Biological Drug

( DrugBank: - / KEGG DRUG: - )

3 diseases

ID	Disease name (Link within this page)	Number of trials
46	Malignant rheumatoid arthritis	5
96	Crohn disease	2

ID	Disease name (Link within this page)	Number of trials
97	Ulcerative colitis	1

46. Malignant rheumatoid arthritis

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05267431 (ClinicalTrials.gov)	June 2022	14/2/2022	Outcomes of Biological Therapy on Rheumatoid Arthritis	Outcomes of Different Biological Therapy on Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: Biological Drug	Sohag University	NULL	Not yet recruiting	18 Years	N/A	All	200		Egypt
2	NCT04470453 (ClinicalTrials.gov)	October 8, 2020	9/7/2020	Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological DrugConcentr ...	Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological DrugConcentr ...	Rheumatoid Arthritis	Biological: Blood sample;Diagnostic Test: CRQ	Centre Hospitalier Universitaire de Saint Etienne	NULL	Recruiting	18 Years	N/A	All	60	Phase 4	France
3	EUCTR2019-003700-12-FR (EUCTR)	13/03/2020	04/06/2020	Association between metabolits of methotrexate and clinical response in rheumatoid arthritis patient ...	Association between methotrexate erythrocyte polyglutamate concentration and biological drugconcentr ...	rheumatoid arthritis MedDRA version: 21.0;Level: LLT;Classification code 10042952;Term: Systemic rhe ...	Product Name: Methotrexate Product Code: MTX Other descriptive name: METHOTREXATE DISODIUM Product Code ...	CHU Saint-Etienne	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	France
4	EUCTR2009-012041-35-FR (EUCTR)	27/11/2009	16/10/2009	A phase II, randomized, partially double blind, controlled study to evaluate the immunogenicity, saf ...	A phase II, randomized, partially double blind, controlled study to evaluate the immunogenicity, saf ...	Rheumatoid arthritis MedDRA version: 12.0;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Product Name: TNF-Kinoid Product Code: TNF-K	Neovacs SA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	48	Phase 2	Bulgaria;France
5	NCT03496831 (ClinicalTrials.gov)	January 1, 2006	5/4/2018	Predicting Hospitalized Infection in Patients With Chronic Inflammatory Arthritis Treated With Biolo ...	Development of a Prediction Model for the Risk of Hospitalized Infection in Patients With Chronic In ...	Rheumatoid Arthritis;Spondyloarthritis;Psoriatic Arthritis	Drug: Biologic Agents	Simon Krabbe	University of Aarhus;Zealand University Hospital;University of Southern Denmark	Completed	18 Years	N/A	All	7500		NULL

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96. Crohn disease

Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05169593 (ClinicalTrials.gov)	September 8, 2022	8/11/2021	Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic Biological ...	Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic Biological ...	Crohn Disease	Drug: Biological Drug	Universitaire Ziekenhuizen KU Leuven	NULL	Recruiting	18 Years	80 Years	All	292	Phase 4	Belgium;Italy
2	EUCTR2016-000522-18-IT (EUCTR)	24/02/2017	08/06/2021	Comparison of the effectiveness of treatment with an immunosuppressant medication over another or wi ...	Risk-stratified randomized controlled trial in paediatric Crohn¿s Disease: Methotrexate versus Azath ...	Crohn Disease MedDRA version: 20.0;Level: LLT;Classification code 10042759;Term: Symptoms involving ...	Trade Name: METHOTREXATE - 20 MG/0.8 ML SOLUZIONE INIETTABILE 4 SIRINGHE PRERIEMPITE MONOUSO DA 1.25 ...	UMBERTO I - POLICLINICO DI ROMA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	312	Phase 4	France;Czechia;Czech Republic;Hungary;Poland;Belgium;Netherlands;Germany;United Kingdom;Italy

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97. Ulcerative colitis

Clinical trials : 2,630 / Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202

trials per page:

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04818788 (ClinicalTrials.gov)	April 1, 2021	20/3/2021	Hematological Indices and Fecal Calprotectin Predict Histological Remission in Ulcerative Colitis	Hematological Indices and Fecal Calprotectin as Predictors of Histological Remission in Ulcerative C ...	Ulcerative Colitis	Drug: Biological Drug	Assiut University	NULL	Not yet recruiting	18 Years	55 Years	All	24		NULL

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