67. Polycystic kidney disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 251 / Drugs : 278 - (DrugBank : 69) / Drug target genes : 97 - Drug target pathways : 182
Polycystic kidney disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 67 | Polycystic kidney disease | - |
| 86 | Pulmonary arterial hypertension | 16.009 |
| 6 | Parkinson disease | 13.821 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 7.294 |
| 96 | Crohn disease | 5.895 |
| 81 | Congenital adrenal hyperplasia | 5.895 |
| 58 | Hypertrophic cardiomyopathy | 5.842 |
| 75 | Cushing disease | 5.379 |
| 167 | Marfan syndrome | 5.287 |
| 46 | Malignant rheumatoid arthritis | 5.048 |
| 57 | Idiopathic dilated cardiomyopathy | 4.316 |
| 299 | Cystic fibrosis | 4.080 |
| 85 | Idiopathic interstitial pneumonia | 4.053 |
| 51 | Scleroderma | 3.945 |
| 97 | Ulcerative colitis | 3.785 |
| 89 | Lymphangioleiomyomatosis | 3.556 |
| 225 | Congenital nephrogenic diabetes insipidus | 3.368 |
| 113 | Muscular dystrophy | 3.179 |
| 74 | Prolactin secreting pituitary adenoma | 2.842 |
| 218 | Alport syndrome | 2.807 |
| 210 | Single Ventricle | 2.539 |
| 17 | Multiple system atrophy | 2.513 |
| 2 | Amyotrophic lateral sclerosis | 2.491 |
| 70 | Spinal stenosis | 2.450 |
| 127 | Frontotemporal lobar degeneration | 2.289 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 2.209 |
| 272 | Fibrodysplasia ossificans progressiva | 2.113 |
| 193 | Prader-Willi syndrome | 2.073 |
| 169 | Menkes disease | 2.012 |
| 170 | Occipital horn syndrome | 2.012 |
| 77 | Growth hormone secreting pituitary adenoma | 2.000 |
| 263 | Cerebrotendinous xanthomatosis | 2.000 |
| 28 | Systemic amyloidosis | 1.895 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.864 |
| 8 | Huntington disease | 1.765 |
| 34 | Neurofibromatosis | 1.749 |
| 78 | Hypopituitarism | 1.636 |
| 298 | Hereditary pancreatitis | 1.519 |
| 206 | Fragile X syndrome | 1.509 |
| 265 | Lipodystrophy | 1.493 |
| 222 | Primary nephrotic syndrome | 1.444 |
| 310 | Congenital anomalies syndrome | 1.368 |
| 158 | Tuberous sclerosis | 1.278 |
| 118 | Myelomeningocele | 1.273 |
| 49 | Systemic lupus erythematosus | 1.213 |
| 94 | Primary sclerosing cholangitis | 1.175 |
| 227 | Osler disease | 1.043 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |