28	Systemic amyloidosis	6.957
45	Eosinophilic granulomatosis with Polyangiitis	6.463
113	Muscular dystrophy	6.373
39	Toxic epidermal necrolysis	6.174
49	Systemic lupus erythematosus	5.961
234	Peroxisomal disease (except Adrenoleukodystrophy)	5.769
284	Diamond-Blackfan anemia	5.659
285	Fanconi anemia	5.597
60	Aplastic anemia	5.528
61	Autoimmune hemolytic anemia	5.224
66	IgA nephropathy	5.150
95	Autoimmune hepatitis	5.133
42	Polyarteritis nodosa	5.102
107	Juvenile idiopathic arthritis	5.030
302	Leber hereditary optic neuropathy	5.000
224	Purpura nephritis	4.876
65	Primary immunodeficiency	4.829
286	Hereditary sideroblastic anemia	4.684
20	Adrenoleukodystrophy	4.659
162	Pemphigoid	4.453
228	Bronchiolitis obliterans	4.453
41	Giant cell arteritis	4.453
58	Hypertrophic cardiomyopathy	4.424
164	Oculocutaneous albinism	4.382
160	Congenital ichthyosis	4.281
151	Rasmussen encephalitis	4.252
168	Ehlers-Danlos syndrome	4.245
11	Myasthenia gravis	3.810
326	Osteopetrosis	3.625
10	Charcot-Marie-Tooth disease	3.607
40	Takayasu arteritis	3.448
55	Relapsing polychondritis	3.367
222	Primary nephrotic syndrome	3.346
63	Idiopathic thrombocytopenic purpura	3.122
256	Muscle glycogenosis	3.034
274	Osteogenesis Imperfecta	2.991
299	Cystic fibrosis	2.870
269	Pyogenic arthritis	2.841
86	Pulmonary arterial hypertension	2.837
93	Primary biliary cholangitis	2.836
1	Spinal and bulbar muscular atrophy	2.755
64	Thrombotic thrombocytopenic purpura	2.709
50	Dermatomyositis	2.422
94	Primary sclerosing cholangitis	2.397
56	Behcet disease	2.167
227	Osler disease	2.108
26	HTLV-1-associated myelopathy	2.105
127	Frontotemporal lobar degeneration	2.050
157	Sturge-Weber syndrome	1.873
90	Retinitis pigmentosa	1.857
114	Non-dystrophic myotonia syndrome	1.757
35	Pemphigus	1.531
271	Ankylosing spondylitis	1.505
43	Microscopic polyangiitis	1.376
37	Generalised pustular psoriasis	1.061
44	Wegener granulomatosis	1.026
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000
52	Mixed connective tissue disease	1.000