38. Stevens-Johnson syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 20 / Drugs : 29 - (DrugBank : 10) / Drug target genes : 15 - Drug target pathways : 100
Stevens-Johnson syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 38 | Stevens-Johnson syndrome | - |
| 28 | Systemic amyloidosis | 13.265 |
| 51 | Scleroderma | 13.182 |
| 46 | Malignant rheumatoid arthritis | 13.137 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 13.116 |
| 107 | Juvenile idiopathic arthritis | 11.700 |
| 53 | Sjogren syndrome | 11.676 |
| 96 | Crohn disease | 11.401 |
| 2 | Amyotrophic lateral sclerosis | 11.398 |
| 36 | Epidermolysis bullosa | 10.188 |
| 113 | Muscular dystrophy | 10.088 |
| 226 | Interstitial cystitis with Hunners ulcer | 10.050 |
| 97 | Ulcerative colitis | 9.801 |
| 6 | Parkinson disease | 9.753 |
| 58 | Hypertrophic cardiomyopathy | 8.739 |
| 39 | Toxic epidermal necrolysis | 8.345 |
| 85 | Idiopathic interstitial pneumonia | 7.003 |
| 285 | Fanconi anemia | 6.480 |
| 228 | Bronchiolitis obliterans | 6.382 |
| 60 | Aplastic anemia | 6.171 |
| 151 | Rasmussen encephalitis | 6.000 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 5.926 |
| 65 | Primary immunodeficiency | 5.760 |
| 284 | Diamond-Blackfan anemia | 5.624 |
| 40 | Takayasu arteritis | 5.461 |
| 42 | Polyarteritis nodosa | 5.415 |
| 41 | Giant cell arteritis | 5.172 |
| 164 | Oculocutaneous albinism | 5.145 |
| 56 | Behcet disease | 5.096 |
| 26 | HTLV-1-associated myelopathy | 5.053 |
| 269 | Pyogenic arthritis | 5.009 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 50 | Dermatomyositis | 4.889 |
| 298 | Hereditary pancreatitis | 4.830 |
| 283 | Acquired pure red cell aplasia | 4.719 |
| 19 | Lysosomal storage disease | 4.700 |
| 95 | Autoimmune hepatitis | 4.642 |
| 49 | Systemic lupus erythematosus | 4.529 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 4.511 |
| 227 | Osler disease | 4.403 |
| 55 | Relapsing polychondritis | 4.200 |
| 162 | Pemphigoid | 4.059 |
| 11 | Myasthenia gravis | 3.847 |
| 224 | Purpura nephritis | 3.840 |
| 286 | Hereditary sideroblastic anemia | 3.750 |
| 64 | Thrombotic thrombocytopenic purpura | 3.750 |
| 222 | Primary nephrotic syndrome | 3.695 |
| 160 | Congenital ichthyosis | 3.600 |
| 84 | Sarcoidosis | 3.585 |
| 34 | Neurofibromatosis | 3.567 |
| 168 | Ehlers-Danlos syndrome | 3.519 |
| 20 | Adrenoleukodystrophy | 3.382 |
| 1 | Spinal and bulbar muscular atrophy | 3.333 |
| 61 | Autoimmune hemolytic anemia | 3.264 |
| 10 | Charcot-Marie-Tooth disease | 3.182 |
| 256 | Muscle glycogenosis | 3.097 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 3.056 |
| 66 | IgA nephropathy | 3.017 |
| 93 | Primary biliary cholangitis | 3.017 |
| 127 | Frontotemporal lobar degeneration | 2.940 |
| 63 | Idiopathic thrombocytopenic purpura | 2.880 |
| 274 | Osteogenesis Imperfecta | 2.857 |
| 90 | Retinitis pigmentosa | 2.841 |
| 70 | Spinal stenosis | 2.727 |
| 326 | Osteopetrosis | 2.708 |
| 299 | Cystic fibrosis | 2.625 |
| 86 | Pulmonary arterial hypertension | 2.616 |
| 114 | Non-dystrophic myotonia syndrome | 2.593 |
| 231 | Alpha-1-antitrypsin deficiency | 2.143 |
| 158 | Tuberous sclerosis | 2.143 |
| 16 | Crow-Fukase syndrome | 2.040 |
| 140 | Dorabe syndrome | 2.014 |
| 144 | Lennox-Gastaut syndrome | 2.007 |
| 193 | Prader-Willi syndrome | 1.993 |
| 156 | Rett syndrome | 1.883 |
| 8 | Huntington disease | 1.865 |
| 35 | Pemphigus | 1.600 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |