Cy

( DrugBank: - / KEGG DRUG: - )

1 disease

ID	Disease name (Link within this page)	Number of trials
60	Aplastic anemia	120

60. Aplastic anemia

Clinical trials : 245 / Drugs : 318 - (DrugBank : 86) / Drug target genes : 44 - Drug target pathways : 166

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Showing 1 to 10 of 120 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05323617 (ClinicalTrials.gov)	May 15, 2023	5/4/2022	Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Imm ...	Two Arm Bridging Study to Evaluate the Efficacy of Romiplostim in the Treatment of Adult Severe Apla ...	Severe Aplastic Anemia (SAA)	Drug: Romiplostim;Drug: Antithymocyte Globulin;Drug: Cyclosporine A	Amgen	NULL	Not yet recruiting	18 Years	N/A	All	40	Phase 2	NULL
2	NCT05600426 (ClinicalTrials.gov)	January 25, 2023	20/10/2022	A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Ap ...	A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation With Immune Suppr ...	Severe Aplastic Anemia	Drug: cyclosporine;Procedure: Matched Unrelated Donor Hematopoetic Stem Cell Transplant;Drug: horse ...	Boston Children's Hospital	Center for International Blood and Marrow Transplant Research;National Institutes of Health (NIH);Na ...	Recruiting	0 Years	25 Years	All	234	Phase 3	United States
3	ChiCTR2200056659	2023-01-16	2022-02-10	Allopurinol in the treatment of cyclosporine-induced hyperuricemia in children with aplastic anemia: ...	Allopurinol in the treatment of cyclosporine-induced hyperuricemia in children with aplastic anemia: ...	hyperuricemia	Allopurinol group:Receive allopurinol tablets;Placebo group:Receive placebo;	The Seventh Affiliated Hospital, Sun Yat-sen University	NULL	Pending	1	18	Both	Allopurinol group:20;Placebo group:20;	Phase 4	China
4	NCT05660785 (ClinicalTrials.gov)	December 1, 2022	23/11/2022	Herombopag Added to Cyclosporine in Non Severe Aplastic Anemia	The Efficacy and Safety of Herombopag Combined With Cyclosporine for Patients With Non Severe Aplast ...	Non Severe Aplastic Anemia;Untreated	Drug: Herombopag	Institute of Hematology & Blood Diseases Hospital	Jiangsu Hengrui Pharmaceuticals Co.,Ltd	Recruiting	18 Years	N/A	All	54	Phase 2	China
5	NCT05031897 (ClinicalTrials.gov)	October 25, 2021	31/8/2021	Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Und ...	A 2 Step Approach to Haploidentical Transplant Using Radiation-Based Reduced Intensity Conditioning	Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Aplastic Anemia;Chronic Lymphocytic Leukemia;Chr ...	Procedure: Hematopoietic Cell Transplantation;Drug: Mycophenolate Mofetil;Drug: Tacrolimus;Drug: Cyc ...	Thomas Jefferson University	NULL	Recruiting	18 Years	N/A	All	67	Phase 2	United States
6	NCT05049668 (ClinicalTrials.gov)	October 2021	13/9/2021	RACE 2: a Long Term Follow-up of Patients Participating in the RACE Trial	Long-term Follow-up of Patients Participating in RACE: the Prospective Randomized Multicenter Study ...	Severe Aplastic Anemia	Drug: ATGAM plus CsA with or without Eltrombopag	European Society for Blood and Marrow Transplantation	NULL	Enrolling by invitation	N/A	N/A	All	197		France
7	ChiCTR2100050948	2021-09-10	2021-09-08	Comparison of clinical efficacy and safety of hematopoietic stem cell transplantation and immunosupp ...	Comparison of clinical efficacy and safety of hematopoietic stem cell transplantation and immunosupp ...	Hepatitis-associated Aplastic Anemia	ematopoietic stem cell transplantation group:Nil;ATG combined with cyclosporine group :Nil;	Zhejiang Provincial Hospital of Traditional Chinese Medicine	NULL	Recruiting	1	50	Both	ematopoietic stem cell transplantation group:30;ATG combined with cyclosporine group :30;		China
8	ChiCTR2100047288	2021-06-01	2021-06-11	Efficacy and safety of combined immunosuppressive therapy plus umbilical cord blood infusion in myel ...	Efficacy and safety of combined immunosuppressive therapy plus umbilical cord blood infusion in myel ...	myelodysplastic syndromes/aplastic anemi	Experimental group1:According to the classification, ATG + CsA/CSA alone is used as the pretreatment ...	The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)	NULL	Recruiting	18	90	Both	Experimental group1:10;Experimental group2:10;		China
9	ChiCTR2100043229	2021-02-22	2021-02-09	A Single-Center, Single-Arm, Phase II Clinical Study of the Efficacy and Safety of Cyclosporine Comb ...	A Single-Center, Single-Arm, Phase II Clinical Study of the Efficacy and Safety of Cyclosporine Comb ...	Aplastic anemia	Durgs Group:Elrombopag combined with Cyclosporine;	Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences	NULL	Recruiting	18	85	Both	Durgs Group:61;	Phase 2	China
10	ChiCTR2000041485	2021-01-01	2020-12-27	Efficacy of Danazol after no response to cyclosporin in transfusion independent aplastic anemia: a p ...	Efficacy of Danazol after no response to cyclosporin in transfusion independent aplastic anemia: a p ...	transfusion independent aplastic anemia	experimental group:Cyclosporine combined with danazol;control group:Cyclosporine;	Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking U ...	NULL	Recruiting			Both	experimental group:152;control group:76;	Phase 4	China

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