94. Primary sclerosing cholangitis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 189 / Drugs : 159 - (DrugBank : 46) / Drug target genes : 22 - Drug target pathways : 148
Primary sclerosing cholangitis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 94 | Primary sclerosing cholangitis | - |
| 96 | Crohn disease | 7.895 |
| 46 | Malignant rheumatoid arthritis | 7.866 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 6.560 |
| 49 | Systemic lupus erythematosus | 5.679 |
| 93 | Primary biliary cholangitis | 4.427 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 4.053 |
| 20 | Adrenoleukodystrophy | 3.986 |
| 84 | Sarcoidosis | 3.820 |
| 51 | Scleroderma | 3.696 |
| 97 | Ulcerative colitis | 3.628 |
| 2 | Amyotrophic lateral sclerosis | 3.584 |
| 63 | Idiopathic thrombocytopenic purpura | 3.267 |
| 53 | Sjogren syndrome | 3.142 |
| 222 | Primary nephrotic syndrome | 3.086 |
| 284 | Diamond-Blackfan anemia | 3.014 |
| 65 | Primary immunodeficiency | 2.923 |
| 285 | Fanconi anemia | 2.716 |
| 162 | Pemphigoid | 2.641 |
| 43 | Microscopic polyangiitis | 2.632 |
| 164 | Oculocutaneous albinism | 2.619 |
| 300 | IgG4-related disease | 2.544 |
| 60 | Aplastic anemia | 2.481 |
| 36 | Epidermolysis bullosa | 2.397 |
| 160 | Congenital ichthyosis | 2.339 |
| 283 | Acquired pure red cell aplasia | 2.339 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 2.339 |
| 75 | Cushing disease | 2.292 |
| 95 | Autoimmune hepatitis | 2.285 |
| 19 | Lysosomal storage disease | 2.252 |
| 35 | Pemphigus | 2.153 |
| 299 | Cystic fibrosis | 2.151 |
| 85 | Idiopathic interstitial pneumonia | 2.144 |
| 61 | Autoimmune hemolytic anemia | 2.053 |
| 42 | Polyarteritis nodosa | 2.024 |
| 263 | Cerebrotendinous xanthomatosis | 2.000 |
| 39 | Toxic epidermal necrolysis | 1.990 |
| 15 | Inclusion body myositis | 1.990 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 1.895 |
| 66 | IgA nephropathy | 1.842 |
| 11 | Myasthenia gravis | 1.725 |
| 28 | Systemic amyloidosis | 1.595 |
| 86 | Pulmonary arterial hypertension | 1.500 |
| 44 | Wegener granulomatosis | 1.444 |
| 6 | Parkinson disease | 1.414 |
| 310 | Congenital anomalies syndrome | 1.404 |
| 229 | Autoimmune pulmonary alveolar proteinosis | 1.404 |
| 265 | Lipodystrophy | 1.328 |
| 79 | Homozygous familial hypercholesterolemia | 1.316 |
| 331 | Idiopathic multicentric castleman disease | 1.250 |
| 228 | Bronchiolitis obliterans | 1.225 |
| 56 | Behcet disease | 1.193 |
| 67 | Polycystic kidney disease | 1.175 |
| 271 | Ankylosing spondylitis | 1.150 |
| 296 | Biliary atresia | 1.123 |
| 298 | Hereditary pancreatitis | 1.080 |
| 226 | Interstitial cystitis with Hunners ulcer | 1.039 |
| 324 | Methylglutaconic aciduria | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |