66. IgA nephropathy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 407 / Drugs : 342 - (DrugBank : 73) / Drug target genes : 40 - Drug target pathways : 146
IgA nephropathy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 66 | IgA nephropathy | - |
| 46 | Malignant rheumatoid arthritis | 21.729 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 21.455 |
| 49 | Systemic lupus erythematosus | 20.839 |
| 222 | Primary nephrotic syndrome | 18.088 |
| 96 | Crohn disease | 13.650 |
| 224 | Purpura nephritis | 13.440 |
| 61 | Autoimmune hemolytic anemia | 11.571 |
| 19 | Lysosomal storage disease | 10.411 |
| 97 | Ulcerative colitis | 10.358 |
| 6 | Parkinson disease | 10.094 |
| 51 | Scleroderma | 9.572 |
| 283 | Acquired pure red cell aplasia | 9.371 |
| 162 | Pemphigoid | 9.164 |
| 85 | Idiopathic interstitial pneumonia | 8.718 |
| 2 | Amyotrophic lateral sclerosis | 8.122 |
| 50 | Dermatomyositis | 8.050 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 7.408 |
| 11 | Myasthenia gravis | 7.189 |
| 228 | Bronchiolitis obliterans | 6.982 |
| 65 | Primary immunodeficiency | 6.907 |
| 93 | Primary biliary cholangitis | 6.818 |
| 60 | Aplastic anemia | 6.367 |
| 63 | Idiopathic thrombocytopenic purpura | 6.217 |
| 284 | Diamond-Blackfan anemia | 6.104 |
| 64 | Thrombotic thrombocytopenic purpura | 6.075 |
| 107 | Juvenile idiopathic arthritis | 5.934 |
| 53 | Sjogren syndrome | 5.835 |
| 56 | Behcet disease | 5.762 |
| 113 | Muscular dystrophy | 5.718 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 5.657 |
| 95 | Autoimmune hepatitis | 5.481 |
| 285 | Fanconi anemia | 5.238 |
| 36 | Epidermolysis bullosa | 5.150 |
| 299 | Cystic fibrosis | 5.100 |
| 41 | Giant cell arteritis | 5.022 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 164 | Oculocutaneous albinism | 4.958 |
| 28 | Systemic amyloidosis | 4.714 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 4.667 |
| 42 | Polyarteritis nodosa | 4.629 |
| 84 | Sarcoidosis | 4.469 |
| 86 | Pulmonary arterial hypertension | 4.287 |
| 151 | Rasmussen encephalitis | 4.286 |
| 218 | Alport syndrome | 4.286 |
| 274 | Osteogenesis Imperfecta | 4.200 |
| 20 | Adrenoleukodystrophy | 4.073 |
| 269 | Pyogenic arthritis | 4.013 |
| 226 | Interstitial cystitis with Hunners ulcer | 3.973 |
| 39 | Toxic epidermal necrolysis | 3.740 |
| 58 | Hypertrophic cardiomyopathy | 3.568 |
| 55 | Relapsing polychondritis | 3.514 |
| 286 | Hereditary sideroblastic anemia | 3.393 |
| 158 | Tuberous sclerosis | 3.239 |
| 43 | Microscopic polyangiitis | 3.159 |
| 26 | HTLV-1-associated myelopathy | 3.128 |
| 271 | Ankylosing spondylitis | 3.033 |
| 38 | Stevens-Johnson syndrome | 3.017 |
| 300 | IgG4-related disease | 3.017 |
| 109 | Atypical hemolytic uremic syndrome | 3.000 |
| 40 | Takayasu arteritis | 2.968 |
| 326 | Osteopetrosis | 2.893 |
| 160 | Congenital ichthyosis | 2.686 |
| 44 | Wegener granulomatosis | 2.449 |
| 35 | Pemphigus | 2.384 |
| 90 | Retinitis pigmentosa | 2.200 |
| 17 | Multiple system atrophy | 2.043 |
| 257 | Hepatic glycogenosis | 2.000 |
| 16 | Crow-Fukase syndrome | 1.903 |
| 211 | Hypoplastic left heart syndrome | 1.903 |
| 94 | Primary sclerosing cholangitis | 1.842 |
| 227 | Osler disease | 1.646 |
| 14 | Chronic inflammatory demyelinating polyneuropathy | 1.638 |
| 83 | Addison disease | 1.629 |
| 88 | Chronic thromboembolic pulmonary hypertension | 1.547 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.244 |
| 57 | Idiopathic dilated cardiomyopathy | 1.171 |
| 167 | Marfan syndrome | 1.080 |
| 75 | Cushing disease | 1.060 |
| 333 | Hutchinson-Gilford syndrome | 1.057 |
| 91 | Budd-Chiari syndrome | 1.057 |
| 235 | Hypoparathyroidism | 1.057 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |