Levodopa-Carbidopa

( DrugBank: Carbidopa, Levodopa / KEGG DRUG: Carbidopa, Levodopa )

2 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	37

ID	Disease name (Link within this page)	Number of trials
90	Retinitis pigmentosa	1

6. Parkinson disease

Clinical trials : 2,307 / Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000040889	2020/06/24	24/06/2020	Comparison of gastrointestinal function before and after levodopa-carbidopacontinuous infusion gel ( ...	Comparison of gastrointestinal function before and after levodopa-carbidopacontinuous infusion gel ( ...	Parkinson's disease	Levodopa-carbidopa continuous infusion gel (LCIG) therapy	Fujita Health University School of MedicineDepartment of Gastroenterology	NULL	Recruiting	20years-old	Not applicable	Male and Female	200	Phase 4	Japan
2	EUCTR2016-001403-23-HU (EUCTR)	23/01/2018	22/01/2018	12-Week study comparing Levodopa-CarbidopaIntestinal Gel / Levodopa Carbidopa Enteral Suspension to ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Dyskinesia in advanced Parkinson's disease MedDRA version: 20.0;Level: LLT;Classification code 10013 ...	Trade Name: Duodopa INN or Proposed INN: Levodopa Other descriptive name: LEVODOPA INN or Proposed INN: ...	AbbVie Deutschland GmbH & Co. KG	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 3	United States;Hungary;Slovakia;European Union;Greece;Finland;Spain
3	EUCTR2014-004865-26-GR (EUCTR)	01/08/2017	25/04/2017	26-Week Study Comparing Levodopa-CarbidopaIntestinal Gel to Optimized Medical Treatment on Non-Motor ...	An Open-label, Randomized 26-Week Study Comparing Levodopa-CarbidopaINteStInal Gel (LCIG) Therapy to ...	Non-motor symptoms in advanced Parkinson's disease MedDRA version: 20.0;Level: LLT;Classification co ...	Trade Name: Duodopa INN or Proposed INN: Levodopa Other descriptive name: LEVODOPA INN or Proposed INN: ...	AbbVie Deutschland GmbH & Co. KG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	88	Phase 3	United States;European Union;Canada;Greece;Spain;Australia;Germany;Italy;Sweden
4	EUCTR2016-001403-23-GR (EUCTR)	31/03/2017	14/10/2016	12-Week study comparing Levodopa-CarbidopaIntestinal Gel / Levodopa Carbidopa Enteral Suspension to ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Dyskinesia in advanced Parkinson's disease MedDRA version: 19.0;Level: LLT;Classification code 10013 ...	Trade Name: Duodopa INN or Proposed INN: Levodopa Other descriptive name: LEVODOPA INN or Proposed INN: ...	AbbVie Deutschland GmbH & Co. KG	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 3	United States;Hungary;Slovakia;European Union;Greece;Finland;Spain
5	EUCTR2016-001403-23-FI (EUCTR)	22/02/2017	31/08/2016	12-Week study comparing Levodopa-CarbidopaIntestinal Gel / Levodopa Carbidopa Enteral Suspension to ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Dyskinesia in advanced Parkinson's disease MedDRA version: 19.0;Level: LLT;Classification code 10013 ...	Trade Name: Duodopa INN or Proposed INN: Levodopa Other descriptive name: LEVODOPA INN or Proposed INN: ...	AbbVie Deutschland GmbH & Co. KG	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 3	United States;Hungary;Slovakia;European Union;Greece;Finland;Spain
6	NCT02799381 (ClinicalTrials.gov)	February 9, 2017	10/6/2016	A Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbidopa-Levodopa Enteral Suspension ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Parkinson's Disease (PD)	Drug: Optimized antiparkinsonian treatment;Drug: Levodopa-CarbidopaIntestinal Gel (LCIG);Device: CAD ...	AbbVie	NULL	Completed	30 Years	N/A	All	63	Phase 3	United States;Finland;Greece;Hungary;Italy;Slovakia;Spain
7	EUCTR2016-001403-23-SK (EUCTR)	29/11/2016	07/09/2016	12-Week study comparing Levodopa-CarbidopaIntestinal Gel / Levodopa Carbidopa Enteral Suspension to ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Dyskinesia in advanced Parkinson's disease MedDRA version: 20.0;Level: LLT;Classification code 10013 ...	Trade Name: Duodopa INN or Proposed INN: Levodopa Other descriptive name: LEVODOPA INN or Proposed INN: ...	AbbVie Deutschland GmbH & Co. KG	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 3	United States;Hungary;European Union;Slovakia;Greece;Finland;Spain
8	EUCTR2016-001403-23-ES (EUCTR)	14/11/2016	15/11/2016	12-Week study comparing Levodopa-CarbidopaIntestinal Gel / Levodopa Carbidopa Enteral Suspension to ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Dyskinesia in advanced Parkinson's disease MedDRA version: 19.0;Level: LLT;Classification code 10013 ...	Trade Name: Duodopa INN or Proposed INN: Levodopa Other descriptive name: LEVODOPA INN or Proposed INN: ...	AbbVie Deutschland GmbH & Co. KG	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 3	United States;Hungary;Slovakia;European Union;Greece;Finland;Spain
9	EUCTR2016-001403-23-IT (EUCTR)	13/09/2016	06/09/2021	12-Week study comparing Levodopa-CarbidopaIntestinal Gel / Levodopa Carbidopa Enteral Suspension to ...	An Open-label, Randomized 12 Week Study Comparing Efficacy of Levodopa-CarbidopaIntestinal Gel/Carbi ...	Dyskinesia in advanced Parkinson's disease MedDRA version: 21.1;Level: LLT;Classification code 10013 ...	Trade Name: Duodopa Product Name: na Product Code: [na] INN or Proposed INN: LEVODOPA INN or Proposed IN ...	ABBVIE DEUTSCHLAND GMBH & CO. KG	NULL	Not Recruiting			Female: yes Male: yes	60	Phase 3	United States;Hungary;Slovakia;European Union;Greece;Finland;Spain;Italy
10	NCT02549092 (ClinicalTrials.gov)	October 26, 2015	11/9/2015	A Study to Examine the Effect of Levodopa-CarbidopaIntestinal Gel (LCIG) Therapy Relative to That of ...	An Open-label, Randomized 26-Week Study Comparing Levodopa-CarbidopaINteStInal Gel (LCIG) THerapy to ...	Advanced Parkinson's Disease	Drug: Optimized Medical Treatment;Drug: Levodopa-CarbidopaIntestinal Gel;Device: Nasojejunal (NJ) tu ...	AbbVie	NULL	Completed	30 Years	N/A	All	89	Phase 3	United States;Australia;Canada;Germany;Greece;Italy;Korea, Republic of;Spain;Sweden

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90. Retinitis pigmentosa

Clinical trials : 147 / Drugs : 176 - (DrugBank : 43) / Drug target genes : 49 - Drug target pathways : 110

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02837640 (ClinicalTrials.gov)	June 2016	22/6/2016	Studying a Potential Protective Effect of L-Dopa on Retinitis Pigmentosa	The Effect of L-Dopa on the Progression of Retinitis Pigmentosa	Retinitis Pigmentosa	Drug: levodopa-carbidopa	Beirut Eye Specialist Hospital	NULL	Recruiting	10 Years	65 Years	Both	50	Phase 2	Lebanon

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