84. Sarcoidosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 149 / Drugs : 202 - (DrugBank : 78) / Drug target genes : 66 - Drug target pathways : 169
Sarcoidosis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 84 | Sarcoidosis | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 60.899 |
| 46 | Malignant rheumatoid arthritis | 46.346 |
| 6 | Parkinson disease | 35.677 |
| 97 | Ulcerative colitis | 34.778 |
| 96 | Crohn disease | 33.784 |
| 296 | Biliary atresia | 23.659 |
| 51 | Scleroderma | 23.344 |
| 34 | Neurofibromatosis | 21.876 |
| 50 | Dermatomyositis | 21.581 |
| 2 | Amyotrophic lateral sclerosis | 20.032 |
| 36 | Epidermolysis bullosa | 17.666 |
| 107 | Juvenile idiopathic arthritis | 17.122 |
| 152 | PCDH19 related syndrome | 16.000 |
| 298 | Hereditary pancreatitis | 15.819 |
| 8 | Huntington disease | 15.707 |
| 193 | Prader-Willi syndrome | 15.013 |
| 18 | Spinocerebellar degeneration | 14.909 |
| 231 | Alpha-1-antitrypsin deficiency | 14.751 |
| 21 | Mitochondrial disease | 14.550 |
| 271 | Ankylosing spondylitis | 14.540 |
| 205 | Fragile X syndrome related disease | 14.066 |
| 41 | Giant cell arteritis | 14.043 |
| 53 | Sjogren syndrome | 13.372 |
| 145 | West syndrome | 13.317 |
| 70 | Spinal stenosis | 13.197 |
| 201 | Angelman syndrome | 12.488 |
| 158 | Tuberous sclerosis | 12.327 |
| 49 | Systemic lupus erythematosus | 12.294 |
| 98 | Eosinophilic gastrointestinal disease | 12.255 |
| 140 | Dorabe syndrome | 12.213 |
| 144 | Lennox-Gastaut syndrome | 12.073 |
| 162 | Pemphigoid | 11.614 |
| 156 | Rett syndrome | 11.394 |
| 272 | Fibrodysplasia ossificans progressiva | 11.047 |
| 56 | Behcet disease | 10.976 |
| 75 | Cushing disease | 10.669 |
| 22 | Moyamoya disease | 10.481 |
| 155 | Acquired aphasia with convulsive disorder | 10.227 |
| 17 | Multiple system atrophy | 9.836 |
| 206 | Fragile X syndrome | 9.539 |
| 44 | Wegener granulomatosis | 8.833 |
| 65 | Primary immunodeficiency | 8.238 |
| 93 | Primary biliary cholangitis | 7.997 |
| 3 | Spinal muscular atrophy | 7.847 |
| 222 | Primary nephrotic syndrome | 7.280 |
| 86 | Pulmonary arterial hypertension | 7.176 |
| 164 | Oculocutaneous albinism | 7.171 |
| 40 | Takayasu arteritis | 6.673 |
| 256 | Muscle glycogenosis | 6.648 |
| 58 | Hypertrophic cardiomyopathy | 6.574 |
| 228 | Bronchiolitis obliterans | 6.370 |
| 226 | Interstitial cystitis with Hunners ulcer | 6.341 |
| 5 | Progressive supranuclear palsy | 6.292 |
| 85 | Idiopathic interstitial pneumonia | 5.838 |
| 60 | Aplastic anemia | 5.447 |
| 299 | Cystic fibrosis | 5.268 |
| 11 | Myasthenia gravis | 5.221 |
| 43 | Microscopic polyangiitis | 4.906 |
| 269 | Pyogenic arthritis | 4.631 |
| 66 | IgA nephropathy | 4.469 |
| 55 | Relapsing polychondritis | 4.332 |
| 284 | Diamond-Blackfan anemia | 4.266 |
| 28 | Systemic amyloidosis | 4.216 |
| 285 | Fanconi anemia | 4.146 |
| 19 | Lysosomal storage disease | 4.122 |
| 88 | Chronic thromboembolic pulmonary hypertension | 4.045 |
| 106 | Cryopyrin-associated periodic syndrome | 4.000 |
| 113 | Muscular dystrophy | 3.840 |
| 94 | Primary sclerosing cholangitis | 3.820 |
| 265 | Lipodystrophy | 3.761 |
| 38 | Stevens-Johnson syndrome | 3.585 |
| 300 | IgG4-related disease | 3.585 |
| 35 | Pemphigus | 3.406 |
| 211 | Hypoplastic left heart syndrome | 3.239 |
| 283 | Acquired pure red cell aplasia | 3.087 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 3.087 |
| 160 | Congenital ichthyosis | 3.087 |
| 42 | Polyarteritis nodosa | 3.002 |
| 95 | Autoimmune hepatitis | 2.956 |
| 168 | Ehlers-Danlos syndrome | 2.913 |
| 37 | Generalised pustular psoriasis | 2.838 |
| 47 | Buerger disease | 2.732 |
| 224 | Purpura nephritis | 2.663 |
| 1 | Spinal and bulbar muscular atrophy | 2.652 |
| 331 | Idiopathic multicentric castleman disease | 2.644 |
| 78 | Hypopituitarism | 2.627 |
| 10 | Charcot-Marie-Tooth disease | 2.439 |
| 15 | Inclusion body myositis | 2.439 |
| 127 | Frontotemporal lobar degeneration | 2.224 |
| 63 | Idiopathic thrombocytopenic purpura | 2.064 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 2.028 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 263 | Cerebrotendinous xanthomatosis | 2.000 |
| 266 | Familial mediterranean fever | 1.982 |
| 114 | Non-dystrophic myotonia syndrome | 1.609 |
| 270 | Chronic recurrent multifocal osteomyelitis | 1.555 |
| 218 | Alport syndrome | 1.555 |
| 83 | Addison disease | 1.555 |
| 20 | Adrenoleukodystrophy | 1.372 |
| 171 | Wilson disease | 1.350 |
| 310 | Congenital anomalies syndrome | 1.350 |
| 172 | Hypophosphatasia | 1.350 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 1.282 |
| 61 | Autoimmune hemolytic anemia | 1.244 |
| 212 | Tricuspid atresia | 1.194 |
| 246 | Methylmalonic acidemia | 1.090 |
| 225 | Congenital nephrogenic diabetes insipidus | 1.087 |
| 79 | Homozygous familial hypercholesterolemia | 1.073 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.041 |
| 235 | Hypoparathyroidism | 1.024 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 108 | TNF receptor-associated periodic syndrome | 1.000 |
| 267 | Hyper-IgD syndrome | 1.000 |
| 317 | Trifunctional protein deficiency | 1.000 |
| 54 | Adult still disease | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |