Xenon

( DrugBank: Xenon / KEGG DRUG: Xenon, Xenon Xe 133 )

3 diseases

ID	Disease name (Link within this page)	Number of trials
22	Moyamoya disease	1
85	Idiopathic interstitial pneumonia	3

ID	Disease name (Link within this page)	Number of trials
299	Cystic fibrosis	6

22. Moyamoya disease

Clinical trials : 17 / Drugs : 22 - (DrugBank : 17) / Drug target genes : 33 - Drug target pathways : 45

trials per page:

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01419275 (ClinicalTrials.gov)	April 2009	16/8/2011	Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients	Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients	Cerebrovascular Accident;Moyamoya Disease	Drug: Xenon contrast agent;Device: Magnetic Resonance Imaging	Stanford University	NULL	Completed	N/A	N/A	All	126	N/A	United States

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85. Idiopathic interstitial pneumonia

Clinical trials : 627 / Drugs : 443 - (DrugBank : 120) / Drug target genes : 99 - Drug target pathways : 212

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05241275 (ClinicalTrials.gov)	July 19, 2022	3/2/2022	Xenon MRI and Progressive ILD	XENON ILD: 129Xe MRI to Evaluate aNtifibrotic respOnse and progressioN in ILD	Idiopathic Pulmonary Fibrosis;Progressive Pulmonary Fibrosis	Drug: Hyperpolarized 129 Xenon Gas Comparing Progressive Pulmonary Fibrosis Treatment	Duke University	Boehringer Ingelheim	Recruiting	18 Years	N/A	All	75	Phase 2	United States
2	NCT04071769 (ClinicalTrials.gov)	August 3, 2020	9/8/2019	Genentech Xenon MRI Idiopathic Pulmonary Fibrosis	Using Xenon MRI to Evaluate the Efficacy of Therapies for Idiopathic Pulmonary Fibrosis	Idiopathic Pulmonary Fibrosis	Drug: Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment	Duke University	NULL	Recruiting	18 Years	N/A	All	20	Phase 2	United States
3	NCT02478268 (ClinicalTrials.gov)	May 2015	16/6/2015	Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis	Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis	Idiopathic Pulmonary Fibrosis	Drug: Hyperpolarized 129-Xenon gas;Device: MRI	Bastiaan Driehuys	University of Wisconsin, Madison;National Heart, Lung, and Blood Institute (NHLBI)	Completed	18 Years	N/A	All	64	Phase 1	United States

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299. Cystic fibrosis

Clinical trials : 1,695 / Drugs : 1,527 - (DrugBank : 268) / Drug target genes : 111 - Drug target pathways : 174

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04467957 (ClinicalTrials.gov)	November 15, 2020	19/6/2020	Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis	Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis	Cystic Fibrosis	Drug: Initiation of CFTR Modulator;Drug: Hyperpolarized Xenon 129	Children's Hospital Medical Center, Cincinnati	NULL	Active, not recruiting	6 Years	21 Years	All	26	Phase 4	United States
2	NCT03593434 (ClinicalTrials.gov)	July 30, 2018	28/6/2018	Airway Clearance Therapy on Hyperpolarized 129Xenon and MRI	The Effect of Airway Clearance Therapy on Hyperpolarized 129Xenon MRI Compared With Lung Clearance I ...	Cystic Fibrosis	Drug: hyperpolarized Xenon gas	Children's Hospital Medical Center, Cincinnati	National Heart, Lung, and Blood Institute (NHLBI)	Completed	6 Years	21 Years	All	20		United States
3	NCT03482960 (ClinicalTrials.gov)	May 29, 2018	23/3/2018	Comparison of 129Xe MRI With 19F MRI in CF Lung Disease	Comparison of 129Xe MRI With 19F MRI in CF Lung Disease	Cystic Fibrosis	Drug: Hyperpolarized Xenon gas;Drug: PFP	University of North Carolina, Chapel Hill	Cystic Fibrosis Foundation	Completed	18 Years	N/A	All	11	Early Phase 1	United States
4	NCT02848560 (ClinicalTrials.gov)	March 2016	26/7/2016	Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI	Validation of MRI as a Sensitive Tool to Longitudinally Monitor CF Lung Disease Progression and Resp ...	Cystic Fibrosis	Drug: Hyperpolarized Xenon	Children's Hospital Medical Center, Cincinnati	National Heart, Lung, and Blood Institute (NHLBI)	Active, not recruiting	6 Years	12 Years	All	38		United States
5	NCT02740868 (ClinicalTrials.gov)	August 2015	19/8/2015	Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmona ...	Development of Hyperpolarized Xenon-129 Lung Magnetic Resonance Imaging: Comparative Pilot Study of ...	Cystic Fibrosis;Asthma	Drug: Xenon-129;Device: Magnetic Resonance Imaging;Device: Lung Clearance Index	The Hospital for Sick Children	NULL	Recruiting	8 Years	N/A	All	30	Phase 2	Canada
6	EUCTR2019-003052-36-GB (EUCTR)		28/02/2020	Magnetic Resonance Imaging (MRI) in Bronchiectasis	Triple Modality Functional Magnetic Resonance Lung Imaging in Cystic Fibrosis and Non-CF Bronchiecta ...	Cystic fibrosis (CF) Non-CF Bronchiectasis MedDRA version: 21.0;Level: PT;Classification code 100064 ...	Trade Name: hyperpolarized xenon-129 Product Name: hyperpolarized xenon-129	The University of Nottingham	NULL	NA			Female: yes Male: yes	40	Phase 2	United Kingdom

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