53. Sjogren syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 448 / Drugs : 436 - (DrugBank : 104) / Drug target genes : 68 - Drug target pathways : 185
Sjogren syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 53 | Sjogren syndrome | - |
| 46 | Malignant rheumatoid arthritis | 35.799 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 29.318 |
| 49 | Systemic lupus erythematosus | 26.180 |
| 96 | Crohn disease | 23.645 |
| 65 | Primary immunodeficiency | 19.708 |
| 51 | Scleroderma | 18.809 |
| 97 | Ulcerative colitis | 18.071 |
| 107 | Juvenile idiopathic arthritis | 17.920 |
| 162 | Pemphigoid | 16.279 |
| 41 | Giant cell arteritis | 16.279 |
| 50 | Dermatomyositis | 16.030 |
| 11 | Myasthenia gravis | 15.253 |
| 40 | Takayasu arteritis | 14.609 |
| 226 | Interstitial cystitis with Hunners ulcer | 14.427 |
| 271 | Ankylosing spondylitis | 13.481 |
| 84 | Sarcoidosis | 13.372 |
| 2 | Amyotrophic lateral sclerosis | 13.346 |
| 60 | Aplastic anemia | 13.333 |
| 285 | Fanconi anemia | 13.156 |
| 93 | Primary biliary cholangitis | 12.118 |
| 55 | Relapsing polychondritis | 12.000 |
| 160 | Congenital ichthyosis | 11.681 |
| 38 | Stevens-Johnson syndrome | 11.676 |
| 269 | Pyogenic arthritis | 11.676 |
| 19 | Lysosomal storage disease | 10.962 |
| 44 | Wegener granulomatosis | 10.521 |
| 284 | Diamond-Blackfan anemia | 10.205 |
| 95 | Autoimmune hepatitis | 9.865 |
| 56 | Behcet disease | 9.697 |
| 36 | Epidermolysis bullosa | 9.329 |
| 39 | Toxic epidermal necrolysis | 9.256 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 8.873 |
| 26 | HTLV-1-associated myelopathy | 8.397 |
| 28 | Systemic amyloidosis | 8.280 |
| 42 | Polyarteritis nodosa | 8.036 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 7.979 |
| 6 | Parkinson disease | 7.821 |
| 283 | Acquired pure red cell aplasia | 7.578 |
| 299 | Cystic fibrosis | 7.334 |
| 300 | IgG4-related disease | 7.273 |
| 61 | Autoimmune hemolytic anemia | 7.121 |
| 228 | Bronchiolitis obliterans | 6.983 |
| 164 | Oculocutaneous albinism | 6.868 |
| 113 | Muscular dystrophy | 6.864 |
| 222 | Primary nephrotic syndrome | 6.773 |
| 86 | Pulmonary arterial hypertension | 6.470 |
| 43 | Microscopic polyangiitis | 6.312 |
| 256 | Muscle glycogenosis | 6.250 |
| 286 | Hereditary sideroblastic anemia | 6.236 |
| 151 | Rasmussen encephalitis | 6.000 |
| 224 | Purpura nephritis | 5.989 |
| 66 | IgA nephropathy | 5.835 |
| 64 | Thrombotic thrombocytopenic purpura | 5.707 |
| 35 | Pemphigus | 5.537 |
| 63 | Idiopathic thrombocytopenic purpura | 5.120 |
| 85 | Idiopathic interstitial pneumonia | 5.039 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 37 | Generalised pustular psoriasis | 4.860 |
| 326 | Osteopetrosis | 4.582 |
| 20 | Adrenoleukodystrophy | 4.552 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 4.455 |
| 227 | Osler disease | 4.418 |
| 270 | Chronic recurrent multifocal osteomyelitis | 4.242 |
| 83 | Addison disease | 4.242 |
| 58 | Hypertrophic cardiomyopathy | 4.217 |
| 1 | Spinal and bulbar muscular atrophy | 3.862 |
| 94 | Primary sclerosing cholangitis | 3.142 |
| 98 | Eosinophilic gastro-intestinal disorder | 3.125 |
| 168 | Ehlers-Danlos syndrome | 2.980 |
| 296 | Biliary atresia | 2.978 |
| 274 | Osteogenesis Imperfecta | 2.945 |
| 156 | Rett syndrome | 2.881 |
| 90 | Retinitis pigmentosa | 2.855 |
| 298 | Hereditary pancreatitis | 2.751 |
| 10 | Charcot-Marie-Tooth disease | 2.521 |
| 331 | Idiopathic multicentric castleman disease | 2.270 |
| 34 | Neurofibromatosis | 2.251 |
| 231 | Alpha-1-antitrypsin deficiency | 2.113 |
| 158 | Tuberous sclerosis | 2.113 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 127 | Frontotemporal lobar degeneration | 1.960 |
| 159 | Xeroderma pigmentosum | 1.865 |
| 114 | Non-dystrophic myotonia syndrome | 1.717 |
| 254 | Porphyria | 1.651 |
| 76 | Pituitary gonadotropin secretion hyperthyroidism | 1.582 |
| 70 | Spinal stenosis | 1.539 |
| 25 | Progressive multifocal leukoencephalopathy | 1.379 |
| 172 | Hypophosphatasia | 1.358 |
| 5 | Progressive supranuclear palsy | 1.148 |
| 235 | Hypoparathyroidism | 1.036 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |