40. Takayasu arteritis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 24 / Drugs : 40 - (DrugBank : 18) / Drug target genes : 23 - Drug target pathways : 110
Takayasu arteritis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 40 | Takayasu arteritis | - |
| 46 | Malignant rheumatoid arthritis | 25.000 |
| 96 | Crohn disease | 21.412 |
| 49 | Systemic lupus erythematosus | 19.869 |
| 41 | Giant cell arteritis | 17.065 |
| 51 | Scleroderma | 15.207 |
| 97 | Ulcerative colitis | 15.046 |
| 53 | Sjogren syndrome | 14.609 |
| 65 | Primary immunodeficiency | 13.968 |
| 50 | Dermatomyositis | 13.487 |
| 11 | Myasthenia gravis | 12.288 |
| 162 | Pemphigoid | 11.727 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 11.267 |
| 42 | Polyarteritis nodosa | 11.157 |
| 269 | Pyogenic arthritis | 10.752 |
| 107 | Juvenile idiopathic arthritis | 10.731 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 10.586 |
| 271 | Ankylosing spondylitis | 9.943 |
| 60 | Aplastic anemia | 9.893 |
| 93 | Primary biliary cholangitis | 9.078 |
| 56 | Behcet disease | 9.013 |
| 44 | Wegener granulomatosis | 8.067 |
| 286 | Hereditary sideroblastic anemia | 8.000 |
| 19 | Lysosomal storage disease | 7.936 |
| 284 | Diamond-Blackfan anemia | 7.920 |
| 326 | Osteopetrosis | 7.750 |
| 55 | Relapsing polychondritis | 7.560 |
| 283 | Acquired pure red cell aplasia | 7.333 |
| 285 | Fanconi anemia | 7.099 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 6.857 |
| 164 | Oculocutaneous albinism | 6.833 |
| 84 | Sarcoidosis | 6.673 |
| 85 | Idiopathic interstitial pneumonia | 6.516 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 6.187 |
| 160 | Congenital ichthyosis | 6.120 |
| 151 | Rasmussen encephalitis | 6.000 |
| 43 | Microscopic polyangiitis | 5.669 |
| 20 | Adrenoleukodystrophy | 5.596 |
| 38 | Stevens-Johnson syndrome | 5.461 |
| 39 | Toxic epidermal necrolysis | 5.167 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.938 |
| 228 | Bronchiolitis obliterans | 4.811 |
| 26 | HTLV-1-associated myelopathy | 4.604 |
| 6 | Parkinson disease | 4.319 |
| 224 | Purpura nephritis | 4.312 |
| 28 | Systemic amyloidosis | 4.025 |
| 95 | Autoimmune hepatitis | 3.817 |
| 2 | Amyotrophic lateral sclerosis | 3.541 |
| 36 | Epidermolysis bullosa | 3.448 |
| 61 | Autoimmune hemolytic anemia | 3.371 |
| 222 | Primary nephrotic syndrome | 3.273 |
| 64 | Thrombotic thrombocytopenic purpura | 3.150 |
| 256 | Muscle glycogenosis | 3.098 |
| 66 | IgA nephropathy | 2.968 |
| 270 | Chronic recurrent multifocal osteomyelitis | 2.880 |
| 227 | Osler disease | 2.630 |
| 113 | Muscular dystrophy | 2.558 |
| 274 | Osteogenesis Imperfecta | 2.429 |
| 331 | Idiopathic multicentric castleman disease | 2.323 |
| 63 | Idiopathic thrombocytopenic purpura | 2.048 |
| 58 | Hypertrophic cardiomyopathy | 2.010 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 90 | Retinitis pigmentosa | 1.998 |
| 16 | Crow-Fukase syndrome | 1.944 |
| 35 | Pemphigus | 1.909 |
| 299 | Cystic fibrosis | 1.725 |
| 158 | Tuberous sclerosis | 1.571 |
| 25 | Progressive multifocal leukoencephalopathy | 1.491 |
| 172 | Hypophosphatasia | 1.387 |
| 298 | Hereditary pancreatitis | 1.377 |
| 37 | Generalised pustular psoriasis | 1.312 |
| 10 | Charcot-Marie-Tooth disease | 1.080 |
| 54 | Adult still disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |