PLN-74809

( DrugBank: PLN-74809 / KEGG DRUG: - )

2 diseases

ID	Disease name (Link within this page)	Number of trials
85	Idiopathic interstitial pneumonia	6

ID	Disease name (Link within this page)	Number of trials
94	Primary sclerosing cholangitis	5

85. Idiopathic interstitial pneumonia

Clinical trials : 627 / Drugs : 443 - (DrugBank : 120) / Drug target genes : 99 - Drug target pathways : 212

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05621252 (ClinicalTrials.gov)	July 13, 2022	2/11/2022	Imaging Evaluation of PLN-74809 in Participants With IPF (PLN-74809)	A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Evaluation of PLN-74809on Type 1 Collagen ...	Idiopathic Pulmonary Fibrosis	Drug: PLN-74809;Drug: Placebo	Pliant Therapeutics, Inc.	NULL	Recruiting	40 Years	N/A	All	12	Phase 2	United States
2	EUCTR2019-002709-23-NL (EUCTR)	16/02/2021	06/08/2020	A study to assess the efficacy, safety and pharmacokinetics of PLN-74809in participants with idiopat ...	A randomized, double-blind, dose-ranging, placebo-controlled Phase 2a evaluation of the safety, tole ...	Idiopathic pulmonary fibrosis (IPF) MedDRA version: 21.1;Level: PT;Classification code 10021240;Term ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not Available Other descriptive na ...	Pliant Therapeutics Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	112	Phase 2	France;United States;Canada;Belgium;Australia;Germany;Netherlands;United Kingdom;New Zealand;Italy;K ...
3	EUCTR2019-002709-23-IT (EUCTR)	29/12/2020	24/05/2021	A study to assess the efficacy, safety and pharmacokinetics of PLN-74809in participants with idiopat ...	A randomized, double-blind, dose-ranging, placebo-controlled Phase 2a evaluation of the safety, tole ...	idiopathic pulmonary fibrosis MedDRA version: 20.0;Level: SOC;Classification code 10038738;Term: Res ...	Product Name: PLN-74809 Product Code: [PLN-74809] Other descriptive name: PLN-74809-000	Pliant Therapeutics Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	84	Phase 2	France;United States;Canada;Belgium;Australia;Netherlands;Germany;United Kingdom;New Zealand;Italy
4	EUCTR2019-002709-23-DE (EUCTR)	18/12/2020	31/01/2020	A study to assess the efficacy, safety and pharmacokinetics of PLN-74809in participants with idiopat ...	A randomized, double-blind, dose-ranging, placebo-controlled Phase 2a evaluation of the safety, tole ...	Idiopathic pulmonary fibrosis (IPF) MedDRA version: 21.1;Level: PT;Classification code 10021240;Term ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not Available Other descriptive na ...	Pliant Therapeutics Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	112	Phase 2	United States;France;Canada;Belgium;Australia;Netherlands;Germany;United Kingdom;New Zealand;Italy;K ...
5	EUCTR2019-002709-23-GB (EUCTR)	06/11/2020	24/01/2020	A study to assess the efficacy, safety and pharmacokinetics of PLN-74809in participants with idiopat ...	A randomized, double-blind, dose-ranging, placebo-controlled Phase 2a evaluation of the safety, tole ...	Idiopathic pulmonary fibrosis (IPF) MedDRA version: 21.1;Level: PT;Classification code 10021240;Term ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not Available Other descriptive na ...	Pliant Therapeutics Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	40	Phase 2	United States;France;Canada;Belgium;Australia;Netherlands;Germany;New Zealand;Italy;United Kingdom
6	NCT04072315 (ClinicalTrials.gov)	September 9, 2019	23/8/2019	Phase 2a Evaluation of PLN-74809on avß6 Receptor Occupancy Using PET Imaging in Participants With IP ...	A Phase 2a Evaluation of PLN-74809on avß6 Receptor Occupancy Using PET Imaging in Participants With ...	Idiopathic Pulmonary Fibrosis	Drug: PLN-74809;Radiation: Knottin tracer	Pliant Therapeutics, Inc.	Stanford University	Completed	40 Years	N/A	All	12	Phase 2	United States

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94. Primary sclerosing cholangitis

Clinical trials : 148 / Drugs : 118 - (DrugBank : 39) / Drug target genes : 18 - Drug target pathways : 141

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Showing 1 to 5 of 5 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-001428-33-NL (EUCTR)	27/07/2021	31/08/2020	A study to assess efficacy, safety and pharmacokinetics of PLN-74809in participants with primary scl ...	A randomized, double-blind, dose-ranging, placebo-controlled, Phase 2a evaluation of the safety, tol ...	Primary sclerosing cholangitis (PSC) MedDRA version: 20.1;Level: LLT;Classification code 10036732;Te ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not yet established Product Name: ...	Pliant Therapeutics, Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	112	Phase 2	France;United States;Canada;Belgium;Austria;Australia;Germany;Netherlands;United Kingdom
2	EUCTR2020-001428-33-DE (EUCTR)	15/02/2021	17/07/2020	A study to assess efficacy, safety and pharmacokinetics of PLN-74809in participants with primary scl ...	A randomized, double-blind, dose-ranging, placebo-controlled, Phase 2a evaluation of the safety, tol ...	Primary sclerosing cholangitis (PSC) MedDRA version: 20.1;Level: LLT;Classification code 10036732;Te ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not yet established Product Name: ...	Pliant Therapeutics, Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	112	Phase 2	France;United States;Canada;Belgium;Austria;Australia;Netherlands;Germany;United Kingdom
3	EUCTR2020-001428-33-BE (EUCTR)	10/11/2020	23/07/2020	A study to assess efficacy, safety and pharmacokinetics of PLN-74809in participants with primary scl ...	A randomized, double-blind, dose-ranging, placebo-controlled, Phase 2a evaluation of the safety, tol ...	Primary sclerosing cholangitis (PSC) MedDRA version: 20.1;Level: LLT;Classification code 10036732;Te ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: bexotegrast Product Name: PLN-7480 ...	Pliant Therapeutics, Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	112	Phase 2	France;United States;Canada;Belgium;Austria;Australia;Norway;Germany;Netherlands;United Kingdom
4	EUCTR2020-001428-33-GB (EUCTR)	05/11/2020	22/06/2020	A study to assess efficacy, safety and pharmacokinetics of PLN-74809in participants with primary scl ...	A randomized, double-blind, dose-ranging, placebo-controlled, Phase 2a evaluation of the safety, tol ...	Primary sclerosing cholangitis (PSC) MedDRA version: 20.1;Level: LLT;Classification code 10036732;Te ...	Product Name: PLN-74809 Product Code: PLN-74809 INN or Proposed INN: Not yet established	Pliant Therapeutics, Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	84	Phase 2	United States;France;Canada;Belgium;Austria;Australia;Norway;Netherlands;Germany;United Kingdom
5	NCT04480840 (ClinicalTrials.gov)	July 27, 2020	13/7/2020	Phase 2a Evaluation of Safety, Tolerability, and Pharmacokinetics of PLN-74809in Patients With Prima ...	A Randomized, Double-blind, Dose-ranging, Placebo-controlled, Phase 2a Evaluation of the Safety, Tol ...	Primary Sclerosing Cholangitis	Drug: PLN-74809;Drug: Placebo	Pliant Therapeutics, Inc.	NULL	Recruiting	18 Years	75 Years	All	112	Phase 2	United States;Australia;Austria;Belgium;Canada;France;Germany;Netherlands;United Kingdom

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