45. Eosinophilic granulomatosis with Polyangiitis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 31 / Drugs : 44 - (DrugBank : 18) / Drug target genes : 18 - Drug target pathways : 101
Eosinophilic granulomatosis with Polyangiitis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 45 | Eosinophilic granulomatosis with Polyangiitis | - |
| 42 | Polyarteritis nodosa | 15.316 |
| 96 | Crohn disease | 14.392 |
| 46 | Malignant rheumatoid arthritis | 14.376 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 14.329 |
| 51 | Scleroderma | 12.832 |
| 162 | Pemphigoid | 12.209 |
| 41 | Giant cell arteritis | 12.209 |
| 284 | Diamond-Blackfan anemia | 11.523 |
| 85 | Idiopathic interstitial pneumonia | 11.329 |
| 40 | Takayasu arteritis | 11.267 |
| 285 | Fanconi anemia | 10.954 |
| 283 | Acquired pure red cell aplasia | 10.667 |
| 60 | Aplastic anemia | 10.507 |
| 19 | Lysosomal storage disease | 10.069 |
| 65 | Primary immunodeficiency | 9.910 |
| 49 | Systemic lupus erythematosus | 9.801 |
| 97 | Ulcerative colitis | 9.717 |
| 164 | Oculocutaneous albinism | 9.412 |
| 11 | Myasthenia gravis | 9.067 |
| 44 | Wegener granulomatosis | 8.963 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 8.963 |
| 53 | Sjogren syndrome | 8.873 |
| 226 | Interstitial cystitis with Hunners ulcer | 8.750 |
| 43 | Microscopic polyangiitis | 8.730 |
| 93 | Primary biliary cholangitis | 8.067 |
| 55 | Relapsing polychondritis | 7.875 |
| 6 | Parkinson disease | 6.973 |
| 56 | Behcet disease | 6.790 |
| 95 | Autoimmune hepatitis | 6.632 |
| 50 | Dermatomyositis | 6.481 |
| 286 | Hereditary sideroblastic anemia | 6.465 |
| 36 | Epidermolysis bullosa | 6.463 |
| 222 | Primary nephrotic syndrome | 6.284 |
| 28 | Systemic amyloidosis | 6.229 |
| 61 | Autoimmune hemolytic anemia | 6.120 |
| 151 | Rasmussen encephalitis | 6.000 |
| 224 | Purpura nephritis | 5.926 |
| 38 | Stevens-Johnson syndrome | 5.926 |
| 2 | Amyotrophic lateral sclerosis | 5.814 |
| 228 | Bronchiolitis obliterans | 5.727 |
| 66 | IgA nephropathy | 5.657 |
| 39 | Toxic epidermal necrolysis | 5.444 |
| 107 | Juvenile idiopathic arthritis | 5.279 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 5.218 |
| 20 | Adrenoleukodystrophy | 5.172 |
| 35 | Pemphigus | 5.172 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 269 | Pyogenic arthritis | 4.719 |
| 64 | Thrombotic thrombocytopenic purpura | 4.594 |
| 326 | Osteopetrosis | 4.594 |
| 26 | HTLV-1-associated myelopathy | 4.491 |
| 274 | Osteogenesis Imperfecta | 3.714 |
| 63 | Idiopathic thrombocytopenic purpura | 3.388 |
| 160 | Congenital ichthyosis | 3.333 |
| 113 | Muscular dystrophy | 3.230 |
| 84 | Sarcoidosis | 3.087 |
| 227 | Osler disease | 3.043 |
| 299 | Cystic fibrosis | 3.034 |
| 331 | Idiopathic multicentric castleman disease | 2.774 |
| 300 | IgG4-related disease | 2.593 |
| 271 | Ankylosing spondylitis | 2.585 |
| 58 | Hypertrophic cardiomyopathy | 2.500 |
| 90 | Retinitis pigmentosa | 2.490 |
| 94 | Primary sclerosing cholangitis | 2.339 |
| 16 | Crow-Fukase syndrome | 2.000 |
| 158 | Tuberous sclerosis | 1.905 |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.750 |
| 298 | Hereditary pancreatitis | 1.730 |
| 172 | Hypophosphatasia | 1.407 |
| 256 | Muscle glycogenosis | 1.290 |
| 98 | Eosinophilic gastrointestinal disease | 1.192 |
| 10 | Charcot-Marie-Tooth disease | 1.182 |
| 70 | Spinal stenosis | 1.077 |
| 34 | Neurofibromatosis | 1.032 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |