Dimethyl Fumarate (DMF)

( DrugBank: Dimethyl fumarate / KEGG DRUG: Dimethyl fumarate )

3 diseases

ID	Disease name (Link within this page)	Number of trials
13	Multiple sclerosis/Neuromyelitis optica	4
51	Scleroderma	1

ID	Disease name (Link within this page)	Number of trials
86	Pulmonary arterial hypertension	1

13. Multiple sclerosis/Neuromyelitis optica

Clinical trials : 3,340 / Drugs : 2,163 - (DrugBank : 383) / Drug target genes : 241 - Drug target pathways : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05658484 (ClinicalTrials.gov)	April 13, 2023	12/12/2022	A Study of Dimethyl Fumarate (DMF)in Relapsing Forms of Multiple Sclerosis (RMS) Participants in Chi ...	A Multicenter, Postmarketing Study of Dimethyl Fumarate (Tecfidera; BG00012) in Relapsing Forms of M ...	Multiple Sclerosis	Drug: Dimethyl fumarate	Biogen	NULL	Not yet recruiting	18 Years	65 Years	All	60	Phase 4	NULL
2	NCT04468165 (ClinicalTrials.gov)	February 23, 2021	8/7/2020	Effectiveness and Safety of Generic Delayed-Release Dimethyl Fumarate (Sclera® or Marovarex ®, Hikma ...	Effectiveness and Safety of Generic Delayed-Release Dimethyl Fumarate (Sclera® or Marovarex ®, Hikma ...	Relapsing Remitting Multiple Sclerosis	Drug: Dimethyl Fumarate (DMF)	Hikma Pharmaceuticals LLC	NULL	Active, not recruiting	18 Years	N/A	All	155		Algeria;Egypt;Jordan
3	NCT03101735 (ClinicalTrials.gov)	September 23, 2016	3/3/2017	Study to Assess Resource Utilization and Quality of Life of Patients With RRMS Treated With Tecfider ...	A Real Life, Non-interventional, Multicentre Study to Assess Resource Utilization and Quality of Lif ...	RRMS	Drug: Dimethyl Fumarate (DMF)	Genesis Pharma CNS & Specialty	NULL	Completed	18 Years	65 Years	All	455		Greece
4	EUCTR2015-004116-38-SE (EUCTR)	18/12/2015	20/10/2015	A clincial study comparing the effectiveness of two drugs, named Rituximab and Dimethyl Fumarate (Te ...	RItuximab versus FUmarate in Newly Diagnosed Multiple Sclerosis – RIFUND-MSA randomized phase 3 stud ...	Patients with multiple sclerosis (MS) or patients presenting with symptoms highly suspicious of MS w ...	Trade Name: Mabthera INN or Proposed INN: RITUXIMAB Trade Name: Tecfidera INN or Proposed INN: DIMETHYL ...	Department of Clinical Sciences, Danderyd Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	200	Phase 3	Sweden

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51. Scleroderma

Clinical trials : 525 / Drugs : 565 - (DrugBank : 148) / Drug target genes : 114 - Drug target pathways : 217

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02981082 (ClinicalTrials.gov)	December 2016	30/11/2016	Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension	A Double-blinded, Placebo-controlled Pilot Study of Dimethyl Fumarate (DMF)in Pulmonary Arterial Hyp ...	Systemic Sclerosis;Pulmonary; Hypertension	Drug: Dimethyl Fumarate (DMF);Drug: Placebo Oral Tablet	Robert Lafyatis	Biogen	Terminated	18 Years	80 Years	All	6	Phase 1	United States

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86. Pulmonary arterial hypertension

Clinical trials : 1,205 / Drugs : 684 - (DrugBank : 124) / Drug target genes : 100 - Drug target pathways : 193

trials per page:

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02981082 (ClinicalTrials.gov)	December 2016	30/11/2016	Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial Hypertension	A Double-blinded, Placebo-controlled Pilot Study of Dimethyl Fumarate (DMF)in Pulmonary Arterial Hyp ...	Systemic Sclerosis;Pulmonary; Hypertension	Drug: Dimethyl Fumarate (DMF);Drug: Placebo Oral Tablet	Robert Lafyatis	Biogen	Terminated	18 Years	80 Years	All	6	Phase 1	United States

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