Methionine

( DrugBank: Methionine / KEGG DRUG: Methionine )

6 diseases

ID	Disease name (Link within this page)	Number of trials
34	Neurofibromatosis	1
84	Sarcoidosis	2
93	Primary biliary cholangitis	2

ID	Disease name (Link within this page)	Number of trials
229	Autoimmune pulmonary alveolar proteinosis	1
298	Hereditary pancreatitis	1
300	IgG4-related disease	1

34. Neurofibromatosis

Clinical trials : 133 / Drugs : 186 - (DrugBank : 67) / Drug target genes : 79 - Drug target pathways : 190

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-019759-23-GB (EUCTR)	12/01/2011	13/12/2010	Evaluation of [11C]-methioninepositron emission computerised tomography (PET CT) in diagnosing neuro ...	Evaluation of [11C]-methioninepositron emission computerised tomography (PET CT) in diagnosing neuro ...	The diagnosis of malignant peripheral nerve sheath tumours in patients with neurofibromatosis 1 MedD ...	Product Name: [11C]-methionine INN or Proposed INN: 2-amino-4-(methyl[11C]sulfanyl)butanoic acid Other ...	Guys' and St. Thomas' NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes			United Kingdom

Clinical trials : 149 / Drugs : 202 - (DrugBank : 78) / Drug target genes : 66 - Drug target pathways : 169

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02824419 (ClinicalTrials.gov)	May 2016	27/5/2016	Imaging of Active Granulomas With [18F]FDG and Selected Inflammatory PET Tracers in Pulmonary Sarcoi ...	Imaging of Active Granulomas With [18F]FDG and Selected Inflammatory PET Tracers in Pulmonary Sarcoi ...	Pulmonary Sarcoidosis	Drug: Methionine;Drug: DOTANOC	Turku University Hospital	NULL	Recruiting	18 Years	N/A	Both	10	Phase 2/Phase 3	Finland
2	EUCTR2015-001815-11-FI (EUCTR)	19/04/2016	29/12/2015	PET imaging of pulmonary sarcoidosis	Imaging of active granulomas with [18F]FDG and selected inflammatory PET tracers in pulmonary sarcoi ...	Pulmonary sarcoidosis with active garnulomas in the lungs. The diagnosis is based on the clinical ev ...	Product Name: 18F-fluorodeoxyglucose Product Code: FDG INN or Proposed INN: FLUORINE (18F) FLUDEOXYGLU ...	Turku PET Centre	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Finland

Clinical trials : 298 / Drugs : 252 - (DrugBank : 59) / Drug target genes : 35 - Drug target pathways : 115

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02557360 (ClinicalTrials.gov)	November 2015	21/9/2015	Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis	Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis	Primary Biliary Cirrhosis	Dietary Supplement: S-adenosyl-L-methionine	Pomeranian Medical University Szczecin	Laval University	Completed	N/A	N/A	All	24	Phase 4	Poland
2	NCT00125281 (ClinicalTrials.gov)	July 25, 2005	29/7/2005	SAMe to Treat Biliary Cirrhosis Symptoms	S-Adenosyl Methionine for Symptomatic Treatment of Primary Biliary Cirrhosis	Liver Cirrhosis, Biliary	Drug: S-adenosyl-methionine (SAMe) capsules	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	NULL	Terminated	21 Years	N/A	All	50	Phase 2	United States

Clinical trials : 44 / Drugs : 22 - (DrugBank : 7) / Drug target genes : 3 - Drug target pathways : 14

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03887169 (ClinicalTrials.gov)	September 16, 2019	12/3/2019	Administration of Methioninein Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS ...	Oral or Enteral Administration of Methioninein Patients With Pulmonary Alveolar Proteinosis by Mutat ...	Pulmonary Alveolar Proteinosis;Mutation Ala393Thr of the MARS Gene;mutationSer567Leu of the MARS Gen ...	Drug: Methionine;Drug: Vitamin B12, B9, B6, C supplementation;Diagnostic Test: Methionine/homocystei ...	Assistance Publique - Hôpitaux de Paris	NULL	Completed	N/A	18 Years	All	3	Phase 1/Phase 2	France

Clinical trials : 95 / Drugs : 148 - (DrugBank : 51) / Drug target genes : 53 - Drug target pathways : 142

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2006-000087-83-GB (EUCTR)	19/12/2008	04/12/2007	EUROPAC2 trial to investigate the efficacy of ANTOX(vers) 1.2 and MGCT (magnesiocard) for the treatm ...	EUROPAC2 trial to investigate the efficacy of ANTOX(vers) 1.2 and MGCT (magnesiocard) for the treatm ...	Hereditary Pancreatitis and Idiopathic Chronic Pancreatitis MedDRA version: 13.1;Level: HLT;Classifi ...	Trade Name: Magnesiocard 2.5mmol Other descriptive name: MAGNESIUM ASPARTATE HYDROCHLORIDE Product Nam ...	University of Liverpool	The Royal Liverpool and Broadgreen University Hospitals NHS Trust	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	240	Phase 3	United Kingdom

Clinical trials : 40 / Drugs : 47 - (DrugBank : 21) / Drug target genes : 18 - Drug target pathways : 141

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000019908	2016/01/01	01/01/2016	Preliminary study of [11C]methionine PET/CT in the diagnosis of IgG4 related disease	Preliminary study of [11C]methioninePET/CT in the diagnosis of IgG4 related disease - Preliminary st ...	IgG4 related disease	[11C]methionine PET/CT, [18F]FDG PET/CT	Saitama Medical University International Medical Center	Saitama Medical University Hospital	Complete: follow-up complete	20years-old	Not applicable	Male and Female	30	Not selected	Japan